0XYGEN

75/100 · Elevated

Manufactured by Air Source Industries Inc

High Serious Reaction Rate for Oxygen Therapy

129,410 FDA adverse event reports analyzed

Last updated: 2026-05-12

About 0XYGEN

0XYGEN is a medication tracked in the FDA Adverse Event Reporting System (FAERS), manufactured by Air Source Industries Inc. Based on analysis of 129,410 FDA adverse event reports, 0XYGEN has a safety score of 75 out of 100. This score indicates a relatively favorable safety profile, with fewer or less severe adverse events compared to many other tracked medications. The most commonly reported adverse reactions for 0XYGEN include DYSPNOEA, COUGH, HEADACHE, DIARRHOEA, FATIGUE. This page provides a comprehensive breakdown of reported side effects, safety signals, patient demographics, and AI-powered safety analysis for 0XYGEN.

AI Safety Analysis

0xygen has a safety concern score of 75 out of 100, placing it in the elevated concern category based on analysis of FDA adverse event data. The FDA has received approximately 129,410 adverse event reports for this medication, which is primarily manufactured by Air Source Industries Inc.

The most commonly reported adverse events include Dyspnoea, Cough, Headache. Of classified reports, 68.7% were designated as serious by the FDA, meaning they involved hospitalization, disability, or other significant medical outcomes. The majority of reactions are non-serious, but the serious reaction rate is high at 68.7%.

Reactions such as dyspnea, pneumonia, and respiratory failure are common and can be life-threatening. The reaction diversity is high, indicating a wide range of potential adverse effects. Report volume is substantial, with over 129,000 reports, providing a comprehensive dataset.

Patients taking 0xygen should monitor for the commonly reported side effects and contact their healthcare provider if they experience any unusual symptoms. Oxygen therapy can interact with other medications and may exacerbate underlying conditions such as chronic obstructive pulmonary disease (COPD) and heart failure. Warnings should be followed closely. This analysis is based on voluntary FDA adverse event reports and should not replace professional medical advice.

Safety Score: 75/100

0xygen received a safety concern score of 75/100 (elevated concern). This is based on a 68.7% serious event ratio across 44,827 classified reports. The score accounts for 129,410 total adverse event reports and 100 distinct reaction types. This elevated score indicates a notable proportion of serious adverse events and warrants careful monitoring.

Top Adverse Reactions

DYSPNOEA8,985 reports
COUGH4,252 reports
HEADACHE4,192 reports
DIARRHOEA3,786 reports
FATIGUE3,727 reports
PNEUMONIA3,654 reports
NAUSEA3,564 reports
DIZZINESS3,036 reports
OXYGEN SATURATION DECREASED2,759 reports
DEATH2,424 reports
MALAISE2,182 reports
ASTHENIA2,164 reports
OFF LABEL USE2,128 reports
HYPOTENSION2,106 reports
VOMITING1,929 reports
WEIGHT DECREASED1,897 reports
PAIN1,889 reports
FALL1,844 reports
DRUG INEFFECTIVE1,823 reports
CHEST PAIN1,569 reports
CHRONIC OBSTRUCTIVE PULMONARY DISEASE1,565 reports
DYSPNOEA EXERTIONAL1,548 reports
DECREASED APPETITE1,501 reports
CONDITION AGGRAVATED1,478 reports
PAIN IN EXTREMITY1,416 reports
OEDEMA PERIPHERAL1,409 reports
PYREXIA1,344 reports
FLUID RETENTION1,266 reports
ARTHRALGIA1,264 reports
FEELING ABNORMAL1,248 reports
RESPIRATORY FAILURE1,234 reports
HYPOXIA1,187 reports
PERIPHERAL SWELLING1,172 reports
PRODUCTIVE COUGH1,170 reports
BACK PAIN1,147 reports
EPISTAXIS1,137 reports
NASOPHARYNGITIS1,131 reports
WEIGHT INCREASED1,117 reports
ANAEMIA1,097 reports
PRODUCT DOSE OMISSION ISSUE1,094 reports
CHEST DISCOMFORT1,037 reports
PULMONARY HYPERTENSION1,001 reports
ANXIETY979 reports
URINARY TRACT INFECTION918 reports
PULMONARY ARTERIAL HYPERTENSION910 reports
NASAL CONGESTION909 reports
CONSTIPATION894 reports
INFUSION SITE PAIN894 reports
COVID 19884 reports
HEART RATE INCREASED878 reports
INSOMNIA876 reports
THERAPY NON RESPONDER875 reports
ABDOMINAL DISCOMFORT861 reports
SYNCOPE855 reports
CARDIAC FAILURE CONGESTIVE841 reports
ABDOMINAL PAIN UPPER827 reports
LUNG DISORDER822 reports
RASH815 reports
CARDIAC FAILURE814 reports
HYPERTENSION795 reports
ATRIAL FIBRILLATION793 reports
OEDEMA788 reports
PALPITATIONS787 reports
BLOOD PRESSURE DECREASED767 reports
BRONCHITIS764 reports
OROPHARYNGEAL PAIN752 reports
PRURITUS738 reports
SEASONAL ALLERGY737 reports
LOSS OF CONSCIOUSNESS736 reports
FLUSHING728 reports
GAIT DISTURBANCE710 reports
SEPSIS699 reports
ILLNESS697 reports
DEHYDRATION696 reports
THROAT IRRITATION693 reports
PULMONARY OEDEMA691 reports
PAIN IN JAW690 reports
INFLUENZA677 reports
SINUSITIS671 reports
PRODUCT USE ISSUE657 reports
PLEURAL EFFUSION654 reports
SOMNOLENCE648 reports
ABDOMINAL PAIN636 reports
TREMOR626 reports
ABDOMINAL DISTENSION622 reports
MYALGIA620 reports
WHEEZING603 reports
INFECTION595 reports
MUSCLE SPASMS595 reports
ASTHMA586 reports
CARDIAC ARREST580 reports
INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION578 reports
INFUSION SITE ERYTHEMA572 reports
RHINORRHOEA571 reports
CARDIAC DISORDER570 reports
HAEMOGLOBIN DECREASED563 reports
BLOOD PRESSURE INCREASED562 reports
GENERAL PHYSICAL HEALTH DETERIORATION552 reports
ERYTHEMA544 reports
ACUTE RESPIRATORY FAILURE542 reports

