DIHYDROERGOTAMINE MESYLATE

N/A

Manufactured by Impel Pharmaceuticals LLC

4,245 FDA adverse event reports analyzed

Last updated: 2026-04-15

About DIHYDROERGOTAMINE MESYLATE

DIHYDROERGOTAMINE MESYLATE is a medication tracked in the FDA Adverse Event Reporting System (FAERS), manufactured by Impel Pharmaceuticals LLC. The most commonly reported adverse reactions for DIHYDROERGOTAMINE MESYLATE include DRUG INEFFECTIVE, NAUSEA, OFF LABEL USE, HYPERHIDROSIS, NIGHTMARE. This page provides a comprehensive breakdown of reported side effects, safety signals, patient demographics, and AI-powered safety analysis for DIHYDROERGOTAMINE MESYLATE.

Top Adverse Reactions

DRUG INEFFECTIVE472 reports
NAUSEA299 reports
OFF LABEL USE290 reports
HYPERHIDROSIS267 reports
NIGHTMARE253 reports
SEDATION253 reports
PRODUCT USE IN UNAPPROVED INDICATION207 reports
NEPHROLITHIASIS171 reports
MIGRAINE98 reports
DYSPNOEA84 reports
NASAL CONGESTION77 reports
HEADACHE59 reports
TREATMENT FAILURE57 reports
COUGH49 reports
DIARRHOEA49 reports
ABDOMINAL PAIN46 reports
WEIGHT DECREASED46 reports
DIZZINESS43 reports
DYSPEPSIA43 reports
EXTRAPYRAMIDAL DISORDER42 reports
DRUG INEFFECTIVE FOR UNAPPROVED INDICATION41 reports
ANURIA40 reports
NEOVASCULARISATION40 reports
PARADOXICAL DRUG REACTION40 reports
FATIGUE38 reports
MALAISE38 reports
PRODUCT USED FOR UNKNOWN INDICATION37 reports
PAIN34 reports
VOMITING30 reports
NASAL DISCOMFORT28 reports
SOMNOLENCE26 reports
ASTHENIA25 reports
FALL25 reports
PARAESTHESIA23 reports
ARTHRALGIA20 reports
PAIN IN EXTREMITY19 reports
PRODUCT USE ISSUE19 reports
CHEST PAIN18 reports
TREMOR18 reports
CONDITION AGGRAVATED17 reports
DEPRESSION17 reports
EYE PAIN17 reports
TACHYCARDIA17 reports
BACK PAIN16 reports
GAIT DISTURBANCE16 reports
GENERAL PHYSICAL HEALTH DETERIORATION16 reports
VISION BLURRED16 reports
FEELING ABNORMAL15 reports
HYPOAESTHESIA15 reports
AMNESIA14 reports
DIPLOPIA14 reports
DRUG INTERACTION14 reports
HOT FLUSH14 reports
HYPERSENSITIVITY14 reports
LIMB DISCOMFORT14 reports
NECK PAIN14 reports
PHOTOPHOBIA14 reports
WEIGHT INCREASED14 reports
BLEPHAROSPASM13 reports
CHEST DISCOMFORT13 reports
CLUSTER HEADACHE13 reports
COORDINATION ABNORMAL13 reports
DYSGEUSIA13 reports
INSOMNIA13 reports
MUSCLE TWITCHING13 reports
NERVOUS SYSTEM DISORDER13 reports
SLEEP DISORDER13 reports
VERTIGO13 reports
BALANCE DISORDER12 reports
COGNITIVE DISORDER12 reports
EPILEPSY12 reports
EYELID PTOSIS12 reports
GENERAL PHYSICAL CONDITION ABNORMAL12 reports
HYPOTENSION12 reports
ILLNESS12 reports
LIGAMENT SPRAIN12 reports
NIGHT SWEATS12 reports
OVERDOSE12 reports
PYREXIA12 reports
AMENORRHOEA11 reports
ANISOCORIA11 reports
ANXIETY11 reports
APATHY11 reports
ASTHENOPIA11 reports
BLINDNESS11 reports
BURNING SENSATION11 reports
CLUMSINESS11 reports
COMMUNICATION DISORDER11 reports
CRYING11 reports
DISABILITY11 reports
DISCOMFORT11 reports
EXOPHTHALMOS11 reports
EXPIRED PRODUCT ADMINISTERED11 reports
EYE INJURY11 reports
EYE MOVEMENT DISORDER11 reports
HETEROPHORIA11 reports
HYPOAESTHESIA EYE11 reports
HYPOCALCAEMIA11 reports
ILL DEFINED DISORDER11 reports
IMPAIRED WORK ABILITY11 reports

Report Outcomes

Out of 1,115 classified reports for DIHYDROERGOTAMINE MESYLATE:

Serious 52.8%Non-Serious 47.2%

The FDA classifies an adverse event as “serious” if it results in death, hospitalization, disability, congenital anomaly, or requires intervention to prevent permanent damage.

Demographics Breakdown

Reports by Sex

Female413 (58.7%)
Male288 (41.0%)
Unknown2 (0.3%)

Reports by Age

Age 53203 reports
Age 5034 reports
Age 6020 reports
Age 3714 reports
Age 3914 reports
Age 4913 reports
Age 3511 reports
Age 5411 reports
Age 429 reports
Age 298 reports
Age 408 reports
Age 367 reports
Age 447 reports
Age 467 reports
Age 477 reports
Age 527 reports
Age 577 reports
Age 587 reports
Age 687 reports
Age 216 reports

Demographics reflect voluntary FDA adverse event reporting patterns and may not represent the full patient population.

Frequently Asked Questions

How many FDA adverse event reports are associated with DIHYDROERGOTAMINE MESYLATE?

This profile reflects 4,245 FDA FAERS reports that mention DIHYDROERGOTAMINE MESYLATE. Reporting is voluntary and does not prove that the drug caused any listed event.

Which adverse reactions are most often listed for DIHYDROERGOTAMINE MESYLATE?

Frequently reported terms in FAERS include DRUG INEFFECTIVE, NAUSEA, OFF LABEL USE, HYPERHIDROSIS, NIGHTMARE, SEDATION. Rankings reflect reporting volume in this dataset, not confirmed side effect rates in the general population.

Who manufactures DIHYDROERGOTAMINE MESYLATE?

Labeling and FAERS entries often list Impel Pharmaceuticals LLC in connection with DIHYDROERGOTAMINE MESYLATE. Always verify the specific product and NDC with your pharmacist.

Important Disclaimer: This content is generated by AI analysis of FDA adverse event reports and is provided for informational purposes only. It is not medical advice. Adverse event reports submitted to the FDA do not prove that a medication caused the reported side effect. Always consult your healthcare provider before starting, stopping, or changing any medication. If you experience a serious side effect, contact your doctor or call 911 immediately.