HYPERICUM PERFORATUM

N/A

Manufactured by Energique, Inc

666 FDA adverse event reports analyzed

Last updated: 2026-04-15

About HYPERICUM PERFORATUM

HYPERICUM PERFORATUM is a medication tracked in the FDA Adverse Event Reporting System (FAERS), manufactured by Energique, Inc. The most commonly reported adverse reactions for HYPERICUM PERFORATUM include DRUG INTERACTION, ANXIETY, SUICIDAL IDEATION, FATIGUE, PYREXIA. This page provides a comprehensive breakdown of reported side effects, safety signals, patient demographics, and AI-powered safety analysis for HYPERICUM PERFORATUM.

Top Adverse Reactions

DRUG INTERACTION38 reports
ANXIETY22 reports
SUICIDAL IDEATION20 reports
FATIGUE18 reports
PYREXIA17 reports
DEPRESSION16 reports
NAUSEA16 reports
COGNITIVE DISORDER13 reports
INSOMNIA13 reports
SLEEP DISORDER12 reports
ARTHRALGIA11 reports
DEPRESSED MOOD11 reports
PARAESTHESIA10 reports
SEROTONIN SYNDROME10 reports
AGITATION9 reports
ASTHENIA9 reports
TACHYCARDIA9 reports
CONFUSIONAL STATE8 reports
MANIA8 reports
PANIC ATTACK8 reports
PRURITUS8 reports
BLOOD PRESSURE INCREASED7 reports
CONDITION AGGRAVATED7 reports
DIZZINESS7 reports
DRUG INEFFECTIVE7 reports
HYPERHIDROSIS7 reports
MYALGIA7 reports
OFF LABEL USE7 reports
TREMOR7 reports
ABDOMINAL DISCOMFORT6 reports
ATTENTION DEFICIT/HYPERACTIVITY DISORDER6 reports
DISORIENTATION6 reports
DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS6 reports
FALL6 reports
GENERALISED ANXIETY DISORDER6 reports
HOT FLUSH6 reports
HYPERTENSION6 reports
JAUNDICE6 reports
MALAISE6 reports
MEMORY IMPAIRMENT6 reports
NERVOUSNESS6 reports
OCULAR HYPERAEMIA6 reports
PERSONALITY DISORDER6 reports
SELF INJURIOUS IDEATION6 reports
SOCIAL ANXIETY DISORDER6 reports
TENSION6 reports
TOXIC EPIDERMAL NECROLYSIS6 reports
WEIGHT INCREASED6 reports
WOUND6 reports
ABDOMINAL PAIN5 reports
AFFECTIVE DISORDER5 reports
AGGRESSION5 reports
ARTHROPATHY5 reports
BALANCE DISORDER5 reports
BURNING SENSATION5 reports
DIARRHOEA5 reports
DISTURBANCE IN ATTENTION5 reports
HEADACHE5 reports
HEPATIC FAILURE5 reports
HYPOAESTHESIA5 reports
LOSS OF CONSCIOUSNESS5 reports
MIGRAINE5 reports
OEDEMA5 reports
AKATHISIA4 reports
ANAEMIA4 reports
CHEST DISCOMFORT4 reports
CRYING4 reports
DRUG LEVEL DECREASED4 reports
ERYTHEMA4 reports
FEELING ABNORMAL4 reports
HALLUCINATION, VISUAL4 reports
HYPOPROTEINAEMIA4 reports
LEUKOCYTOSIS4 reports
LIBIDO DECREASED4 reports
LIP EROSION4 reports
MENOPAUSAL DISORDER4 reports
MUSCULAR WEAKNESS4 reports
PAIN IN EXTREMITY4 reports
PARANOIA4 reports
POLYNEUROPATHY4 reports
PRODUCT USE ISSUE4 reports
SKIN BURNING SENSATION4 reports
SKIN LESION4 reports
SOMNOLENCE4 reports
SUICIDE ATTEMPT4 reports
VULVOVAGINAL DRYNESS4 reports
ABNORMAL BEHAVIOUR3 reports
ANORGASMIA3 reports
ASCITES3 reports
AUTOIMMUNE HAEMOLYTIC ANAEMIA3 reports
BIPOLAR DISORDER3 reports
BLOOD LACTATE DEHYDROGENASE INCREASED3 reports
BLOOD PRESSURE FLUCTUATION3 reports
CHEST PAIN3 reports
CHROMATURIA3 reports
CONSTIPATION3 reports
DEAFNESS3 reports
DELIRIUM3 reports
DRUG WITHDRAWAL SYNDROME3 reports
DYSPNOEA3 reports

Report Outcomes

Out of 183 classified reports for HYPERICUM PERFORATUM:

Serious 85.2%Non-Serious 14.8%

The FDA classifies an adverse event as “serious” if it results in death, hospitalization, disability, congenital anomaly, or requires intervention to prevent permanent damage.

Demographics Breakdown

Reports by Sex

Female126 (70.4%)
Male53 (29.6%)

Reports by Age

Age 548 reports
Age 287 reports
Age 327 reports
Age 166 reports
Age 426 reports
Age 476 reports
Age 656 reports
Age 836 reports
Age 525 reports
Age 565 reports
Age 585 reports
Age 635 reports
Age 384 reports
Age 253 reports
Age 333 reports
Age 403 reports
Age 453 reports
Age 483 reports
Age 493 reports
Age 573 reports

Demographics reflect voluntary FDA adverse event reporting patterns and may not represent the full patient population.

Frequently Asked Questions

How many FDA adverse event reports are associated with HYPERICUM PERFORATUM?

This profile reflects 666 FDA FAERS reports that mention HYPERICUM PERFORATUM. Reporting is voluntary and does not prove that the drug caused any listed event.

Which adverse reactions are most often listed for HYPERICUM PERFORATUM?

Frequently reported terms in FAERS include DRUG INTERACTION, ANXIETY, SUICIDAL IDEATION, FATIGUE, PYREXIA, DEPRESSION. Rankings reflect reporting volume in this dataset, not confirmed side effect rates in the general population.

Who manufactures HYPERICUM PERFORATUM?

Labeling and FAERS entries often list Energique, Inc in connection with HYPERICUM PERFORATUM. Always verify the specific product and NDC with your pharmacist.

Important Disclaimer: This content is generated by AI analysis of FDA adverse event reports and is provided for informational purposes only. It is not medical advice. Adverse event reports submitted to the FDA do not prove that a medication caused the reported side effect. Always consult your healthcare provider before starting, stopping, or changing any medication. If you experience a serious side effect, contact your doctor or call 911 immediately.