CLONIDINE HYDROCHLORIDE

N/A

Manufactured by NextWave Pharmaceuticals, Inc

24,180 FDA adverse event reports analyzed

Last updated: 2026-04-15

About CLONIDINE HYDROCHLORIDE

CLONIDINE HYDROCHLORIDE is a medication tracked in the FDA Adverse Event Reporting System (FAERS), manufactured by NextWave Pharmaceuticals, Inc. The most commonly reported adverse reactions for CLONIDINE HYDROCHLORIDE include HYPERTENSION, HEADACHE, FATIGUE, OFF LABEL USE, PAIN. This page provides a comprehensive breakdown of reported side effects, safety signals, patient demographics, and AI-powered safety analysis for CLONIDINE HYDROCHLORIDE.

Top Adverse Reactions

HYPERTENSION678 reports
HEADACHE628 reports
FATIGUE581 reports
OFF LABEL USE581 reports
PAIN557 reports
DRUG INEFFECTIVE488 reports
HYPERSENSITIVITY456 reports
NAUSEA418 reports
INFUSION RELATED REACTION385 reports
HEPATIC ENZYME INCREASED377 reports
JOINT SWELLING362 reports
DYSPNOEA360 reports
RASH354 reports
DIARRHOEA330 reports
RHEUMATOID ARTHRITIS319 reports
VOMITING318 reports
DIZZINESS317 reports
PYREXIA317 reports
UPPER RESPIRATORY TRACT INFECTION314 reports
PRESCRIBED OVERDOSE309 reports
INFECTION305 reports
PRODUCT USE ISSUE297 reports
WEIGHT DECREASED295 reports
OVERDOSE285 reports
ARTHRALGIA282 reports
ASTHMA275 reports
HYPERHIDROSIS259 reports
PSORIASIS255 reports
CONSTIPATION253 reports
PNEUMONIA252 reports
PRURITUS248 reports
DECREASED APPETITE243 reports
HYPOAESTHESIA243 reports
PRODUCT DOSE OMISSION ISSUE243 reports
WEIGHT INCREASED243 reports
PAIN IN EXTREMITY242 reports
ANXIETY240 reports
DRUG HYPERSENSITIVITY239 reports
BACK PAIN233 reports
NASOPHARYNGITIS233 reports
DRUG INTOLERANCE224 reports
IMMUNODEFICIENCY223 reports
FOOD ALLERGY218 reports
CONDITION AGGRAVATED217 reports
PERIPHERAL SWELLING217 reports
DEPRESSION214 reports
CHEST PAIN204 reports
TREATMENT FAILURE204 reports
ABDOMINAL DISCOMFORT202 reports
BLOOD PRESSURE INCREASED202 reports
EXPOSURE DURING PREGNANCY201 reports
HYPERCHOLESTEROLAEMIA199 reports
INTENTIONAL PRODUCT MISUSE197 reports
ALOPECIA196 reports
ERYTHEMA195 reports
HYPOTENSION193 reports
URTICARIA192 reports
GAIT DISTURBANCE190 reports
CONTUSION186 reports
OEDEMA PERIPHERAL185 reports
FIBROMYALGIA184 reports
ASTHENIA182 reports
MALAISE181 reports
OSTEOARTHRITIS181 reports
TYPE 2 DIABETES MELLITUS181 reports
FALL180 reports
INSOMNIA179 reports
VISUAL IMPAIRMENT179 reports
GENERAL PHYSICAL HEALTH DETERIORATION178 reports
IMPAIRED HEALING176 reports
SINUSITIS174 reports
DEATH169 reports
INJURY168 reports
HELICOBACTER INFECTION167 reports
JOINT STIFFNESS166 reports
FLUID RETENTION165 reports
IRRITABLE BOWEL SYNDROME162 reports
MUSCULOSKELETAL STIFFNESS161 reports
OSTEOPOROSIS161 reports
JOINT DISLOCATION160 reports
MUSCULAR WEAKNESS160 reports
OEDEMA160 reports
WHEEZING160 reports
BURSITIS159 reports
CONFUSIONAL STATE159 reports
MOBILITY DECREASED158 reports
CONTRAINDICATED PRODUCT ADMINISTERED157 reports
JOINT RANGE OF MOTION DECREASED155 reports
PRODUCT USE IN UNAPPROVED INDICATION153 reports
PRESCRIBED UNDERDOSE152 reports
WOUND INFECTION152 reports
WOUND151 reports
BLISTER150 reports
MEMORY IMPAIRMENT150 reports
COUGH149 reports
DYSPEPSIA146 reports
EAR INFECTION146 reports
THROMBOCYTOPENIA146 reports
GLOSSODYNIA145 reports
PERICARDITIS145 reports

Report Outcomes

Out of 5,066 classified reports for CLONIDINE HYDROCHLORIDE:

Serious 68.5%Non-Serious 31.5%

The FDA classifies an adverse event as “serious” if it results in death, hospitalization, disability, congenital anomaly, or requires intervention to prevent permanent damage.

Demographics Breakdown

Reports by Sex

Female3,028 (66.8%)
Male1,494 (33.0%)
Unknown11 (0.2%)

Reports by Age

Age 58151 reports
Age 7370 reports
Age 6767 reports
Age 3663 reports
Age 7463 reports
Age 6860 reports
Age 6359 reports
Age 6258 reports
Age 6657 reports
Age 7054 reports
Age 6453 reports
Age 5552 reports
Age 5651 reports
Age 6149 reports
Age 5048 reports
Age 5748 reports
Age 6948 reports
Age 4346 reports
Age 6045 reports
Age 6543 reports

Demographics reflect voluntary FDA adverse event reporting patterns and may not represent the full patient population.

Frequently Asked Questions

How many FDA adverse event reports are associated with CLONIDINE HYDROCHLORIDE?

This profile reflects 24,180 FDA FAERS reports that mention CLONIDINE HYDROCHLORIDE. Reporting is voluntary and does not prove that the drug caused any listed event.

Which adverse reactions are most often listed for CLONIDINE HYDROCHLORIDE?

Frequently reported terms in FAERS include HYPERTENSION, HEADACHE, FATIGUE, OFF LABEL USE, PAIN, DRUG INEFFECTIVE. Rankings reflect reporting volume in this dataset, not confirmed side effect rates in the general population.

Who manufactures CLONIDINE HYDROCHLORIDE?

Labeling and FAERS entries often list NextWave Pharmaceuticals, Inc in connection with CLONIDINE HYDROCHLORIDE. Always verify the specific product and NDC with your pharmacist.

Important Disclaimer: This content is generated by AI analysis of FDA adverse event reports and is provided for informational purposes only. It is not medical advice. Adverse event reports submitted to the FDA do not prove that a medication caused the reported side effect. Always consult your healthcare provider before starting, stopping, or changing any medication. If you experience a serious side effect, contact your doctor or call 911 immediately.