MERCAPTOPURINE

N/A

Manufactured by Florida Pharmaceutical Products, LLC

30,320 FDA adverse event reports analyzed

Last updated: 2026-04-14

About MERCAPTOPURINE

MERCAPTOPURINE is a medication tracked in the FDA Adverse Event Reporting System (FAERS), manufactured by Florida Pharmaceutical Products, LLC. The most commonly reported adverse reactions for MERCAPTOPURINE include FEBRILE NEUTROPENIA, PYREXIA, OFF LABEL USE, DRUG INEFFECTIVE, NAUSEA. This page provides a comprehensive breakdown of reported side effects, safety signals, patient demographics, and AI-powered safety analysis for MERCAPTOPURINE.

Top Adverse Reactions

FEBRILE NEUTROPENIA1,857 reports
PYREXIA1,177 reports
OFF LABEL USE1,102 reports
DRUG INEFFECTIVE1,082 reports
NAUSEA779 reports
VOMITING739 reports
DIARRHOEA685 reports
ABDOMINAL PAIN678 reports
HEADACHE588 reports
NEUTROPENIA584 reports
FATIGUE544 reports
PNEUMONIA507 reports
CROHN^S DISEASE502 reports
SEPSIS487 reports
ANAEMIA457 reports
CONDITION AGGRAVATED438 reports
PANCYTOPENIA407 reports
BACTERIAL INFECTION371 reports
ARTHRALGIA366 reports
COUGH363 reports
DYSPNOEA329 reports
MYELOSUPPRESSION327 reports
COLITIS ULCERATIVE316 reports
THROMBOCYTOPENIA316 reports
INJECTION SITE PAIN309 reports
RASH302 reports
VIRAL INFECTION300 reports
MALAISE297 reports
PAIN291 reports
DEATH289 reports
ASTHENIA280 reports
HYPOTENSION280 reports
PANCREATITIS279 reports
PLATELET COUNT DECREASED277 reports
CLOSTRIDIUM DIFFICILE COLITIS262 reports
WEIGHT DECREASED262 reports
ALANINE AMINOTRANSFERASE INCREASED260 reports
INFECTION248 reports
DRUG INTERACTION238 reports
BACK PAIN236 reports
SECONDARY IMMUNODEFICIENCY236 reports
CROHN'S DISEASE233 reports
COLITIS232 reports
DIZZINESS231 reports
WHITE BLOOD CELL COUNT DECREASED230 reports
HEPATOTOXICITY227 reports
PRODUCT USE IN UNAPPROVED INDICATION225 reports
DECREASED APPETITE221 reports
TACHYCARDIA218 reports
PAIN IN EXTREMITY216 reports
CHILLS214 reports
HAEMOGLOBIN DECREASED205 reports
CELLULITIS203 reports
NEUTROPHIL COUNT DECREASED203 reports
MUCOSAL INFLAMMATION198 reports
WEIGHT INCREASED198 reports
RESPIRATORY FAILURE197 reports
RHINOVIRUS INFECTION196 reports
SEPTIC SHOCK194 reports
INCORRECT DOSE ADMINISTERED190 reports
ACUTE KIDNEY INJURY188 reports
OSTEONECROSIS188 reports
FUNGAL INFECTION186 reports
SEIZURE185 reports
VENOOCCLUSIVE LIVER DISEASE185 reports
BRONCHOPULMONARY ASPERGILLOSIS184 reports
TOXICITY TO VARIOUS AGENTS183 reports
LEUKOPENIA179 reports
ABDOMINAL PAIN UPPER178 reports
NEUROPATHY PERIPHERAL178 reports
HYPERTENSION177 reports
STOMATITIS176 reports
DEHYDRATION175 reports
NEUROTOXICITY175 reports
CONSTIPATION172 reports
ENTERITIS172 reports
BONE MARROW FAILURE169 reports
COVID 19168 reports
PANCREATITIS ACUTE167 reports
PARAINFLUENZAE VIRUS INFECTION167 reports
PSEUDOMONAL SEPSIS167 reports
ACUTE MYELOID LEUKAEMIA164 reports
DRUG INTOLERANCE164 reports
ASPARTATE AMINOTRANSFERASE INCREASED163 reports
HUMAN HERPESVIRUS 6 INFECTION163 reports
HAEMATOTOXICITY162 reports
MUSCULAR WEAKNESS161 reports
MYCOBACTERIUM CHELONAE INFECTION160 reports
BLOOD BILIRUBIN INCREASED158 reports
OROPHARYNGEAL PAIN158 reports
ASPERGILLUS INFECTION157 reports
INTENTIONAL PRODUCT USE ISSUE154 reports
INFUSION RELATED REACTION150 reports
CHEST PAIN147 reports
INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION147 reports
RHINORRHOEA147 reports
HYPERSENSITIVITY144 reports
PNEUMATOSIS INTESTINALIS142 reports
PRODUCT USE ISSUE141 reports
PRURITUS141 reports

Report Outcomes

Out of 16,849 classified reports for MERCAPTOPURINE:

Serious 86.2%Non-Serious 13.8%

The FDA classifies an adverse event as “serious” if it results in death, hospitalization, disability, congenital anomaly, or requires intervention to prevent permanent damage.

Demographics Breakdown

Reports by Sex

Male7,455 (51.4%)
Female6,944 (47.9%)
Unknown92 (0.6%)

Reports by Age

Age 4457 reports
Age 5436 reports
Age 3423 reports
Age 7346 reports
Age 16345 reports
Age 17343 reports
Age 18313 reports
Age 15311 reports
Age 13298 reports
Age 12275 reports
Age 9272 reports
Age 6270 reports
Age 11269 reports
Age 14267 reports
Age 10260 reports
Age 8224 reports
Age 2223 reports
Age 19216 reports
Age 31201 reports
Age 20183 reports

Demographics reflect voluntary FDA adverse event reporting patterns and may not represent the full patient population.

Frequently Asked Questions

How many FDA adverse event reports are associated with MERCAPTOPURINE?

This profile reflects 30,320 FDA FAERS reports that mention MERCAPTOPURINE. Reporting is voluntary and does not prove that the drug caused any listed event.

Which adverse reactions are most often listed for MERCAPTOPURINE?

Frequently reported terms in FAERS include FEBRILE NEUTROPENIA, PYREXIA, OFF LABEL USE, DRUG INEFFECTIVE, NAUSEA, VOMITING. Rankings reflect reporting volume in this dataset, not confirmed side effect rates in the general population.

Who manufactures MERCAPTOPURINE?

Labeling and FAERS entries often list Florida Pharmaceutical Products, LLC in connection with MERCAPTOPURINE. Always verify the specific product and NDC with your pharmacist.

Important Disclaimer: This content is generated by AI analysis of FDA adverse event reports and is provided for informational purposes only. It is not medical advice. Adverse event reports submitted to the FDA do not prove that a medication caused the reported side effect. Always consult your healthcare provider before starting, stopping, or changing any medication. If you experience a serious side effect, contact your doctor or call 911 immediately.