PIPERACILLIN SODIUM,TAZOBACTAM SODIUM and OFF LABEL USE

Overview

OFF LABEL USE is the #2 most commonly reported adverse reaction for PIPERACILLIN SODIUM,TAZOBACTAM SODIUM, manufactured by Fresenius Kabi USA, LLC. There are 2,486 FDA adverse event reports linking PIPERACILLIN SODIUM,TAZOBACTAM SODIUM to OFF LABEL USE. This represents approximately 5.5% of all 44,977 adverse event reports for this drug.

Patients taking PIPERACILLIN SODIUM,TAZOBACTAM SODIUM who experience off label use should discuss this symptom with their healthcare provider to determine whether it may be related to their medication and what alternatives may be available.

Reporting Frequency

OFF LABEL USE2,486 of 44,977 reports

OFF LABEL USE is moderately reported among PIPERACILLIN SODIUM,TAZOBACTAM SODIUM users, representing a notable but not dominant share of adverse events.

Other Side Effects of PIPERACILLIN SODIUM,TAZOBACTAM SODIUM

In addition to off label use, the following adverse reactions have been reported for PIPERACILLIN SODIUM,TAZOBACTAM SODIUM:

DRUG INEFFECTIVE — 2,726 reports
ACUTE KIDNEY INJURY — 1,855 reports
PYREXIA — 1,628 reports
DIARRHOEA — 1,045 reports
CONDITION AGGRAVATED — 1,012 reports
THROMBOCYTOPENIA — 955 reports
PNEUMONIA — 931 reports
NEUTROPENIA — 909 reports
DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS — 865 reports
FEBRILE NEUTROPENIA — 815 reports

Other Drugs Associated with OFF LABEL USE

The following drugs have also been linked to off label use in FDA adverse event reports:

0XYGEN ABACAVIR SULFATE ABATACEPT ABIRATERONE ACETATE ACALABRUTINIB ACETAMINOPHEN ACETAMINOPHEN 500MG ACETAMINOPHEN AND CODEINE ACETAMINOPHEN AND DIPHENHYDRAMINE HYDROCHLORIDE ACETAMINOPHEN AND IBUPROFEN ACETAMINOPHEN AND PHENYLEPHRINE HYDROCHLORIDE ACETAMINOPHEN, ASPIRIN, AND CAFFEINE ACETAMINOPHEN, ASPIRIN, CAFFEINE ACETAMINOPHEN, ASPIRIN (NSAID) AND CAFFEINE ACETAMINOPHEN, CAFFEINE ACETAMINOPHEN, CHLORPHENIRAMINE MALEATE, DEXTROMETHORPHAN HYDROBROMIDE, AND PHENYLEPHRINE HYDROCHLORIDE ACETAMINOPHEN, CHLORPHENIRAMINE MALEATE, PHENYLEPHRINE HCL ACETAMINOPHEN, DIPHENHYDRAMINE HYDROCHLORIDE ACETAMINOPHEN, GUAIFENESIN, AND PHENYLEPHRINE HYDROCHLORIDE ACETAMINOPHEN, IBUPROFEN

Does PIPERACILLIN SODIUM,TAZOBACTAM SODIUM cause OFF LABEL USE?

OFF LABEL USE has been reported as an adverse event in 2,486 FDA reports for PIPERACILLIN SODIUM,TAZOBACTAM SODIUM. This does not prove causation, but indicates an association observed in post-market surveillance data.

How common is OFF LABEL USE with PIPERACILLIN SODIUM,TAZOBACTAM SODIUM?

OFF LABEL USE accounts for approximately 5.5% of all adverse event reports for PIPERACILLIN SODIUM,TAZOBACTAM SODIUM, making it one of the most commonly reported side effect.

What should I do if I experience OFF LABEL USE while taking PIPERACILLIN SODIUM,TAZOBACTAM SODIUM?

If you experience off label use while taking PIPERACILLIN SODIUM,TAZOBACTAM SODIUM, contact your healthcare provider. They can evaluate whether the symptom is related to your medication and discuss potential adjustments to your treatment plan. Do not stop taking prescribed medication without consulting your doctor.