LOPINAVIR AND RITONAVIR

N/A

Manufactured by AbbVie Inc.

28,252 FDA adverse event reports analyzed

Last updated: 2026-04-14

About LOPINAVIR AND RITONAVIR

LOPINAVIR AND RITONAVIR is a medication tracked in the FDA Adverse Event Reporting System (FAERS), manufactured by AbbVie Inc.. The most commonly reported adverse reactions for LOPINAVIR AND RITONAVIR include DRUG INTERACTION, DEPRESSION, DRUG EXPOSURE DURING PREGNANCY, DIARRHOEA, NAUSEA. This page provides a comprehensive breakdown of reported side effects, safety signals, patient demographics, and AI-powered safety analysis for LOPINAVIR AND RITONAVIR.

Top Adverse Reactions

DRUG INTERACTION1,324 reports
DEPRESSION1,125 reports
DRUG EXPOSURE DURING PREGNANCY781 reports
DIARRHOEA774 reports
NAUSEA765 reports
FOETAL EXPOSURE DURING PREGNANCY750 reports
ANXIETY711 reports
PAIN692 reports
VOMITING685 reports
OFF LABEL USE664 reports
EMOTIONAL DISTRESS576 reports
RENAL FAILURE540 reports
PYREXIA523 reports
ANHEDONIA508 reports
ANAEMIA449 reports
CHRONIC KIDNEY DISEASE430 reports
ABORTION SPONTANEOUS420 reports
PNEUMONIA401 reports
OSTEOPOROSIS399 reports
LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES342 reports
PREMATURE BABY341 reports
FATIGUE336 reports
BONE DENSITY DECREASED334 reports
ASTHENIA331 reports
MATERNAL EXPOSURE DURING PREGNANCY305 reports
EXPOSURE DURING PREGNANCY299 reports
PSYCHOTIC DISORDER296 reports
RENAL FAILURE ACUTE293 reports
LIPODYSTROPHY ACQUIRED291 reports
CONDITION AGGRAVATED290 reports
BLOOD BILIRUBIN INCREASED285 reports
WEIGHT DECREASED281 reports
ACUTE KIDNEY INJURY278 reports
ABDOMINAL PAIN275 reports
RENAL IMPAIRMENT268 reports
HEADACHE260 reports
DEATH251 reports
OSTEONECROSIS250 reports
ALANINE AMINOTRANSFERASE INCREASED241 reports
BLOOD CREATININE INCREASED241 reports
ASPARTATE AMINOTRANSFERASE INCREASED238 reports
CHOLELITHIASIS235 reports
DYSPNOEA234 reports
HEPATOTOXICITY234 reports
HEPATIC ENZYME INCREASED227 reports
OSTEOPENIA214 reports
RASH214 reports
ECONOMIC PROBLEM211 reports
SCHIZOPHRENIA206 reports
MALAISE203 reports
DIZZINESS202 reports
STILLBIRTH202 reports
DRUG INEFFECTIVE197 reports
GENERAL PHYSICAL HEALTH DETERIORATION196 reports
ABORTION INDUCED192 reports
MITOCHONDRIAL TOXICITY177 reports
ARTHRALGIA176 reports
EYELID PTOSIS176 reports
DIPLOPIA175 reports
PANCYTOPENIA172 reports
OEDEMA PERIPHERAL171 reports
RENAL INJURY170 reports
PRODUCT USE IN UNAPPROVED INDICATION168 reports
SUICIDAL IDEATION167 reports
BONE LOSS165 reports
DYSPHAGIA160 reports
JAUNDICE CHOLESTATIC159 reports
MULTIPLE FRACTURES159 reports
HYPOMANIA156 reports
THROMBOCYTOPENIA156 reports
HYPERTENSION154 reports
MYALGIA152 reports
INSOMNIA147 reports
HYPERTRIGLYCERIDAEMIA146 reports
DEHYDRATION140 reports
NEUTROPENIA140 reports
CARDIAC MURMUR139 reports
IMMUNE RECONSTITUTION SYNDROME137 reports
PRURITUS136 reports
DECREASED APPETITE134 reports
SKELETAL INJURY134 reports
CAESAREAN SECTION133 reports
PREGNANCY133 reports
BACK PAIN132 reports
PAIN IN EXTREMITY130 reports
SEPSIS129 reports
MYOCARDIAL INFARCTION128 reports
BLOOD ALKALINE PHOSPHATASE INCREASED127 reports
GAIT DISTURBANCE126 reports
DRUG RESISTANCE125 reports
LIVER DISORDER125 reports
PARANOIA123 reports
TEARFULNESS123 reports
METABOLIC ACIDOSIS122 reports
FANCONI SYNDROME ACQUIRED121 reports
PSYCHIATRIC DECOMPENSATION121 reports
ABDOMINAL DISTENSION120 reports
BLOOD TRIGLYCERIDES INCREASED120 reports
GASTROINTESTINAL DISORDER119 reports
LACTIC ACIDOSIS119 reports

Report Outcomes

Out of 13,413 classified reports for LOPINAVIR AND RITONAVIR:

Serious 92.0%Non-Serious 8.0%

The FDA classifies an adverse event as “serious” if it results in death, hospitalization, disability, congenital anomaly, or requires intervention to prevent permanent damage.

Demographics Breakdown

Reports by Sex

Male7,685 (62.9%)
Female4,466 (36.5%)
Unknown72 (0.6%)

Reports by Age

Age 54773 reports
Age 52438 reports
Age 36214 reports
Age 40208 reports
Age 44202 reports
Age 41195 reports
Age 39193 reports
Age 35188 reports
Age 34186 reports
Age 43185 reports
Age 49184 reports
Age 37181 reports
Age 50164 reports
Age 48163 reports
Age 45162 reports
Age 33157 reports
Age 42148 reports
Age 38144 reports
Age 53142 reports
Age 56141 reports

Demographics reflect voluntary FDA adverse event reporting patterns and may not represent the full patient population.

Frequently Asked Questions

How many FDA adverse event reports are associated with LOPINAVIR AND RITONAVIR?

This profile reflects 28,252 FDA FAERS reports that mention LOPINAVIR AND RITONAVIR. Reporting is voluntary and does not prove that the drug caused any listed event.

Which adverse reactions are most often listed for LOPINAVIR AND RITONAVIR?

Frequently reported terms in FAERS include DRUG INTERACTION, DEPRESSION, DRUG EXPOSURE DURING PREGNANCY, DIARRHOEA, NAUSEA, FOETAL EXPOSURE DURING PREGNANCY. Rankings reflect reporting volume in this dataset, not confirmed side effect rates in the general population.

Who manufactures LOPINAVIR AND RITONAVIR?

Labeling and FAERS entries often list AbbVie Inc. in connection with LOPINAVIR AND RITONAVIR. Always verify the specific product and NDC with your pharmacist.

Important Disclaimer: This content is generated by AI analysis of FDA adverse event reports and is provided for informational purposes only. It is not medical advice. Adverse event reports submitted to the FDA do not prove that a medication caused the reported side effect. Always consult your healthcare provider before starting, stopping, or changing any medication. If you experience a serious side effect, contact your doctor or call 911 immediately.