PERAMPANEL

N/A

Manufactured by Catalyst Pharmaceuticals, Inc.

14,467 FDA adverse event reports analyzed

Last updated: 2026-04-15

About PERAMPANEL

PERAMPANEL is a medication tracked in the FDA Adverse Event Reporting System (FAERS), manufactured by Catalyst Pharmaceuticals, Inc.. The most commonly reported adverse reactions for PERAMPANEL include SEIZURE, DRUG INEFFECTIVE, OFF LABEL USE, SOMNOLENCE, AGGRESSION. This page provides a comprehensive breakdown of reported side effects, safety signals, patient demographics, and AI-powered safety analysis for PERAMPANEL.

Top Adverse Reactions

SEIZURE1,098 reports
DRUG INEFFECTIVE1,044 reports
OFF LABEL USE728 reports
SOMNOLENCE491 reports
AGGRESSION485 reports
DIZZINESS384 reports
EPILEPSY332 reports
STATUS EPILEPTICUS324 reports
DRUG INTERACTION323 reports
MULTIPLE DRUG RESISTANCE313 reports
FATIGUE292 reports
IRRITABILITY239 reports
CONDITION AGGRAVATED226 reports
FALL220 reports
PRODUCT USE IN UNAPPROVED INDICATION217 reports
SUICIDE ATTEMPT204 reports
GAIT DISTURBANCE199 reports
SUICIDAL IDEATION195 reports
HEADACHE167 reports
GENERALISED TONIC CLONIC SEIZURE163 reports
AGITATION160 reports
INTENTIONAL OVERDOSE158 reports
VOMITING150 reports
PNEUMONIA149 reports
RASH142 reports
WEIGHT INCREASED142 reports
OVERDOSE139 reports
PSYCHOTIC DISORDER135 reports
ANGER134 reports
DECREASED APPETITE133 reports
DIARRHOEA132 reports
NAUSEA131 reports
PYREXIA129 reports
TOXICITY TO VARIOUS AGENTS129 reports
TREMOR129 reports
DEPRESSION126 reports
DRUG RESISTANCE123 reports
WEIGHT DECREASED120 reports
COGNITIVE DISORDER119 reports
MEMORY IMPAIRMENT119 reports
BALANCE DISORDER118 reports
PRODUCT USE ISSUE117 reports
ANXIETY116 reports
ABNORMAL BEHAVIOUR111 reports
PNEUMONIA ASPIRATION102 reports
DRUG INEFFECTIVE FOR UNAPPROVED INDICATION101 reports
HOSPITALISATION101 reports
INSOMNIA100 reports
DEATH97 reports
HALLUCINATION96 reports
DYSARTHRIA95 reports
PRODUCT DOSE OMISSION ISSUE95 reports
PARTIAL SEIZURES94 reports
ATAXIA93 reports
CONFUSIONAL STATE92 reports
ALTERED STATE OF CONSCIOUSNESS89 reports
LOSS OF CONSCIOUSNESS87 reports
TREATMENT FAILURE86 reports
DISTURBANCE IN ATTENTION81 reports
HYPONATRAEMIA80 reports
MATERNAL EXPOSURE DURING PREGNANCY80 reports
HYPOTENSION78 reports
PETIT MAL EPILEPSY77 reports
ASTHENIA76 reports
EXPOSURE DURING PREGNANCY72 reports
FOETAL EXPOSURE DURING PREGNANCY65 reports
THROMBOCYTOPENIA63 reports
RESPIRATORY FAILURE61 reports
URINARY TRACT INFECTION61 reports
DEPRESSED MOOD59 reports
DEPRESSED LEVEL OF CONSCIOUSNESS58 reports
CONSTIPATION56 reports
DRUG INTOLERANCE56 reports
GENERAL PHYSICAL HEALTH DETERIORATION56 reports
FEELING ABNORMAL55 reports
MOOD ALTERED55 reports
HYPERAMMONAEMIA53 reports
SPEECH DISORDER53 reports
BRADYCARDIA52 reports
MALAISE52 reports
COMA51 reports
DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS51 reports
SEDATION51 reports
ANTICONVULSANT DRUG LEVEL INCREASED50 reports
BEHAVIOUR DISORDER50 reports
RESTLESSNESS50 reports
HOMICIDAL IDEATION49 reports
PRESCRIBED UNDERDOSE49 reports
ENCEPHALOPATHY48 reports
HALLUCINATION, AUDITORY48 reports
THERAPEUTIC PRODUCT EFFECT INCOMPLETE46 reports
DELIRIUM45 reports
ABORTION SPONTANEOUS44 reports
ANAEMIA44 reports
DRUG HYPERSENSITIVITY44 reports
SEIZURE CLUSTER44 reports
DISORIENTATION43 reports
MENTAL DISORDER43 reports
THERAPY NON RESPONDER43 reports
AMNESIA42 reports

Frequently Asked Questions

How many FDA adverse event reports are associated with PERAMPANEL?

This profile reflects 14,467 FDA FAERS reports that mention PERAMPANEL. Reporting is voluntary and does not prove that the drug caused any listed event.

Which adverse reactions are most often listed for PERAMPANEL?

Frequently reported terms in FAERS include SEIZURE, DRUG INEFFECTIVE, OFF LABEL USE, SOMNOLENCE, AGGRESSION, DIZZINESS. Rankings reflect reporting volume in this dataset, not confirmed side effect rates in the general population.

Who manufactures PERAMPANEL?

Labeling and FAERS entries often list Catalyst Pharmaceuticals, Inc. in connection with PERAMPANEL. Always verify the specific product and NDC with your pharmacist.

Important Disclaimer: This content is generated by AI analysis of FDA adverse event reports and is provided for informational purposes only. It is not medical advice. Adverse event reports submitted to the FDA do not prove that a medication caused the reported side effect. Always consult your healthcare provider before starting, stopping, or changing any medication. If you experience a serious side effect, contact your doctor or call 911 immediately.