Key Safety Signals

  • High rate of serious reactions (30,811 out of 44,827, 68.7%)
  • Common reactions include dyspnea, pneumonia, and respiratory failure
  • A wide range of reactions reported, indicating potential for various adverse effects

Patient Demographics

Adverse event reports by sex: Female: 27,492, Male: 14,888, Unknown: 52. The most frequently reported age groups are age 71 (877 reports), age 74 (836 reports), age 75 (821 reports). These demographics reflect reporting patterns and may not represent the full patient population.

Report Outcomes

Out of 44,827 classified reports for 0XYGEN:

  • Serious: 30,811 reports (68.7%) — includes hospitalization, disability, life-threatening events, or death
  • Non-Serious: 14,016 reports (31.3%)
Serious 68.7%Non-Serious 31.3%

The FDA classifies an adverse event as “serious” if it results in death, hospitalization, disability, congenital anomaly, or requires intervention to prevent permanent damage.

Demographics Breakdown

Reports by Sex

Female27,492 (64.8%)
Male14,888 (35.1%)
Unknown52 (0.1%)

Reports by Age

Age 71877 reports
Age 74836 reports
Age 75821 reports
Age 69818 reports
Age 73813 reports
Age 72780 reports
Age 70761 reports
Age 76753 reports
Age 68748 reports
Age 67737 reports
Age 77728 reports
Age 66707 reports
Age 65676 reports
Age 79651 reports
Age 62648 reports
Age 78647 reports
Age 64640 reports
Age 63622 reports
Age 61602 reports
Age 80568 reports

Demographics reflect voluntary FDA adverse event reporting patterns and may not represent the full patient population.

Drug Interactions & Warnings

Oxygen therapy can interact with other medications and may exacerbate underlying conditions such as chronic obstructive pulmonary disease (COPD) and heart failure. Warnings should be followed closely.

What You Should Know

If you are taking 0xygen, here are important things to know. The most commonly reported side effects include dyspnoea, cough, headache, diarrhoea, fatigue. While many of these may be mild and temporary, you should contact your healthcare provider if any symptoms are severe or persistent. Patients should closely follow prescribed oxygen therapy schedules and report any unusual symptoms to their healthcare provider. Ensure that oxygen equipment is properly maintained and used as directed to prevent complications. If you experience a serious adverse reaction, seek emergency medical attention immediately or call 911. You can report side effects to the FDA's MedWatch program at 1-800-FDA-1088.

Regulatory Context

The FDA continues to monitor oxygen therapy for safety. Healthcare providers should report any adverse events to the FDA's MedWatch program.

Frequently Asked Questions

How many adverse event reports has the FDA received for 0xygen?

The FDA has received approximately 129,410 adverse event reports associated with 0xygen. These reports come from healthcare professionals, consumers, and manufacturers through the FDA Adverse Event Reporting System (FAERS). Note that the number of reports does not directly indicate the frequency of side effects, as adverse events are voluntarily reported and may be underrepresented.

