IFOSFAMIDE

N/A

Manufactured by Baxter Healthcare Corporation

42,356 FDA adverse event reports analyzed

Last updated: 2026-04-14

About IFOSFAMIDE

IFOSFAMIDE is a medication tracked in the FDA Adverse Event Reporting System (FAERS), manufactured by Baxter Healthcare Corporation. The most commonly reported adverse reactions for IFOSFAMIDE include OFF LABEL USE, FEBRILE NEUTROPENIA, DISEASE PROGRESSION, NEUTROPENIA, DRUG INEFFECTIVE. This page provides a comprehensive breakdown of reported side effects, safety signals, patient demographics, and AI-powered safety analysis for IFOSFAMIDE.

Top Adverse Reactions

OFF LABEL USE2,694 reports
FEBRILE NEUTROPENIA2,624 reports
DISEASE PROGRESSION2,068 reports
NEUTROPENIA1,858 reports
DRUG INEFFECTIVE1,540 reports
THROMBOCYTOPENIA1,488 reports
ANAEMIA1,211 reports
PYREXIA967 reports
PRODUCT USE IN UNAPPROVED INDICATION934 reports
SEPSIS865 reports
INFECTION787 reports
PANCYTOPENIA746 reports
VOMITING731 reports
NAUSEA724 reports
MALIGNANT NEOPLASM PROGRESSION702 reports
MUCOSAL INFLAMMATION696 reports
DIARRHOEA623 reports
ENCEPHALOPATHY601 reports
DEATH569 reports
MYELODYSPLASTIC SYNDROME554 reports
CYTOPENIA535 reports
ACUTE MYELOID LEUKAEMIA508 reports
MYELOSUPPRESSION505 reports
LEUKOPENIA454 reports
PNEUMONIA448 reports
ACUTE KIDNEY INJURY431 reports
BONE MARROW FAILURE415 reports
TOXICITY TO VARIOUS AGENTS400 reports
ASPERGILLUS INFECTION385 reports
PLATELET COUNT DECREASED382 reports
ATRIAL FIBRILLATION368 reports
HAEMORRHAGE368 reports
NEOPLASM PROGRESSION348 reports
WHITE BLOOD CELL COUNT DECREASED346 reports
NEUROTOXICITY337 reports
SEPTIC SHOCK336 reports
HAEMATOTOXICITY333 reports
DISEASE RECURRENCE320 reports
DIFFUSE LARGE B CELL LYMPHOMA318 reports
PRODUCT USE ISSUE318 reports
FATIGUE312 reports
CYTOKINE RELEASE SYNDROME304 reports
DECREASED APPETITE281 reports
STOMATITIS279 reports
DYSPNOEA273 reports
DIFFUSE LARGE B CELL LYMPHOMA RECURRENT270 reports
RENAL FAILURE270 reports
RESPIRATORY FAILURE268 reports
NEUROPATHY PERIPHERAL267 reports
THERAPY PARTIAL RESPONDER263 reports
DRUG INTERACTION257 reports
ASTHENIA254 reports
RENAL IMPAIRMENT249 reports
THERAPY NON RESPONDER247 reports
CONFUSIONAL STATE243 reports
ABDOMINAL PAIN236 reports
HYPOTENSION234 reports
HAEMOGLOBIN DECREASED228 reports
SECOND PRIMARY MALIGNANCY228 reports
BLOOD LACTATE DEHYDROGENASE INCREASED224 reports
NEUTROPENIC SEPSIS217 reports
COVID 19215 reports
NEUTROPHIL COUNT DECREASED211 reports
TREATMENT FAILURE210 reports
HYPOKALAEMIA199 reports
PLEURAL EFFUSION198 reports
TUMOUR LYSIS SYNDROME194 reports
NEPHROPATHY TOXIC193 reports
WEIGHT DECREASED192 reports
PAIN190 reports
CONSTIPATION184 reports
DRUG INEFFECTIVE FOR UNAPPROVED INDICATION180 reports
BLOOD CREATININE INCREASED177 reports
CARDIOTOXICITY177 reports
CONDITION AGGRAVATED173 reports
HEADACHE171 reports
ALANINE AMINOTRANSFERASE INCREASED167 reports
TACHYCARDIA158 reports
MULTIPLE ORGAN DYSFUNCTION SYNDROME157 reports
DIFFUSE LARGE B CELL LYMPHOMA REFRACTORY155 reports
RASH149 reports
CHILLS148 reports
DEHYDRATION148 reports
CARDIAC FAILURE147 reports
SEIZURE138 reports
STAPHYLOCOCCAL INFECTION137 reports
METASTASES TO LUNG136 reports
LYMPHOMA132 reports
LYMPHADENOPATHY129 reports
ASCITES127 reports
DRUG RESISTANCE126 reports
FEBRILE BONE MARROW APLASIA125 reports
COLITIS123 reports
INTENTIONAL PRODUCT USE ISSUE123 reports
ALOPECIA122 reports
MALAISE122 reports
THERAPEUTIC PRODUCT EFFECT INCOMPLETE122 reports
HEPATOTOXICITY121 reports
CYTOMEGALOVIRUS INFECTION120 reports
MENINGITIS TUBERCULOUS119 reports

Report Outcomes

Out of 20,616 classified reports for IFOSFAMIDE:

Serious 97.5%Non-Serious 2.5%

The FDA classifies an adverse event as “serious” if it results in death, hospitalization, disability, congenital anomaly, or requires intervention to prevent permanent damage.

Demographics Breakdown

Reports by Sex

Male9,377 (57.6%)
Female6,730 (41.4%)
Unknown161 (1.0%)

Reports by Age

Age 16382 reports
Age 15347 reports
Age 14322 reports
Age 17316 reports
Age 12311 reports
Age 13270 reports
Age 18268 reports
Age 61258 reports
Age 67252 reports
Age 11245 reports
Age 64244 reports
Age 60239 reports
Age 20232 reports
Age 57231 reports
Age 62231 reports
Age 65228 reports
Age 58223 reports
Age 44222 reports
Age 9218 reports
Age 55217 reports

Demographics reflect voluntary FDA adverse event reporting patterns and may not represent the full patient population.

Frequently Asked Questions

How many FDA adverse event reports are associated with IFOSFAMIDE?

This profile reflects 42,356 FDA FAERS reports that mention IFOSFAMIDE. Reporting is voluntary and does not prove that the drug caused any listed event.

Which adverse reactions are most often listed for IFOSFAMIDE?

Frequently reported terms in FAERS include OFF LABEL USE, FEBRILE NEUTROPENIA, DISEASE PROGRESSION, NEUTROPENIA, DRUG INEFFECTIVE, THROMBOCYTOPENIA. Rankings reflect reporting volume in this dataset, not confirmed side effect rates in the general population.

Who manufactures IFOSFAMIDE?

Labeling and FAERS entries often list Baxter Healthcare Corporation in connection with IFOSFAMIDE. Always verify the specific product and NDC with your pharmacist.

Important Disclaimer: This content is generated by AI analysis of FDA adverse event reports and is provided for informational purposes only. It is not medical advice. Adverse event reports submitted to the FDA do not prove that a medication caused the reported side effect. Always consult your healthcare provider before starting, stopping, or changing any medication. If you experience a serious side effect, contact your doctor or call 911 immediately.