DORNASE ALFA and INFLUENZA

Overview

INFLUENZA is the #18 most commonly reported adverse reaction for DORNASE ALFA, manufactured by Genentech, Inc.. There are 441 FDA adverse event reports linking DORNASE ALFA to INFLUENZA. This represents approximately 1.5% of all 29,815 adverse event reports for this drug.

Patients taking DORNASE ALFA who experience influenza should discuss this symptom with their healthcare provider to determine whether it may be related to their medication and what alternatives may be available.

Reporting Frequency

INFLUENZA is a less commonly reported adverse event for DORNASE ALFA, but still significant enough to appear in the safety profile.

Other Side Effects of DORNASE ALFA

In addition to influenza, the following adverse reactions have been reported for DORNASE ALFA:

• INFECTIVE PULMONARY EXACERBATION OF CYSTIC FIBROSIS — 2,282 reports
• CYSTIC FIBROSIS — 1,727 reports
• HOSPITALISATION — 1,289 reports
• PNEUMONIA — 1,269 reports
• COUGH — 980 reports
• OFF LABEL USE — 934 reports
• INFECTION — 922 reports
• NO ADVERSE EVENT — 919 reports
• DYSPNOEA — 898 reports
• CONDITION AGGRAVATED — 601 reports

Other Drugs Associated with INFLUENZA

The following drugs have also been linked to influenza in FDA adverse event reports:

Does DORNASE ALFA cause INFLUENZA?

INFLUENZA has been reported as an adverse event in 441 FDA reports for DORNASE ALFA. This does not prove causation, but indicates an association observed in post-market surveillance data.

How common is INFLUENZA with DORNASE ALFA?

INFLUENZA accounts for approximately 1.5% of all adverse event reports for DORNASE ALFA, making it a notable side effect.

What should I do if I experience INFLUENZA while taking DORNASE ALFA?

If you experience influenza while taking DORNASE ALFA, contact your healthcare provider. They can evaluate whether the symptom is related to your medication and discuss potential adjustments to your treatment plan. Do not stop taking prescribed medication without consulting your doctor.

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