ARTICAINE HYDROCHLORIDE AND EPINEPHRINE

N/A

Manufactured by Benco Dental

433 FDA adverse event reports analyzed

Last updated: 2026-04-15

About ARTICAINE HYDROCHLORIDE AND EPINEPHRINE

ARTICAINE HYDROCHLORIDE AND EPINEPHRINE is a medication tracked in the FDA Adverse Event Reporting System (FAERS), manufactured by Benco Dental. The most commonly reported adverse reactions for ARTICAINE HYDROCHLORIDE AND EPINEPHRINE include ELECTROCARDIOGRAM ST SEGMENT ELEVATION, HYPOXIA, OVERDOSE, DRUG INEFFECTIVE, HYPOAESTHESIA. This page provides a comprehensive breakdown of reported side effects, safety signals, patient demographics, and AI-powered safety analysis for ARTICAINE HYDROCHLORIDE AND EPINEPHRINE.

Top Adverse Reactions

ELECTROCARDIOGRAM ST SEGMENT ELEVATION17 reports
HYPOXIA15 reports
OVERDOSE14 reports
DRUG INEFFECTIVE13 reports
HYPOAESTHESIA11 reports
HYPOAESTHESIA ORAL11 reports
CARDIAC ARREST10 reports
NAUSEA10 reports
TOXICITY TO VARIOUS AGENTS10 reports
ARRHYTHMIA9 reports
DYSPNOEA7 reports
HYPORESPONSIVE TO STIMULI7 reports
LOCAL ANAESTHETIC SYSTEMIC TOXICITY7 reports
NERVE INJURY7 reports
ANAESTHETIC COMPLICATION6 reports
CRANIOCEREBRAL INJURY6 reports
FALL6 reports
HYPERSOMNIA6 reports
LOSS OF CONSCIOUSNESS6 reports
MYOTONIC DYSTROPHY6 reports
OXYGEN SATURATION DECREASED6 reports
PAIN6 reports
PNEUMONIA6 reports
PNEUMONITIS ASPIRATION6 reports
ANAPHYLACTIC REACTION5 reports
CONDITION AGGRAVATED5 reports
DRUG CLEARANCE DECREASED5 reports
KOUNIS SYNDROME5 reports
MALAISE5 reports
PARAESTHESIA5 reports
PNEUMOTHORAX5 reports
SEIZURE5 reports
VOMITING5 reports
ANAPHYLACTIC SHOCK4 reports
CHILLS4 reports
DIZZINESS4 reports
DRUG INTERACTION4 reports
FATIGUE4 reports
GLOSSODYNIA4 reports
HEART RATE INCREASED4 reports
PALPITATIONS4 reports
PARAESTHESIA ORAL4 reports
PERIPHERAL ISCHAEMIA4 reports
RESPIRATORY ARREST4 reports
TYPE IV HYPERSENSITIVITY REACTION4 reports
URTICARIA4 reports
ANGIOEDEMA3 reports
ANXIETY3 reports
ATRIAL FIBRILLATION3 reports
CROSS SENSITIVITY REACTION3 reports
HYPERSENSITIVITY3 reports
HYPOTENSION3 reports
INJECTION SITE SWELLING3 reports
MUSCULAR WEAKNESS3 reports
MUSCULOSKELETAL STIFFNESS3 reports
MYOCARDIAL INFARCTION3 reports
OFF LABEL USE3 reports
PALLOR3 reports
POST PROCEDURAL COMPLICATION3 reports
PRESYNCOPE3 reports
PRURITUS3 reports
RASH3 reports
SENSORY LOSS3 reports
SWELLING FACE3 reports
SYNCOPE3 reports
XIITH NERVE INJURY3 reports
AGEUSIA2 reports
AGITATION2 reports
ATAXIA2 reports
BACK PAIN2 reports
BRADYCARDIA2 reports
CARDIOGENIC SHOCK2 reports
CHEST PAIN2 reports
DRUG HYPERSENSITIVITY2 reports
DRY MOUTH2 reports
DYSPHAGIA2 reports
DYSTONIA2 reports
EPILEPSY2 reports
FACE OEDEMA2 reports
FACIAL PARALYSIS2 reports
GAZE PALSY2 reports
GENERAL PHYSICAL HEALTH DETERIORATION2 reports
HYPERTENSION2 reports
LIP DISORDER2 reports
LIP PAIN2 reports
LOCAL SWELLING2 reports
MYDRIASIS2 reports
NECK PAIN2 reports
NEUROLOGIC NEGLECT SYNDROME2 reports
PAIN IN JAW2 reports
PULSELESS ELECTRICAL ACTIVITY2 reports
RESPIRATION ABNORMAL2 reports
RESPIRATORY FAILURE2 reports
RHINORRHOEA2 reports
SALIVARY HYPERSECRETION2 reports
SKIN TEST POSITIVE2 reports
STRIDOR2 reports
TACHYCARDIA2 reports
TORSADE DE POINTES2 reports
TREMOR2 reports

Report Outcomes

Out of 137 classified reports for ARTICAINE HYDROCHLORIDE AND EPINEPHRINE:

Serious 78.1%Non-Serious 21.9%

The FDA classifies an adverse event as “serious” if it results in death, hospitalization, disability, congenital anomaly, or requires intervention to prevent permanent damage.

Demographics Breakdown

Reports by Sex

Female68 (57.6%)
Male50 (42.4%)

Reports by Age

Age 3720 reports
Age 725 reports
Age 44 reports
Age 314 reports
Age 404 reports
Age 644 reports
Age 413 reports
Age 533 reports
Age 553 reports
Age 633 reports
Age 693 reports
Age 172 reports
Age 322 reports
Age 352 reports
Age 362 reports
Age 452 reports
Age 482 reports
Age 492 reports
Age 512 reports
Age 592 reports

Demographics reflect voluntary FDA adverse event reporting patterns and may not represent the full patient population.

Frequently Asked Questions

How many FDA adverse event reports are associated with ARTICAINE HYDROCHLORIDE AND EPINEPHRINE?

This profile reflects 433 FDA FAERS reports that mention ARTICAINE HYDROCHLORIDE AND EPINEPHRINE. Reporting is voluntary and does not prove that the drug caused any listed event.

Which adverse reactions are most often listed for ARTICAINE HYDROCHLORIDE AND EPINEPHRINE?

Frequently reported terms in FAERS include ELECTROCARDIOGRAM ST SEGMENT ELEVATION, HYPOXIA, OVERDOSE, DRUG INEFFECTIVE, HYPOAESTHESIA, HYPOAESTHESIA ORAL. Rankings reflect reporting volume in this dataset, not confirmed side effect rates in the general population.

Who manufactures ARTICAINE HYDROCHLORIDE AND EPINEPHRINE?

Labeling and FAERS entries often list Benco Dental in connection with ARTICAINE HYDROCHLORIDE AND EPINEPHRINE. Always verify the specific product and NDC with your pharmacist.

Important Disclaimer: This content is generated by AI analysis of FDA adverse event reports and is provided for informational purposes only. It is not medical advice. Adverse event reports submitted to the FDA do not prove that a medication caused the reported side effect. Always consult your healthcare provider before starting, stopping, or changing any medication. If you experience a serious side effect, contact your doctor or call 911 immediately.