LEVODOPA

N/A

Manufactured by Merz Pharmaceuticals, LLC

26,727 FDA adverse event reports analyzed

Last updated: 2026-04-14

About LEVODOPA

LEVODOPA is a medication tracked in the FDA Adverse Event Reporting System (FAERS), manufactured by Merz Pharmaceuticals, LLC. The most commonly reported adverse reactions for LEVODOPA include COUGH, DRUG INEFFECTIVE, PARKINSON^S DISEASE, DYSKINESIA, DEATH. This page provides a comprehensive breakdown of reported side effects, safety signals, patient demographics, and AI-powered safety analysis for LEVODOPA.

Top Adverse Reactions

COUGH2,192 reports
DRUG INEFFECTIVE1,358 reports
PARKINSON^S DISEASE1,033 reports
DYSKINESIA732 reports
DEATH669 reports
FALL667 reports
CONDITION AGGRAVATED662 reports
DEVICE ISSUE655 reports
HALLUCINATION613 reports
PRODUCT RESIDUE PRESENT541 reports
TREMOR507 reports
DEVICE DIFFICULT TO USE488 reports
DEVICE USE ISSUE449 reports
DIZZINESS436 reports
FATIGUE426 reports
GAIT DISTURBANCE393 reports
NAUSEA393 reports
SOMNOLENCE379 reports
DYSPNOEA378 reports
THERAPEUTIC PRODUCT EFFECT VARIABLE321 reports
ON AND OFF PHENOMENON300 reports
OFF LABEL USE295 reports
CONFUSIONAL STATE288 reports
INSOMNIA269 reports
WRONG TECHNIQUE IN DEVICE USAGE PROCESS269 reports
MALAISE265 reports
DEVICE OCCLUSION263 reports
ANXIETY261 reports
FEELING ABNORMAL246 reports
ASTHENIA245 reports
CHOKING242 reports
INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION237 reports
HALLUCINATION, VISUAL228 reports
SPEECH DISORDER228 reports
WRONG TECHNIQUE IN PRODUCT USAGE PROCESS228 reports
CONSTIPATION225 reports
SPUTUM DISCOLOURED218 reports
PAIN215 reports
VOMITING208 reports
THROAT IRRITATION202 reports
BALANCE DISORDER201 reports
MUSCLE RIGIDITY201 reports
HEADACHE200 reports
PNEUMONIA200 reports
MEMORY IMPAIRMENT198 reports
INTENTIONAL UNDERDOSE197 reports
WEIGHT DECREASED194 reports
INCORRECT DOSE ADMINISTERED192 reports
URINARY TRACT INFECTION190 reports
GENERAL PHYSICAL HEALTH DETERIORATION189 reports
HYPOTENSION189 reports
FREEZING PHENOMENON188 reports
DRUG INTERACTION185 reports
MUSCULOSKELETAL STIFFNESS185 reports
THERAPEUTIC PRODUCT EFFECT INCOMPLETE184 reports
MOBILITY DECREASED173 reports
ILL DEFINED DISORDER167 reports
MUSCLE SPASMS165 reports
PRODUCT DOSE OMISSION ISSUE160 reports
INCORRECT DOSE ADMINISTERED BY DEVICE157 reports
ADVERSE EVENT156 reports
DEPRESSION150 reports
DYSPHAGIA149 reports
DYSTONIA148 reports
COGNITIVE DISORDER145 reports
BRADYKINESIA139 reports
DRY MOUTH138 reports
DECREASED APPETITE137 reports
AGITATION134 reports
DEMENTIA132 reports
DIARRHOEA132 reports
DELUSION127 reports
UNEVALUABLE EVENT127 reports
PAIN IN EXTREMITY126 reports
BLOOD PRESSURE DECREASED125 reports
SLEEP DISORDER125 reports
DELIRIUM124 reports
THERAPEUTIC PRODUCT EFFECT DECREASED124 reports
PRODUCT PHYSICAL ISSUE122 reports
RESTLESSNESS122 reports
HYPERHIDROSIS121 reports
BACK PAIN120 reports
SYNCOPE118 reports
MUSCULAR WEAKNESS117 reports
DEHYDRATION112 reports
THERAPY CESSATION111 reports
ARTHRALGIA109 reports
DRUG EFFECT LESS THAN EXPECTED108 reports
NEUROLEPTIC MALIGNANT SYNDROME106 reports
LOSS OF CONSCIOUSNESS105 reports
MOVEMENT DISORDER105 reports
PRESCRIBED UNDERDOSE101 reports
CHOKING SENSATION100 reports
PYREXIA100 reports
ABNORMAL BEHAVIOUR99 reports
ADVERSE DRUG REACTION97 reports
COVID 1997 reports
IMPULSE CONTROL DISORDER96 reports
ABDOMINAL PAIN92 reports
DEVICE DELIVERY SYSTEM ISSUE92 reports

Report Outcomes

Out of 11,483 classified reports for LEVODOPA:

Serious 49.2%Non-Serious 50.8%

The FDA classifies an adverse event as “serious” if it results in death, hospitalization, disability, congenital anomaly, or requires intervention to prevent permanent damage.

Demographics Breakdown

Reports by Sex

Male5,985 (56.4%)
Female4,619 (43.5%)
Unknown8 (0.1%)

Reports by Age

Age 78241 reports
Age 76228 reports
Age 74225 reports
Age 79225 reports
Age 70224 reports
Age 72223 reports
Age 75223 reports
Age 77222 reports
Age 73221 reports
Age 68220 reports
Age 71214 reports
Age 80208 reports
Age 69206 reports
Age 66167 reports
Age 67164 reports
Age 63159 reports
Age 65153 reports
Age 64150 reports
Age 81144 reports
Age 62126 reports

Demographics reflect voluntary FDA adverse event reporting patterns and may not represent the full patient population.

Frequently Asked Questions

How many FDA adverse event reports are associated with LEVODOPA?

This profile reflects 26,727 FDA FAERS reports that mention LEVODOPA. Reporting is voluntary and does not prove that the drug caused any listed event.

Which adverse reactions are most often listed for LEVODOPA?

Frequently reported terms in FAERS include COUGH, DRUG INEFFECTIVE, PARKINSON^S DISEASE, DYSKINESIA, DEATH, FALL. Rankings reflect reporting volume in this dataset, not confirmed side effect rates in the general population.

Who manufactures LEVODOPA?

Labeling and FAERS entries often list Merz Pharmaceuticals, LLC in connection with LEVODOPA. Always verify the specific product and NDC with your pharmacist.

Important Disclaimer: This content is generated by AI analysis of FDA adverse event reports and is provided for informational purposes only. It is not medical advice. Adverse event reports submitted to the FDA do not prove that a medication caused the reported side effect. Always consult your healthcare provider before starting, stopping, or changing any medication. If you experience a serious side effect, contact your doctor or call 911 immediately.