LIDOCAINE HCL

N/A

Manufactured by Chattem, Inc.

3,987 FDA adverse event reports analyzed

Last updated: 2026-04-15

About LIDOCAINE HCL

LIDOCAINE HCL is a medication tracked in the FDA Adverse Event Reporting System (FAERS), manufactured by Chattem, Inc.. The most commonly reported adverse reactions for LIDOCAINE HCL include DRUG HYPERSENSITIVITY, DRUG INEFFECTIVE, PAIN, TOXICITY TO VARIOUS AGENTS, NAUSEA. This page provides a comprehensive breakdown of reported side effects, safety signals, patient demographics, and AI-powered safety analysis for LIDOCAINE HCL.

Top Adverse Reactions

DRUG HYPERSENSITIVITY412 reports
DRUG INEFFECTIVE412 reports
PAIN127 reports
TOXICITY TO VARIOUS AGENTS90 reports
NAUSEA72 reports
DIZZINESS69 reports
FATIGUE69 reports
CARDIAC ARREST68 reports
DYSPNOEA62 reports
HYPOTENSION59 reports
RASH56 reports
HEADACHE55 reports
OFF LABEL USE55 reports
ARTHRALGIA53 reports
INJECTION SITE PAIN53 reports
DEATH49 reports
VOMITING47 reports
LOSS OF CONSCIOUSNESS46 reports
PYREXIA46 reports
HYPOAESTHESIA45 reports
PRODUCT USE ISSUE45 reports
OVERDOSE43 reports
HYPERTENSION42 reports
MUSCULAR WEAKNESS42 reports
PRODUCT QUALITY ISSUE42 reports
ANAPHYLACTIC REACTION41 reports
DIARRHOEA40 reports
CONDITION AGGRAVATED39 reports
DRUG INTERACTION39 reports
FEELING ABNORMAL39 reports
LAGOPHTHALMOS38 reports
PRURITUS38 reports
SEIZURE38 reports
MALAISE35 reports
HYPERSENSITIVITY34 reports
PAIN IN EXTREMITY33 reports
RESPIRATORY ARREST33 reports
NO ADVERSE EVENT32 reports
PNEUMONIA31 reports
FALL30 reports
SOMNOLENCE30 reports
ANXIETY29 reports
PRODUCT USE IN UNAPPROVED INDICATION29 reports
TREMOR29 reports
ARTHRITIS INFECTIVE28 reports
BURNING SENSATION28 reports
SWELLING28 reports
WEIGHT DECREASED28 reports
ERYTHEMA27 reports
PARAESTHESIA27 reports
URTICARIA27 reports
BLOOD PRESSURE INCREASED26 reports
BRADYCARDIA26 reports
INSOMNIA26 reports
STAPHYLOCOCCAL INFECTION26 reports
ANAESTHETIC COMPLICATION25 reports
BACK PAIN25 reports
TACHYCARDIA25 reports
ASTHENIA24 reports
GENERALISED TONIC CLONIC SEIZURE24 reports
NEUROTOXICITY24 reports
PALPITATIONS24 reports
SEPSIS24 reports
INFECTION23 reports
MYOPATHY TOXIC23 reports
CONSTIPATION22 reports
MUSCLE SPASMS22 reports
UNRESPONSIVE TO STIMULI22 reports
CONVULSION21 reports
DECREASED APPETITE21 reports
DEPRESSION21 reports
NEUROPATHY PERIPHERAL21 reports
VENTRICULAR TACHYCARDIA21 reports
SURGERY20 reports
AGITATION19 reports
CONFUSIONAL STATE19 reports
JOINT SWELLING19 reports
SYNCOPE19 reports
WEIGHT INCREASED19 reports
ANAEMIA18 reports
DYSARTHRIA18 reports
GAIT DISTURBANCE18 reports
METHAEMOGLOBINAEMIA18 reports
WRONG TECHNIQUE IN PRODUCT USAGE PROCESS18 reports
CELLULITIS17 reports
DEHYDRATION17 reports
DRUG ABUSE17 reports
HEART RATE INCREASED17 reports
PERIPHERAL SWELLING17 reports
ABDOMINAL DISCOMFORT16 reports
ATRIAL FIBRILLATION16 reports
CHEST PAIN16 reports
COUGH16 reports
DRUG EFFECT DECREASED16 reports
RENAL FAILURE16 reports
SINUS TACHYCARDIA16 reports
ARTHROPATHY15 reports
HYPERHIDROSIS15 reports
NASOPHARYNGITIS15 reports
POOR QUALITY DRUG ADMINISTERED15 reports

Report Outcomes

Out of 2,568 classified reports for LIDOCAINE HCL:

Serious 53.9%Non-Serious 46.1%

The FDA classifies an adverse event as “serious” if it results in death, hospitalization, disability, congenital anomaly, or requires intervention to prevent permanent damage.

Demographics Breakdown

Reports by Sex

Female1,395 (66.7%)
Male687 (32.8%)
Unknown10 (0.5%)

Reports by Age

Age 6545 reports
Age 5839 reports
Age 5939 reports
Age 6738 reports
Age 6337 reports
Age 6837 reports
Age 5534 reports
Age 7234 reports
Age 6932 reports
Age 6431 reports
Age 5230 reports
Age 7130 reports
Age 7829 reports
Age 5428 reports
Age 5628 reports
Age 6228 reports
Age 7428 reports
Age 7628 reports
Age 7928 reports
Age 5127 reports

Demographics reflect voluntary FDA adverse event reporting patterns and may not represent the full patient population.

Frequently Asked Questions

How many FDA adverse event reports are associated with LIDOCAINE HCL?

This profile reflects 3,987 FDA FAERS reports that mention LIDOCAINE HCL. Reporting is voluntary and does not prove that the drug caused any listed event.

Which adverse reactions are most often listed for LIDOCAINE HCL?

Frequently reported terms in FAERS include DRUG HYPERSENSITIVITY, DRUG INEFFECTIVE, PAIN, TOXICITY TO VARIOUS AGENTS, NAUSEA, DIZZINESS. Rankings reflect reporting volume in this dataset, not confirmed side effect rates in the general population.

Who manufactures LIDOCAINE HCL?

Labeling and FAERS entries often list Chattem, Inc. in connection with LIDOCAINE HCL. Always verify the specific product and NDC with your pharmacist.

Important Disclaimer: This content is generated by AI analysis of FDA adverse event reports and is provided for informational purposes only. It is not medical advice. Adverse event reports submitted to the FDA do not prove that a medication caused the reported side effect. Always consult your healthcare provider before starting, stopping, or changing any medication. If you experience a serious side effect, contact your doctor or call 911 immediately.