BRIMONIDINE

N/A

Manufactured by Padagis Israel Pharmaceuticals Ltd

11,162 FDA adverse event reports analyzed

Last updated: 2026-04-14

About BRIMONIDINE

BRIMONIDINE is a medication tracked in the FDA Adverse Event Reporting System (FAERS), manufactured by Padagis Israel Pharmaceuticals Ltd. The most commonly reported adverse reactions for BRIMONIDINE include TREATMENT FAILURE, DRUG INEFFECTIVE, HYPERSENSITIVITY, OFF LABEL USE, FATIGUE. This page provides a comprehensive breakdown of reported side effects, safety signals, patient demographics, and AI-powered safety analysis for BRIMONIDINE.

Top Adverse Reactions

TREATMENT FAILURE2,756 reports
DRUG INEFFECTIVE553 reports
HYPERSENSITIVITY440 reports
OFF LABEL USE261 reports
FATIGUE240 reports
INTRAOCULAR PRESSURE INCREASED224 reports
DIZZINESS183 reports
EYE IRRITATION180 reports
OCULAR HYPERAEMIA179 reports
DIARRHOEA166 reports
VISION BLURRED166 reports
EYE PAIN165 reports
NAUSEA164 reports
FALL153 reports
HEADACHE151 reports
DEATH142 reports
DRUG HYPERSENSITIVITY138 reports
DYSPNOEA138 reports
GLAUCOMA138 reports
VISUAL IMPAIRMENT119 reports
PNEUMONIA101 reports
PAIN97 reports
PRURITUS97 reports
ASTHENIA96 reports
RASH95 reports
PRODUCT DOSE OMISSION ISSUE94 reports
COUGH93 reports
ACUTE KIDNEY INJURY90 reports
VOMITING89 reports
CONDITION AGGRAVATED87 reports
CHRONIC KIDNEY DISEASE81 reports
WEIGHT DECREASED77 reports
URINARY TRACT INFECTION76 reports
MALAISE75 reports
ARTHRALGIA74 reports
CATARACT74 reports
SOMNOLENCE74 reports
DRY EYE73 reports
CONFUSIONAL STATE72 reports
CONSTIPATION69 reports
EYE PRURITUS69 reports
HYPOTENSION69 reports
TOXICITY TO VARIOUS AGENTS69 reports
PERIPHERAL SWELLING68 reports
DECREASED APPETITE67 reports
RENAL FAILURE66 reports
PAIN IN EXTREMITY65 reports
VISUAL ACUITY REDUCED64 reports
DRUG INTOLERANCE60 reports
INSOMNIA60 reports
PYREXIA60 reports
ERYTHEMA59 reports
GAIT DISTURBANCE59 reports
DRY MOUTH57 reports
HYPERTENSION57 reports
CORNEAL OEDEMA56 reports
ANAEMIA54 reports
PRODUCT USE IN UNAPPROVED INDICATION54 reports
BACK PAIN51 reports
DEPRESSION51 reports
ATRIAL FIBRILLATION49 reports
BLOOD PRESSURE INCREASED49 reports
BLINDNESS47 reports
LACRIMATION INCREASED46 reports
ABDOMINAL PAIN45 reports
ASTHMA45 reports
PARAESTHESIA45 reports
INCORRECT DOSE ADMINISTERED44 reports
TREMOR44 reports
BLINDNESS UNILATERAL43 reports
BRADYCARDIA43 reports
HALLUCINATION43 reports
THERAPY NON RESPONDER43 reports
BALANCE DISORDER42 reports
EYE DISORDER42 reports
EYE INFLAMMATION42 reports
ABDOMINAL PAIN UPPER41 reports
ANXIETY41 reports
PRODUCT USE ISSUE41 reports
WEIGHT INCREASED41 reports
LOSS OF CONSCIOUSNESS40 reports
MEMORY IMPAIRMENT40 reports
PRODUCT QUALITY ISSUE40 reports
UVEITIS40 reports
ALOPECIA39 reports
HAEMOGLOBIN DECREASED39 reports
NASOPHARYNGITIS39 reports
ABDOMINAL DISCOMFORT37 reports
DEHYDRATION37 reports
CONJUNCTIVITIS36 reports
COVID 1935 reports
INFLAMMATION35 reports
OEDEMA PERIPHERAL35 reports
SEPSIS35 reports
CEREBROVASCULAR ACCIDENT34 reports
CHILLS34 reports
INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION34 reports
MACULAR OEDEMA34 reports
OCULAR SURFACE DISEASE34 reports
PHOTOPHOBIA34 reports

Report Outcomes

Out of 7,411 classified reports for BRIMONIDINE:

Serious 38.0%Non-Serious 62.0%

The FDA classifies an adverse event as “serious” if it results in death, hospitalization, disability, congenital anomaly, or requires intervention to prevent permanent damage.

Demographics Breakdown

Reports by Sex

Female3,946 (55.8%)
Male3,098 (43.8%)
Unknown23 (0.3%)

Reports by Age

Age 70111 reports
Age 7197 reports
Age 7494 reports
Age 7390 reports
Age 7889 reports
Age 7587 reports
Age 7687 reports
Age 7987 reports
Age 8386 reports
Age 8284 reports
Age 7281 reports
Age 7781 reports
Age 8073 reports
Age 6871 reports
Age 8571 reports
Age 6470 reports
Age 6969 reports
Age 8169 reports
Age 6666 reports
Age 6163 reports

Demographics reflect voluntary FDA adverse event reporting patterns and may not represent the full patient population.

Frequently Asked Questions

How many FDA adverse event reports are associated with BRIMONIDINE?

This profile reflects 11,162 FDA FAERS reports that mention BRIMONIDINE. Reporting is voluntary and does not prove that the drug caused any listed event.

Which adverse reactions are most often listed for BRIMONIDINE?

Frequently reported terms in FAERS include TREATMENT FAILURE, DRUG INEFFECTIVE, HYPERSENSITIVITY, OFF LABEL USE, FATIGUE, INTRAOCULAR PRESSURE INCREASED. Rankings reflect reporting volume in this dataset, not confirmed side effect rates in the general population.

Who manufactures BRIMONIDINE?

Labeling and FAERS entries often list Padagis Israel Pharmaceuticals Ltd in connection with BRIMONIDINE. Always verify the specific product and NDC with your pharmacist.

Important Disclaimer: This content is generated by AI analysis of FDA adverse event reports and is provided for informational purposes only. It is not medical advice. Adverse event reports submitted to the FDA do not prove that a medication caused the reported side effect. Always consult your healthcare provider before starting, stopping, or changing any medication. If you experience a serious side effect, contact your doctor or call 911 immediately.