CHLORPHENIRAMINE MALEATE

N/A

Manufactured by Rite Aid Corporation

15,638 FDA adverse event reports analyzed

Last updated: 2026-04-15

About CHLORPHENIRAMINE MALEATE

CHLORPHENIRAMINE MALEATE is a medication tracked in the FDA Adverse Event Reporting System (FAERS), manufactured by Rite Aid Corporation. The most commonly reported adverse reactions for CHLORPHENIRAMINE MALEATE include NAUSEA, DIARRHOEA, OFF LABEL USE, FATIGUE, DYSPNOEA. This page provides a comprehensive breakdown of reported side effects, safety signals, patient demographics, and AI-powered safety analysis for CHLORPHENIRAMINE MALEATE.

Top Adverse Reactions

NAUSEA601 reports
DIARRHOEA568 reports
OFF LABEL USE506 reports
FATIGUE468 reports
DYSPNOEA417 reports
PYREXIA383 reports
VOMITING375 reports
NEUTROPENIA292 reports
HEADACHE274 reports
PNEUMONIA271 reports
COUGH259 reports
NEUROPATHY PERIPHERAL256 reports
RASH254 reports
PRURITUS247 reports
DEATH241 reports
DIZZINESS238 reports
CONSTIPATION232 reports
FEBRILE NEUTROPENIA226 reports
DISEASE PROGRESSION216 reports
ABDOMINAL PAIN193 reports
ANAEMIA191 reports
ASTHENIA189 reports
PLATELET COUNT DECREASED188 reports
DECREASED APPETITE187 reports
ALOPECIA183 reports
MALAISE182 reports
DRUG INEFFECTIVE176 reports
PAIN169 reports
BACK PAIN166 reports
CONDITION AGGRAVATED164 reports
COVID 19161 reports
HYPOTENSION158 reports
ERYTHEMA157 reports
PRODUCT USE IN UNAPPROVED INDICATION157 reports
THROMBOCYTOPENIA157 reports
CHEST PAIN154 reports
MUCOSAL INFLAMMATION149 reports
FLUSHING147 reports
INFUSION RELATED REACTION146 reports
DRUG HYPERSENSITIVITY143 reports
SEIZURE142 reports
LOWER RESPIRATORY TRACT INFECTION140 reports
SOMNOLENCE137 reports
ARTHRALGIA133 reports
OVERDOSE133 reports
TACHYCARDIA132 reports
WEIGHT DECREASED131 reports
INSOMNIA130 reports
CHEST DISCOMFORT128 reports
DYSPEPSIA126 reports
URINARY TRACT INFECTION125 reports
URTICARIA124 reports
HYPERSENSITIVITY120 reports
SEPSIS120 reports
TOXICITY TO VARIOUS AGENTS119 reports
ALANINE AMINOTRANSFERASE INCREASED110 reports
CELLULITIS110 reports
ABDOMINAL PAIN UPPER108 reports
NASOPHARYNGITIS106 reports
ANXIETY105 reports
PAIN IN EXTREMITY104 reports
PARAESTHESIA103 reports
HYPERTENSION102 reports
NEUTROPHIL COUNT DECREASED100 reports
FALL98 reports
WHITE BLOOD CELL COUNT DECREASED98 reports
HYPONATRAEMIA94 reports
MYALGIA92 reports
ANAPHYLACTIC REACTION90 reports
HYPOKALAEMIA90 reports
SWELLING FACE90 reports
CONFUSIONAL STATE89 reports
INFECTION88 reports
LEUKOPENIA88 reports
OEDEMA PERIPHERAL88 reports
PALPITATIONS87 reports
OROPHARYNGEAL PAIN85 reports
INCORRECT DOSE ADMINISTERED84 reports
CHILLS81 reports
PULMONARY EMBOLISM81 reports
TREMOR81 reports
PLEURAL EFFUSION79 reports
ACUTE KIDNEY INJURY78 reports
WEIGHT INCREASED78 reports
ASTHMA76 reports
INTENTIONAL PRODUCT USE ISSUE76 reports
AFFECTIVE DISORDER75 reports
LYMPHOCYTE COUNT DECREASED75 reports
OXYGEN SATURATION DECREASED75 reports
EXTRAPYRAMIDAL DISORDER74 reports
GENERAL PHYSICAL HEALTH DETERIORATION74 reports
PRODUCT USE ISSUE74 reports
PERIPHERAL SWELLING73 reports
SLEEP DISORDER73 reports
DRUG INTERACTION72 reports
HAEMOGLOBIN DECREASED71 reports
MUSCULAR WEAKNESS71 reports
PANCYTOPENIA71 reports
BLOOD PRESSURE INCREASED70 reports
EJECTION FRACTION DECREASED70 reports

Report Outcomes

Out of 6,220 classified reports for CHLORPHENIRAMINE MALEATE:

Serious 85.8%Non-Serious 14.2%

The FDA classifies an adverse event as “serious” if it results in death, hospitalization, disability, congenital anomaly, or requires intervention to prevent permanent damage.

Demographics Breakdown

Reports by Sex

Female3,332 (59.6%)
Male2,260 (40.4%)
Unknown3 (0.1%)

Reports by Age

Age 59168 reports
Age 54122 reports
Age 60119 reports
Age 66115 reports
Age 75112 reports
Age 67110 reports
Age 57108 reports
Age 55106 reports
Age 74103 reports
Age 56102 reports
Age 62102 reports
Age 72102 reports
Age 6195 reports
Age 4591 reports
Age 5891 reports
Age 5290 reports
Age 6990 reports
Age 7390 reports
Age 7188 reports
Age 5387 reports

Demographics reflect voluntary FDA adverse event reporting patterns and may not represent the full patient population.

Frequently Asked Questions

How many FDA adverse event reports are associated with CHLORPHENIRAMINE MALEATE?

This profile reflects 15,638 FDA FAERS reports that mention CHLORPHENIRAMINE MALEATE. Reporting is voluntary and does not prove that the drug caused any listed event.

Which adverse reactions are most often listed for CHLORPHENIRAMINE MALEATE?

Frequently reported terms in FAERS include NAUSEA, DIARRHOEA, OFF LABEL USE, FATIGUE, DYSPNOEA, PYREXIA. Rankings reflect reporting volume in this dataset, not confirmed side effect rates in the general population.

Who manufactures CHLORPHENIRAMINE MALEATE?

Labeling and FAERS entries often list Rite Aid Corporation in connection with CHLORPHENIRAMINE MALEATE. Always verify the specific product and NDC with your pharmacist.

Important Disclaimer: This content is generated by AI analysis of FDA adverse event reports and is provided for informational purposes only. It is not medical advice. Adverse event reports submitted to the FDA do not prove that a medication caused the reported side effect. Always consult your healthcare provider before starting, stopping, or changing any medication. If you experience a serious side effect, contact your doctor or call 911 immediately.