DUPILUMAB and PRURITUS

Overview

PRURITUS is the #1 most commonly reported adverse reaction for DUPILUMAB, manufactured by sanofi-aventis U.S. LLC. There are 48,441 FDA adverse event reports linking DUPILUMAB to PRURITUS. This represents approximately 6.2% of all 782,562 adverse event reports for this drug.

Patients taking DUPILUMAB who experience pruritus should discuss this symptom with their healthcare provider to determine whether it may be related to their medication and what alternatives may be available.

Reporting Frequency

PRURITUS48,441 of 782,562 reports

PRURITUS is moderately reported among DUPILUMAB users, representing a notable but not dominant share of adverse events.

Other Side Effects of DUPILUMAB

In addition to pruritus, the following adverse reactions have been reported for DUPILUMAB:

DERMATITIS ATOPIC — 37,675 reports
PRODUCT USE IN UNAPPROVED INDICATION — 36,010 reports
RASH — 33,431 reports
INJECTION SITE PAIN — 30,477 reports
DRUG INEFFECTIVE — 26,034 reports
ECZEMA — 22,304 reports
DRY SKIN — 21,662 reports
PRODUCT DOSE OMISSION ISSUE — 20,789 reports
CONDITION AGGRAVATED — 18,451 reports
ARTHRALGIA — 16,570 reports

Other Drugs Associated with PRURITUS

The following drugs have also been linked to pruritus in FDA adverse event reports:

ACETAMINOPHEN ACETAMINOPHEN 325 MG ACETAMINOPHEN 325MG ACETAMINOPHEN 500 MG ACETAMINOPHEN 500MG ACETAMINOPHEN, ASPIRIN, CAFFEINE ACETAMINOPHEN, DEXTROMETHORPHAN HBR, GUAIFENESIN, PHENYLEPHRINE HCL ACETAMINOPHEN, GUAIFENESIN, AND PHENYLEPHRINE HYDROCHLORIDE ACETAMINOPHEN TABLET EXTENDED RELEASE ADAPALENE ADAPALENE AND BENZOYL PEROXIDE ALCOHOL ANTISEPTIC ALIROCUMAB ALISKIREN HEMIFUMARATE ALLERGY RELIEF ALPELISIB .ALPHA. TOCOPHEROL ACETATE, DL , ASCORBIC ACID, CYANOCOBALAMIN, FOLIC ACID, NIACIN, PYRIDOXINE, RIBOFLAVIN, SODIUM FLUORIDE, THIAMINE MONONITRATE, VITAMIN A AND VITAMIN D ALUMINUM CHLORIDE ALUMINUM HYDROXIDE, MAGNESIUM HYDROXIDE, SIMETHICONE ALUMINUM ZIRCONIUM TETRACHLOROHYDREX GLY

Does DUPILUMAB cause PRURITUS?

PRURITUS has been reported as an adverse event in 48,441 FDA reports for DUPILUMAB. This does not prove causation, but indicates an association observed in post-market surveillance data.

How common is PRURITUS with DUPILUMAB?

PRURITUS accounts for approximately 6.2% of all adverse event reports for DUPILUMAB, making it one of the most commonly reported side effect.

What should I do if I experience PRURITUS while taking DUPILUMAB?

If you experience pruritus while taking DUPILUMAB, contact your healthcare provider. They can evaluate whether the symptom is related to your medication and discuss potential adjustments to your treatment plan. Do not stop taking prescribed medication without consulting your doctor.