LIOTHYRONINE SODIUM

N/A

Manufactured by Pfizer Laboratories Div Pfizer Inc

23,445 FDA adverse event reports analyzed

Last updated: 2026-04-14

About LIOTHYRONINE SODIUM

LIOTHYRONINE SODIUM is a medication tracked in the FDA Adverse Event Reporting System (FAERS), manufactured by Pfizer Laboratories Div Pfizer Inc. The most commonly reported adverse reactions for LIOTHYRONINE SODIUM include DRUG INEFFECTIVE, HEADACHE, FATIGUE, NAUSEA, DYSPNOEA. This page provides a comprehensive breakdown of reported side effects, safety signals, patient demographics, and AI-powered safety analysis for LIOTHYRONINE SODIUM.

Top Adverse Reactions

DRUG INEFFECTIVE936 reports
HEADACHE859 reports
FATIGUE815 reports
NAUSEA569 reports
DYSPNOEA549 reports
PAIN469 reports
HYPERTENSION461 reports
MALAISE431 reports
WEIGHT INCREASED431 reports
HYPOTHYROIDISM426 reports
FEELING ABNORMAL410 reports
DIZZINESS385 reports
DIARRHOEA374 reports
OFF LABEL USE361 reports
ASTHMA354 reports
INSOMNIA351 reports
GASTROOESOPHAGEAL REFLUX DISEASE350 reports
BURNING SENSATION332 reports
ANXIETY329 reports
FIBROMYALGIA327 reports
ASTHENIA323 reports
CARDIAC DISORDER323 reports
THERAPEUTIC PRODUCT EFFECT INCOMPLETE319 reports
ARTHRALGIA316 reports
DEPRESSION314 reports
SLEEP APNOEA SYNDROME312 reports
ALOPECIA304 reports
CARPAL TUNNEL SYNDROME285 reports
WEIGHT DECREASED285 reports
BLOOD TEST ABNORMAL274 reports
RHINITIS ALLERGIC264 reports
POLYCYSTIC OVARIES263 reports
SENSITISATION260 reports
PALPITATIONS259 reports
RENAL DISORDER257 reports
LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES252 reports
SLEEP DISORDER DUE TO A GENERAL MEDICAL CONDITION252 reports
VOMITING242 reports
WHEEZING235 reports
RASH225 reports
PRURITUS221 reports
PAIN IN EXTREMITY220 reports
FALL214 reports
CONDITION AGGRAVATED212 reports
EJECTION FRACTION211 reports
TREMOR194 reports
DRUG HYPERSENSITIVITY190 reports
CONSTIPATION189 reports
SOMNOLENCE188 reports
MUSCLE SPASMS187 reports
COUGH186 reports
BACK PAIN178 reports
MYALGIA172 reports
PRODUCT DOSE OMISSION ISSUE172 reports
HYPERSENSITIVITY170 reports
SINUSITIS165 reports
CHEST PAIN161 reports
PARAESTHESIA160 reports
URTICARIA159 reports
MIGRAINE156 reports
ABDOMINAL DISTENSION155 reports
ABDOMINAL PAIN UPPER154 reports
HEART RATE INCREASED152 reports
GAIT DISTURBANCE147 reports
BLOOD PRESSURE INCREASED146 reports
HYPERHIDROSIS145 reports
PYREXIA144 reports
ABDOMINAL DISCOMFORT136 reports
HOSPITALISATION136 reports
URINARY TRACT INFECTION136 reports
COVID 19134 reports
INJECTION SITE PAIN132 reports
ABDOMINAL PAIN127 reports
ILLNESS127 reports
NASOPHARYNGITIS123 reports
HYPOAESTHESIA122 reports
PERIPHERAL SWELLING122 reports
VISION BLURRED122 reports
DECREASED APPETITE121 reports
CHEST DISCOMFORT113 reports
INTENTIONAL PRODUCT USE ISSUE112 reports
PRODUCT QUALITY ISSUE112 reports
SUICIDAL IDEATION110 reports
INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION109 reports
PRODUCT SUBSTITUTION ISSUE106 reports
MUSCULAR WEAKNESS105 reports
OEDEMA PERIPHERAL103 reports
CONFUSIONAL STATE99 reports
ERYTHEMA99 reports
MEMORY IMPAIRMENT98 reports
PNEUMONIA98 reports
DRY MOUTH97 reports
DYSPEPSIA96 reports
ADVERSE EVENT93 reports
DEATH92 reports
WRONG TECHNIQUE IN PRODUCT USAGE PROCESS89 reports
INCORRECT DOSE ADMINISTERED88 reports
BLOOD GLUCOSE INCREASED86 reports
THERAPEUTIC RESPONSE UNEXPECTED86 reports
FLUSHING85 reports

Report Outcomes

Out of 8,403 classified reports for LIOTHYRONINE SODIUM:

Serious 45.6%Non-Serious 54.4%

The FDA classifies an adverse event as “serious” if it results in death, hospitalization, disability, congenital anomaly, or requires intervention to prevent permanent damage.

Demographics Breakdown

Reports by Sex

Female6,867 (88.9%)
Male850 (11.0%)
Unknown7 (0.1%)

Reports by Age

Age 54375 reports
Age 62145 reports
Age 64144 reports
Age 56130 reports
Age 59129 reports
Age 55127 reports
Age 60125 reports
Age 61125 reports
Age 63125 reports
Age 53122 reports
Age 57120 reports
Age 51117 reports
Age 65117 reports
Age 45108 reports
Age 52108 reports
Age 66103 reports
Age 58102 reports
Age 4998 reports
Age 4797 reports
Age 5094 reports

Demographics reflect voluntary FDA adverse event reporting patterns and may not represent the full patient population.

Frequently Asked Questions

How many FDA adverse event reports are associated with LIOTHYRONINE SODIUM?

This profile reflects 23,445 FDA FAERS reports that mention LIOTHYRONINE SODIUM. Reporting is voluntary and does not prove that the drug caused any listed event.

Which adverse reactions are most often listed for LIOTHYRONINE SODIUM?

Frequently reported terms in FAERS include DRUG INEFFECTIVE, HEADACHE, FATIGUE, NAUSEA, DYSPNOEA, PAIN. Rankings reflect reporting volume in this dataset, not confirmed side effect rates in the general population.

Who manufactures LIOTHYRONINE SODIUM?

Labeling and FAERS entries often list Pfizer Laboratories Div Pfizer Inc in connection with LIOTHYRONINE SODIUM. Always verify the specific product and NDC with your pharmacist.

Important Disclaimer: This content is generated by AI analysis of FDA adverse event reports and is provided for informational purposes only. It is not medical advice. Adverse event reports submitted to the FDA do not prove that a medication caused the reported side effect. Always consult your healthcare provider before starting, stopping, or changing any medication. If you experience a serious side effect, contact your doctor or call 911 immediately.