What are the most commonly reported side effects of 0xygen?

The most frequently reported adverse events for 0xygen include Dyspnoea, Cough, Headache, Diarrhoea, Fatigue. By volume, the top reported reactions are: Dyspnoea (8,985 reports), Cough (4,252 reports), Headache (4,192 reports). These figures reflect FDA adverse event reports and may not represent the true incidence rate of these side effects in all patients taking 0xygen.

What percentage of 0xygen adverse event reports are serious?

Out of 44,827 classified reports, 30,811 (68.7%) were classified as serious and 14,016 as non-serious. The FDA classifies an event as "serious" if it results in death, hospitalization, disability, or other medically significant outcomes. A higher serious-event ratio warrants closer attention but does not necessarily mean the drug is unsafe.

Who reports adverse events for 0xygen (by sex)?

Adverse event reports for 0xygen break down by patient sex as follows: Female: 27,492, Male: 14,888, Unknown: 52. This distribution reflects reporting patterns rather than actual risk differences between groups. Reporting rates can be influenced by prescribing patterns, disease demographics, and reporting behavior.

What age groups report the most side effects for 0xygen?

The most frequently reported age groups for 0xygen adverse events are: age 71: 877 reports, age 74: 836 reports, age 75: 821 reports, age 69: 818 reports, age 73: 813 reports. Age-related reporting patterns can reflect both the demographics of the patient population and potential age-related susceptibility to certain side effects.

Who manufactures 0xygen?

The primary manufacturer associated with 0xygen adverse event reports is Air Source Industries Inc. Multiple manufacturers may produce generic versions of this drug. The manufacturer listed reflects the most frequently reported brand in FDA adverse event data.

What other side effects have been reported for 0xygen?

Beyond the most common reactions, other reported adverse events for 0xygen include: Pneumonia, Nausea, Dizziness, Oxygen Saturation Decreased, Death. Less common side effects can still be clinically significant. Patients should report any unusual symptoms to their healthcare provider.

How do I report a side effect from 0xygen?

You can report adverse events from 0xygen to the FDA through their MedWatch program at www.fda.gov/medwatch, by calling 1-800-FDA-1088, or by completing Form FDA 3500. Healthcare professionals, consumers, and manufacturers can all submit reports. Reporting helps the FDA monitor drug safety after approval.

What is 0xygen's safety score and what does it mean?

0xygen has a safety concern score of 75 out of 100 (elevated concern). This score is calculated from the ratio of serious to non-serious adverse events, the diversity of reported reactions, and the overall volume of reports relative to usage. The majority of reactions are non-serious, but the serious reaction rate is high at 68.7%.

What are the key safety signals for 0xygen?

Key safety signals identified in 0xygen's adverse event data include: High rate of serious reactions (30,811 out of 44,827, 68.7%). Common reactions include dyspnea, pneumonia, and respiratory failure. A wide range of reactions reported, indicating potential for various adverse effects. These signals are derived from patterns in FDA reports and should be discussed with a healthcare provider for personalized assessment.

Does 0xygen interact with other drugs?

Oxygen therapy can interact with other medications and may exacerbate underlying conditions such as chronic obstructive pulmonary disease (COPD) and heart failure. Warnings should be followed closely. Always inform your healthcare provider about all medications, supplements, and over-the-counter drugs you are taking before starting 0xygen.

What should patients know before taking 0xygen?

Patients should closely follow prescribed oxygen therapy schedules and report any unusual symptoms to their healthcare provider. Ensure that oxygen equipment is properly maintained and used as directed to prevent complications.

Are 0xygen side effects well-documented?

0xygen has 129,410 adverse event reports on file with the FDA. Reactions such as dyspnea, pneumonia, and respiratory failure are common and can be life-threatening. The volume of reports for 0xygen reflects both the drug's usage level and the vigilance of the reporting community.

What is the FDA's position on 0xygen?

The FDA continues to monitor oxygen therapy for safety. Healthcare providers should report any adverse events to the FDA's MedWatch program. For the most current regulatory information, check the FDA's drug labeling database or consult your pharmacist.

Related Drugs

Drugs related to 0XYGEN based on therapeutic use, drug class, or shared indications:

OXYGENCOPDHeart Failure
Important Disclaimer: This content is generated by AI analysis of FDA adverse event reports and is provided for informational purposes only. It is not medical advice. Adverse event reports submitted to the FDA do not prove that a medication caused the reported side effect. Always consult your healthcare provider before starting, stopping, or changing any medication. If you experience a serious side effect, contact your doctor or call 911 immediately.