BUMETANIDE

N/A

Manufactured by Validus Pharmaceuticals LLC

57,117 FDA adverse event reports analyzed

Last updated: 2026-04-14

About BUMETANIDE

BUMETANIDE is a medication tracked in the FDA Adverse Event Reporting System (FAERS), manufactured by Validus Pharmaceuticals LLC. The most commonly reported adverse reactions for BUMETANIDE include DYSPNOEA, ACUTE KIDNEY INJURY, DEATH, FATIGUE, DIARRHOEA. This page provides a comprehensive breakdown of reported side effects, safety signals, patient demographics, and AI-powered safety analysis for BUMETANIDE.

Top Adverse Reactions

DYSPNOEA2,495 reports
ACUTE KIDNEY INJURY1,657 reports
DEATH1,641 reports
FATIGUE1,638 reports
DIARRHOEA1,474 reports
NAUSEA1,454 reports
DIZZINESS1,210 reports
HEADACHE1,144 reports
RENAL FAILURE1,134 reports
PNEUMONIA1,086 reports
ASTHENIA1,043 reports
PAIN1,008 reports
HYPOTENSION998 reports
CARDIAC FAILURE CONGESTIVE952 reports
CHRONIC KIDNEY DISEASE894 reports
FALL893 reports
VOMITING853 reports
OEDEMA PERIPHERAL834 reports
DRUG INEFFECTIVE824 reports
MALAISE818 reports
OFF LABEL USE797 reports
COUGH744 reports
FLUID RETENTION741 reports
PERIPHERAL SWELLING737 reports
ANAEMIA709 reports
WEIGHT INCREASED687 reports
CARDIAC FAILURE684 reports
WEIGHT DECREASED653 reports
ARTHRALGIA639 reports
DEHYDRATION634 reports
CHEST PAIN611 reports
CONDITION AGGRAVATED603 reports
ATRIAL FIBRILLATION589 reports
DECREASED APPETITE550 reports
PAIN IN EXTREMITY548 reports
ANXIETY547 reports
RASH538 reports
BACK PAIN533 reports
PRURITUS527 reports
CONFUSIONAL STATE526 reports
RENAL IMPAIRMENT511 reports
GASTROINTESTINAL HAEMORRHAGE507 reports
URINARY TRACT INFECTION492 reports
PYREXIA488 reports
INSOMNIA477 reports
CONSTIPATION476 reports
OEDEMA459 reports
HAEMOGLOBIN DECREASED450 reports
FEELING ABNORMAL446 reports
MYOCARDIAL INFARCTION437 reports
END STAGE RENAL DISEASE420 reports
DRUG INTERACTION409 reports
HYPERTENSION406 reports
SEPSIS393 reports
RENAL FAILURE ACUTE383 reports
BLOOD CREATININE INCREASED373 reports
ABDOMINAL PAIN UPPER368 reports
PULMONARY HYPERTENSION367 reports
EPISTAXIS366 reports
BLOOD GLUCOSE INCREASED359 reports
ABDOMINAL DISTENSION358 reports
ABDOMINAL PAIN356 reports
PULMONARY OEDEMA349 reports
CELLULITIS345 reports
OXYGEN SATURATION DECREASED340 reports
MYALGIA337 reports
PALPITATIONS336 reports
DYSPNOEA EXERTIONAL334 reports
PRODUCT DOSE OMISSION ISSUE334 reports
LOSS OF CONSCIOUSNESS329 reports
PLEURAL EFFUSION326 reports
HOSPITALISATION321 reports
GAIT DISTURBANCE320 reports
ABDOMINAL DISCOMFORT319 reports
RESPIRATORY FAILURE319 reports
HYPERKALAEMIA318 reports
DEPRESSION316 reports
SYNCOPE306 reports
CONTUSION302 reports
SOMNOLENCE300 reports
TREMOR297 reports
SWELLING293 reports
CHRONIC OBSTRUCTIVE PULMONARY DISEASE291 reports
MUSCLE SPASMS284 reports
CARDIAC ARREST278 reports
COVID 19273 reports
CARDIAC DISORDER272 reports
HEART RATE INCREASED272 reports
THROMBOCYTOPENIA268 reports
INTERNATIONAL NORMALISED RATIO INCREASED267 reports
BLOOD PRESSURE DECREASED265 reports
FLUID OVERLOAD265 reports
RENAL INJURY262 reports
MUSCULAR WEAKNESS258 reports
HYPOXIA255 reports
BRADYCARDIA250 reports
HYPOKALAEMIA249 reports
PULMONARY ARTERIAL HYPERTENSION246 reports
PLATELET COUNT DECREASED237 reports
MEMORY IMPAIRMENT236 reports

Report Outcomes

Out of 24,992 classified reports for BUMETANIDE:

Serious 77.7%Non-Serious 22.3%

The FDA classifies an adverse event as “serious” if it results in death, hospitalization, disability, congenital anomaly, or requires intervention to prevent permanent damage.

Demographics Breakdown

Reports by Sex

Female12,979 (55.8%)
Male10,254 (44.1%)
Unknown40 (0.2%)

Reports by Age

Age 73528 reports
Age 75524 reports
Age 78517 reports
Age 72504 reports
Age 68501 reports
Age 76500 reports
Age 71492 reports
Age 77491 reports
Age 74488 reports
Age 79471 reports
Age 69467 reports
Age 63453 reports
Age 81448 reports
Age 65443 reports
Age 70436 reports
Age 64432 reports
Age 67430 reports
Age 82406 reports
Age 80402 reports
Age 83383 reports

Demographics reflect voluntary FDA adverse event reporting patterns and may not represent the full patient population.

Frequently Asked Questions

How many FDA adverse event reports are associated with BUMETANIDE?

This profile reflects 57,117 FDA FAERS reports that mention BUMETANIDE. Reporting is voluntary and does not prove that the drug caused any listed event.

Which adverse reactions are most often listed for BUMETANIDE?

Frequently reported terms in FAERS include DYSPNOEA, ACUTE KIDNEY INJURY, DEATH, FATIGUE, DIARRHOEA, NAUSEA. Rankings reflect reporting volume in this dataset, not confirmed side effect rates in the general population.

Who manufactures BUMETANIDE?

Labeling and FAERS entries often list Validus Pharmaceuticals LLC in connection with BUMETANIDE. Always verify the specific product and NDC with your pharmacist.

Important Disclaimer: This content is generated by AI analysis of FDA adverse event reports and is provided for informational purposes only. It is not medical advice. Adverse event reports submitted to the FDA do not prove that a medication caused the reported side effect. Always consult your healthcare provider before starting, stopping, or changing any medication. If you experience a serious side effect, contact your doctor or call 911 immediately.