DAPTOMYCIN

N/A

Manufactured by APOTEX CORP.

14,068 FDA adverse event reports analyzed

Last updated: 2026-04-14

About DAPTOMYCIN

DAPTOMYCIN is a medication tracked in the FDA Adverse Event Reporting System (FAERS), manufactured by APOTEX CORP.. The most commonly reported adverse reactions for DAPTOMYCIN include DRUG INEFFECTIVE, OFF LABEL USE, ACUTE KIDNEY INJURY, PYREXIA, EOSINOPHILIC PNEUMONIA. This page provides a comprehensive breakdown of reported side effects, safety signals, patient demographics, and AI-powered safety analysis for DAPTOMYCIN.

Top Adverse Reactions

DRUG INEFFECTIVE703 reports
OFF LABEL USE652 reports
ACUTE KIDNEY INJURY527 reports
PYREXIA459 reports
EOSINOPHILIC PNEUMONIA418 reports
RHABDOMYOLYSIS336 reports
EOSINOPHILIA328 reports
BLOOD CREATINE PHOSPHOKINASE INCREASED327 reports
DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS322 reports
NEUTROPENIA270 reports
RASH255 reports
PRODUCT USE IN UNAPPROVED INDICATION251 reports
THROMBOCYTOPENIA250 reports
INTERSTITIAL LUNG DISEASE231 reports
PNEUMONITIS224 reports
DRUG INTERACTION217 reports
DYSPNOEA215 reports
CHILLS207 reports
SEPSIS205 reports
PNEUMONIA203 reports
AGRANULOCYTOSIS193 reports
HEPATIC CYTOLYSIS179 reports
NAUSEA172 reports
DEATH161 reports
CONDITION AGGRAVATED157 reports
CHOLESTASIS150 reports
RESPIRATORY FAILURE147 reports
SEPTIC SHOCK147 reports
STAPHYLOCOCCAL INFECTION141 reports
DRUG HYPERSENSITIVITY138 reports
MULTIPLE ORGAN DYSFUNCTION SYNDROME135 reports
EOSINOPHILIC PNEUMONIA ACUTE134 reports
PATHOGEN RESISTANCE134 reports
LEUKOPENIA133 reports
RASH MACULO PAPULAR133 reports
FEBRILE NEUTROPENIA130 reports
DRUG RESISTANCE128 reports
PANCYTOPENIA126 reports
TREATMENT FAILURE126 reports
HYPOTENSION122 reports
BACTERAEMIA117 reports
MALAISE114 reports
RENAL FAILURE113 reports
ANAEMIA112 reports
TOXIC EPIDERMAL NECROLYSIS112 reports
DIARRHOEA110 reports
DRUG INEFFECTIVE FOR UNAPPROVED INDICATION110 reports
STAPHYLOCOCCAL BACTERAEMIA109 reports
TREMOR109 reports
ASTHENIA106 reports
CONFUSIONAL STATE106 reports
LUNG DISORDER106 reports
PRURITUS106 reports
FATIGUE105 reports
CANDIDA INFECTION100 reports
ENCEPHALOPATHY95 reports
RENAL IMPAIRMENT93 reports
VOMITING93 reports
INFECTION92 reports
ERYTHEMA88 reports
BLOOD CREATININE INCREASED85 reports
MYALGIA83 reports
PAIN80 reports
PLEURAL EFFUSION78 reports
ENTEROCOCCAL INFECTION77 reports
URTICARIA75 reports
LOWER RESPIRATORY TRACT INFECTION73 reports
ARTHRALGIA69 reports
HYPERSENSITIVITY68 reports
ACUTE RESPIRATORY DISTRESS SYNDROME65 reports
ACUTE RESPIRATORY FAILURE65 reports
ATRIAL FIBRILLATION65 reports
HYPERKALAEMIA65 reports
LACTIC ACIDOSIS65 reports
PLATELET COUNT DECREASED65 reports
OSTEOMYELITIS64 reports
COUGH63 reports
TACHYCARDIA63 reports
THERAPY NON RESPONDER63 reports
CHEST PAIN62 reports
HYPOXIA62 reports
HEADACHE61 reports
STEVENS JOHNSON SYNDROME61 reports
TUBULOINTERSTITIAL NEPHRITIS59 reports
C REACTIVE PROTEIN INCREASED58 reports
DISEASE PROGRESSION57 reports
HAEMOGLOBIN DECREASED57 reports
ACUTE GENERALISED EXANTHEMATOUS PUSTULOSIS55 reports
PRODUCT USE ISSUE55 reports
ABDOMINAL PAIN54 reports
DIZZINESS54 reports
DRUG INDUCED LIVER INJURY54 reports
TOXICITY TO VARIOUS AGENTS54 reports
ASPERGILLUS INFECTION52 reports
SYSTEMIC CANDIDA52 reports
CELLULITIS51 reports
RESPIRATORY DISTRESS50 reports
BACK PAIN49 reports
CARDIAC ARREST49 reports
DRUG ERUPTION49 reports

Report Outcomes

Out of 8,425 classified reports for DAPTOMYCIN:

Serious 92.8%Non-Serious 7.2%

The FDA classifies an adverse event as “serious” if it results in death, hospitalization, disability, congenital anomaly, or requires intervention to prevent permanent damage.

Demographics Breakdown

Reports by Sex

Male4,784 (60.8%)
Female3,075 (39.1%)
Unknown5 (0.1%)

Reports by Age

Age 71231 reports
Age 65222 reports
Age 64203 reports
Age 69198 reports
Age 74198 reports
Age 70193 reports
Age 73193 reports
Age 67184 reports
Age 68179 reports
Age 55178 reports
Age 66175 reports
Age 75175 reports
Age 72166 reports
Age 77163 reports
Age 76159 reports
Age 54153 reports
Age 60152 reports
Age 61151 reports
Age 62150 reports
Age 79148 reports

Demographics reflect voluntary FDA adverse event reporting patterns and may not represent the full patient population.

Frequently Asked Questions

How many FDA adverse event reports are associated with DAPTOMYCIN?

This profile reflects 14,068 FDA FAERS reports that mention DAPTOMYCIN. Reporting is voluntary and does not prove that the drug caused any listed event.

Which adverse reactions are most often listed for DAPTOMYCIN?

Frequently reported terms in FAERS include DRUG INEFFECTIVE, OFF LABEL USE, ACUTE KIDNEY INJURY, PYREXIA, EOSINOPHILIC PNEUMONIA, RHABDOMYOLYSIS. Rankings reflect reporting volume in this dataset, not confirmed side effect rates in the general population.

Who manufactures DAPTOMYCIN?

Labeling and FAERS entries often list APOTEX CORP. in connection with DAPTOMYCIN. Always verify the specific product and NDC with your pharmacist.

Important Disclaimer: This content is generated by AI analysis of FDA adverse event reports and is provided for informational purposes only. It is not medical advice. Adverse event reports submitted to the FDA do not prove that a medication caused the reported side effect. Always consult your healthcare provider before starting, stopping, or changing any medication. If you experience a serious side effect, contact your doctor or call 911 immediately.