AVAPRITINIB

N/A

Manufactured by Blueprint Medicines Corporation

25,335 FDA adverse event reports analyzed

Last updated: 2026-04-14

About AVAPRITINIB

AVAPRITINIB is a medication tracked in the FDA Adverse Event Reporting System (FAERS), manufactured by Blueprint Medicines Corporation. The most commonly reported adverse reactions for AVAPRITINIB include FATIGUE, OFF LABEL USE, NAUSEA, DIARRHOEA, SWELLING FACE. This page provides a comprehensive breakdown of reported side effects, safety signals, patient demographics, and AI-powered safety analysis for AVAPRITINIB.

Top Adverse Reactions

FATIGUE1,594 reports
OFF LABEL USE1,218 reports
NAUSEA1,104 reports
DIARRHOEA937 reports
SWELLING FACE498 reports
DIZZINESS492 reports
MEMORY IMPAIRMENT490 reports
HEADACHE489 reports
VOMITING482 reports
ASTHENIA443 reports
PLATELET COUNT DECREASED437 reports
PERIPHERAL SWELLING434 reports
RASH431 reports
LACRIMATION INCREASED413 reports
PRODUCT DOSE OMISSION ISSUE403 reports
DECREASED APPETITE402 reports
EYE SWELLING377 reports
PERIORBITAL SWELLING373 reports
PAIN363 reports
INSOMNIA360 reports
HAIR COLOUR CHANGES357 reports
DRUG INEFFECTIVE325 reports
MALAISE313 reports
FEELING ABNORMAL301 reports
ARTHRALGIA282 reports
ABDOMINAL PAIN UPPER278 reports
PRURITUS276 reports
HAEMOGLOBIN DECREASED269 reports
BRAIN FOG268 reports
ALOPECIA263 reports
CONSTIPATION259 reports
ANAEMIA254 reports
TRYPTASE INCREASED254 reports
WHITE BLOOD CELL COUNT DECREASED252 reports
SWELLING249 reports
CONDITION AGGRAVATED242 reports
DEATH235 reports
COVID 19226 reports
ABDOMINAL DISCOMFORT224 reports
COGNITIVE DISORDER221 reports
WEIGHT INCREASED219 reports
ADVERSE DRUG REACTION210 reports
PAIN IN EXTREMITY207 reports
ILLNESS203 reports
DYSPNOEA201 reports
FALL199 reports
FLUID RETENTION194 reports
BACK PAIN193 reports
CONFUSIONAL STATE192 reports
WEIGHT DECREASED190 reports
INTENTIONAL DOSE OMISSION186 reports
NASOPHARYNGITIS182 reports
BONE PAIN173 reports
SOMNOLENCE167 reports
ANXIETY165 reports
RED BLOOD CELL COUNT DECREASED165 reports
PERIORBITAL OEDEMA162 reports
TASTE DISORDER160 reports
GASTROINTESTINAL DISORDER159 reports
DISEASE PROGRESSION158 reports
ABDOMINAL DISTENSION157 reports
APHASIA157 reports
FACE OEDEMA151 reports
ABDOMINAL PAIN149 reports
OEDEMA148 reports
UNEVALUABLE EVENT146 reports
JOINT SWELLING143 reports
COUGH139 reports
HYPERSENSITIVITY137 reports
OEDEMA PERIPHERAL136 reports
BALANCE DISORDER132 reports
PRODUCT DOSE OMISSION IN ERROR120 reports
DYSPEPSIA116 reports
AMNESIA115 reports
LABORATORY TEST ABNORMAL115 reports
ERYTHEMA114 reports
DRUG INTOLERANCE113 reports
GAIT DISTURBANCE113 reports
DEPRESSION112 reports
HYPOAESTHESIA109 reports
PARAESTHESIA108 reports
URTICARIA108 reports
FLUSHING105 reports
DYSGEUSIA104 reports
BLOOD BILIRUBIN INCREASED103 reports
URINARY TRACT INFECTION103 reports
PHOTOSENSITIVITY REACTION101 reports
SURGERY100 reports
TREMOR99 reports
MUSCLE SPASMS96 reports
PYREXIA96 reports
HYPERTENSION95 reports
BLOOD POTASSIUM DECREASED92 reports
DRY SKIN92 reports
RASH MACULAR91 reports
STRESS91 reports
DYSPHONIA90 reports
VISION BLURRED89 reports
VISUAL IMPAIRMENT89 reports
MUSCULAR WEAKNESS88 reports

Report Outcomes

Out of 10,788 classified reports for AVAPRITINIB:

Serious 28.9%Non-Serious 71.1%

The FDA classifies an adverse event as “serious” if it results in death, hospitalization, disability, congenital anomaly, or requires intervention to prevent permanent damage.

Demographics Breakdown

Reports by Sex

Female5,858 (57.1%)
Male4,402 (42.9%)

Reports by Age

Age 68259 reports
Age 69245 reports
Age 67242 reports
Age 72207 reports
Age 73202 reports
Age 74200 reports
Age 66198 reports
Age 77192 reports
Age 70186 reports
Age 71167 reports
Age 78161 reports
Age 76157 reports
Age 64153 reports
Age 75149 reports
Age 65147 reports
Age 60134 reports
Age 62134 reports
Age 58130 reports
Age 63130 reports
Age 50128 reports

Demographics reflect voluntary FDA adverse event reporting patterns and may not represent the full patient population.

Frequently Asked Questions

How many FDA adverse event reports are associated with AVAPRITINIB?

This profile reflects 25,335 FDA FAERS reports that mention AVAPRITINIB. Reporting is voluntary and does not prove that the drug caused any listed event.

Which adverse reactions are most often listed for AVAPRITINIB?

Frequently reported terms in FAERS include FATIGUE, OFF LABEL USE, NAUSEA, DIARRHOEA, SWELLING FACE, DIZZINESS. Rankings reflect reporting volume in this dataset, not confirmed side effect rates in the general population.

Who manufactures AVAPRITINIB?

Labeling and FAERS entries often list Blueprint Medicines Corporation in connection with AVAPRITINIB. Always verify the specific product and NDC with your pharmacist.

Important Disclaimer: This content is generated by AI analysis of FDA adverse event reports and is provided for informational purposes only. It is not medical advice. Adverse event reports submitted to the FDA do not prove that a medication caused the reported side effect. Always consult your healthcare provider before starting, stopping, or changing any medication. If you experience a serious side effect, contact your doctor or call 911 immediately.