ASCORBIC ACID

N/A

Manufactured by McGuff Pharmaceuticals, Inc.

77,147 FDA adverse event reports analyzed

Last updated: 2026-04-14

About ASCORBIC ACID

ASCORBIC ACID is a medication tracked in the FDA Adverse Event Reporting System (FAERS), manufactured by McGuff Pharmaceuticals, Inc.. The most commonly reported adverse reactions for ASCORBIC ACID include FATIGUE, PAIN, NAUSEA, DIARRHOEA, HEADACHE. This page provides a comprehensive breakdown of reported side effects, safety signals, patient demographics, and AI-powered safety analysis for ASCORBIC ACID.

Top Adverse Reactions

FATIGUE2,276 reports
PAIN2,059 reports
NAUSEA1,942 reports
DIARRHOEA1,784 reports
HEADACHE1,762 reports
DRUG INEFFECTIVE1,731 reports
DYSPNOEA1,639 reports
VOMITING1,521 reports
OFF LABEL USE1,469 reports
ASTHENIA1,447 reports
RASH1,360 reports
DIZZINESS1,314 reports
ARTHRALGIA1,257 reports
PRURITUS1,133 reports
PYREXIA1,122 reports
HYPERTENSION1,021 reports
INSOMNIA1,004 reports
PAIN IN EXTREMITY990 reports
FALL969 reports
PNEUMONIA968 reports
JOINT SWELLING965 reports
ABDOMINAL PAIN UPPER961 reports
CONDITION AGGRAVATED919 reports
BACK PAIN900 reports
MALAISE871 reports
ANXIETY853 reports
CHEST PAIN834 reports
CONSTIPATION834 reports
HYPERSENSITIVITY815 reports
ABDOMINAL PAIN813 reports
URTICARIA805 reports
WEIGHT INCREASED796 reports
DRUG HYPERSENSITIVITY789 reports
RHEUMATOID ARTHRITIS781 reports
WEIGHT DECREASED766 reports
CONFUSIONAL STATE761 reports
SINUSITIS761 reports
DEPRESSION748 reports
ABDOMINAL DISCOMFORT733 reports
OEDEMA PERIPHERAL730 reports
PERIPHERAL SWELLING729 reports
ANAEMIA711 reports
DECREASED APPETITE702 reports
ALOPECIA699 reports
MUSCLE SPASMS660 reports
NASOPHARYNGITIS649 reports
LOWER RESPIRATORY TRACT INFECTION638 reports
INFECTION631 reports
ASTHMA628 reports
ARTHROPATHY625 reports
SOMNOLENCE616 reports
GENERAL PHYSICAL HEALTH DETERIORATION615 reports
SWELLING610 reports
HEPATIC ENZYME INCREASED605 reports
COUGH602 reports
GASTROOESOPHAGEAL REFLUX DISEASE601 reports
HYPOAESTHESIA593 reports
CONTUSION582 reports
OSTEOARTHRITIS580 reports
URINARY TRACT INFECTION579 reports
INJURY574 reports
INFUSION RELATED REACTION570 reports
GAIT DISTURBANCE565 reports
DRUG INTOLERANCE558 reports
DEATH557 reports
DRY MOUTH552 reports
IMPAIRED HEALING546 reports
GASTROINTESTINAL DISORDER545 reports
MUSCULOSKELETAL STIFFNESS543 reports
BLOOD CHOLESTEROL INCREASED539 reports
DYSPEPSIA538 reports
PARAESTHESIA531 reports
HYPOTENSION523 reports
CONTRAINDICATED PRODUCT ADMINISTERED521 reports
NIGHT SWEATS493 reports
STOMATITIS488 reports
FLUSHING480 reports
BLISTER477 reports
MOBILITY DECREASED477 reports
FIBROMYALGIA476 reports
ERYTHEMA474 reports
SYSTEMIC LUPUS ERYTHEMATOSUS466 reports
SLEEP DISORDER456 reports
IRRITABLE BOWEL SYNDROME451 reports
PRODUCT USE IN UNAPPROVED INDICATION451 reports
GLOSSODYNIA449 reports
FOLLICULITIS444 reports
WOUND444 reports
PSORIATIC ARTHROPATHY436 reports
PRODUCT USE ISSUE435 reports
DUODENAL ULCER PERFORATION434 reports
SYNOVITIS434 reports
FEELING ABNORMAL429 reports
ABDOMINAL DISTENSION428 reports
TREATMENT FAILURE428 reports
MUSCULAR WEAKNESS420 reports
WHEEZING417 reports
PEMPHIGUS414 reports
PULMONARY EMBOLISM414 reports
SEPSIS412 reports

Report Outcomes

Out of 22,553 classified reports for ASCORBIC ACID:

Serious 71.7%Non-Serious 28.3%

The FDA classifies an adverse event as “serious” if it results in death, hospitalization, disability, congenital anomaly, or requires intervention to prevent permanent damage.

Demographics Breakdown

Reports by Sex

Female13,468 (63.1%)
Male7,866 (36.8%)
Unknown15 (0.1%)

Reports by Age

Age 64413 reports
Age 65387 reports
Age 71374 reports
Age 80371 reports
Age 66362 reports
Age 63361 reports
Age 74356 reports
Age 70353 reports
Age 67343 reports
Age 68343 reports
Age 69333 reports
Age 73332 reports
Age 77330 reports
Age 59329 reports
Age 72327 reports
Age 75323 reports
Age 78314 reports
Age 44313 reports
Age 60311 reports
Age 58309 reports

Demographics reflect voluntary FDA adverse event reporting patterns and may not represent the full patient population.

Frequently Asked Questions

How many FDA adverse event reports are associated with ASCORBIC ACID?

This profile reflects 77,147 FDA FAERS reports that mention ASCORBIC ACID. Reporting is voluntary and does not prove that the drug caused any listed event.

Which adverse reactions are most often listed for ASCORBIC ACID?

Frequently reported terms in FAERS include FATIGUE, PAIN, NAUSEA, DIARRHOEA, HEADACHE, DRUG INEFFECTIVE. Rankings reflect reporting volume in this dataset, not confirmed side effect rates in the general population.

Who manufactures ASCORBIC ACID?

Labeling and FAERS entries often list McGuff Pharmaceuticals, Inc. in connection with ASCORBIC ACID. Always verify the specific product and NDC with your pharmacist.

Important Disclaimer: This content is generated by AI analysis of FDA adverse event reports and is provided for informational purposes only. It is not medical advice. Adverse event reports submitted to the FDA do not prove that a medication caused the reported side effect. Always consult your healthcare provider before starting, stopping, or changing any medication. If you experience a serious side effect, contact your doctor or call 911 immediately.