MINOCYCLINE HYDROCHLORIDE

N/A

Manufactured by Melinta Therapeutics, LLC

49,345 FDA adverse event reports analyzed

Last updated: 2026-04-15

About MINOCYCLINE HYDROCHLORIDE

MINOCYCLINE HYDROCHLORIDE is a medication tracked in the FDA Adverse Event Reporting System (FAERS), manufactured by Melinta Therapeutics, LLC. The most commonly reported adverse reactions for MINOCYCLINE HYDROCHLORIDE include DRUG INEFFECTIVE, OFF LABEL USE, DRUG INTOLERANCE, PAIN, RHEUMATOID ARTHRITIS. This page provides a comprehensive breakdown of reported side effects, safety signals, patient demographics, and AI-powered safety analysis for MINOCYCLINE HYDROCHLORIDE.

Top Adverse Reactions

DRUG INEFFECTIVE1,244 reports
OFF LABEL USE1,144 reports
DRUG INTOLERANCE926 reports
PAIN897 reports
RHEUMATOID ARTHRITIS884 reports
NAUSEA811 reports
DRUG HYPERSENSITIVITY777 reports
ARTHRALGIA772 reports
RASH750 reports
FATIGUE722 reports
JOINT SWELLING710 reports
CONDITION AGGRAVATED680 reports
PNEUMONIA668 reports
HEADACHE666 reports
GENERAL PHYSICAL HEALTH DETERIORATION640 reports
C REACTIVE PROTEIN INCREASED636 reports
SYSTEMIC LUPUS ERYTHEMATOSUS635 reports
MALAISE615 reports
ABDOMINAL DISCOMFORT613 reports
CONTRAINDICATED PRODUCT ADMINISTERED609 reports
WOUND593 reports
SYNOVITIS592 reports
PERICARDITIS591 reports
PEMPHIGUS588 reports
INFUSION RELATED REACTION583 reports
DIZZINESS577 reports
PRODUCT USE IN UNAPPROVED INDICATION571 reports
HEPATIC ENZYME INCREASED556 reports
TREATMENT FAILURE548 reports
ALOPECIA544 reports
OSTEOARTHRITIS542 reports
TYPE 2 DIABETES MELLITUS536 reports
INTENTIONAL PRODUCT USE ISSUE527 reports
DIARRHOEA523 reports
MOBILITY DECREASED522 reports
HYPERSENSITIVITY519 reports
SWELLING511 reports
GLOSSODYNIA500 reports
HYPOAESTHESIA499 reports
PSORIATIC ARTHROPATHY499 reports
PAIN IN EXTREMITY490 reports
THERAPEUTIC PRODUCT EFFECT DECREASED489 reports
MATERNAL EXPOSURE DURING PREGNANCY487 reports
STOMATITIS487 reports
SLEEP DISORDER486 reports
PRODUCT USE ISSUE485 reports
URTICARIA480 reports
VOMITING480 reports
ANTI CYCLIC CITRULLINATED PEPTIDE ANTIBODY POSITIVE479 reports
ARTHROPATHY476 reports
HAND DEFORMITY474 reports
MUSCULOSKELETAL STIFFNESS466 reports
HYPERTENSION465 reports
BLOOD CHOLESTEROL INCREASED464 reports
DYSPNOEA443 reports
DECREASED APPETITE440 reports
C REACTIVE PROTEIN ABNORMAL435 reports
DYSPEPSIA433 reports
THERAPEUTIC PRODUCT EFFECT INCOMPLETE431 reports
INSOMNIA420 reports
CONFUSIONAL STATE419 reports
RHEUMATIC FEVER413 reports
FIBROMYALGIA412 reports
HELICOBACTER INFECTION402 reports
DUODENAL ULCER PERFORATION398 reports
INJURY395 reports
FOLLICULITIS392 reports
ABDOMINAL DISTENSION375 reports
BLISTER374 reports
WEIGHT INCREASED373 reports
HYPERCHOLESTEROLAEMIA367 reports
RED BLOOD CELL SEDIMENTATION RATE INCREASED364 reports
DEPRESSION361 reports
ONYCHOMADESIS357 reports
EXPOSURE DURING PREGNANCY352 reports
DRUG INDUCED LIVER INJURY350 reports
ABDOMINAL PAIN UPPER348 reports
LIVER INJURY348 reports
PYREXIA348 reports
GAIT INABILITY346 reports
ILL DEFINED DISORDER343 reports
NASOPHARYNGITIS342 reports
ASTHENIA336 reports
INFLAMMATION331 reports
GASTROINTESTINAL DISORDER327 reports
DRY MOUTH322 reports
IMPAIRED HEALING313 reports
WHEEZING312 reports
IRRITABLE BOWEL SYNDROME311 reports
PERIPHERAL SWELLING310 reports
BURSITIS308 reports
MUSCULAR WEAKNESS300 reports
ONYCHOMYCOSIS300 reports
GASTROOESOPHAGEAL REFLUX DISEASE299 reports
PARAESTHESIA297 reports
GRIP STRENGTH DECREASED296 reports
MIGRAINE296 reports
INFECTION293 reports
OSTEOPOROSIS293 reports
NECK PAIN292 reports

Report Outcomes

Out of 5,528 classified reports for MINOCYCLINE HYDROCHLORIDE:

Serious 81.5%Non-Serious 18.5%

The FDA classifies an adverse event as “serious” if it results in death, hospitalization, disability, congenital anomaly, or requires intervention to prevent permanent damage.

Demographics Breakdown

Reports by Sex

Female3,324 (68.2%)
Male1,461 (30.0%)
Unknown87 (1.8%)

Reports by Age

Age 40674 reports
Age 43213 reports
Age 59194 reports
Age 65130 reports
Age 44108 reports
Age 5787 reports
Age 4882 reports
Age 5581 reports
Age 5880 reports
Age 6875 reports
Age 7464 reports
Age 3457 reports
Age 6954 reports
Age 6053 reports
Age 6653 reports
Age 5451 reports
Age 1750 reports
Age 6149 reports
Age 6448 reports
Age 5347 reports

Demographics reflect voluntary FDA adverse event reporting patterns and may not represent the full patient population.

Frequently Asked Questions

How many FDA adverse event reports are associated with MINOCYCLINE HYDROCHLORIDE?

This profile reflects 49,345 FDA FAERS reports that mention MINOCYCLINE HYDROCHLORIDE. Reporting is voluntary and does not prove that the drug caused any listed event.

Which adverse reactions are most often listed for MINOCYCLINE HYDROCHLORIDE?

Frequently reported terms in FAERS include DRUG INEFFECTIVE, OFF LABEL USE, DRUG INTOLERANCE, PAIN, RHEUMATOID ARTHRITIS, NAUSEA. Rankings reflect reporting volume in this dataset, not confirmed side effect rates in the general population.

Who manufactures MINOCYCLINE HYDROCHLORIDE?

Labeling and FAERS entries often list Melinta Therapeutics, LLC in connection with MINOCYCLINE HYDROCHLORIDE. Always verify the specific product and NDC with your pharmacist.

Important Disclaimer: This content is generated by AI analysis of FDA adverse event reports and is provided for informational purposes only. It is not medical advice. Adverse event reports submitted to the FDA do not prove that a medication caused the reported side effect. Always consult your healthcare provider before starting, stopping, or changing any medication. If you experience a serious side effect, contact your doctor or call 911 immediately.