PROCHLORPERAZINE

N/A

Manufactured by Padagis US LLC

58,040 FDA adverse event reports analyzed

Last updated: 2026-04-14

About PROCHLORPERAZINE

PROCHLORPERAZINE is a medication tracked in the FDA Adverse Event Reporting System (FAERS), manufactured by Padagis US LLC. The most commonly reported adverse reactions for PROCHLORPERAZINE include NAUSEA, FATIGUE, DIARRHOEA, VOMITING, FEBRILE NEUTROPENIA. This page provides a comprehensive breakdown of reported side effects, safety signals, patient demographics, and AI-powered safety analysis for PROCHLORPERAZINE.

Top Adverse Reactions

NAUSEA3,262 reports
FATIGUE2,707 reports
DIARRHOEA2,322 reports
VOMITING1,843 reports
FEBRILE NEUTROPENIA1,831 reports
DEATH1,706 reports
OFF LABEL USE1,299 reports
ASTHENIA1,255 reports
PNEUMONIA1,149 reports
DYSPNOEA1,101 reports
PYREXIA1,022 reports
DECREASED APPETITE1,014 reports
PAIN1,010 reports
HEADACHE973 reports
DIZZINESS961 reports
CONSTIPATION922 reports
MALAISE842 reports
RASH826 reports
DRUG INEFFECTIVE790 reports
DISEASE PROGRESSION782 reports
WEIGHT DECREASED774 reports
DEHYDRATION760 reports
ABDOMINAL PAIN753 reports
ANXIETY695 reports
FALL693 reports
PLATELET COUNT DECREASED670 reports
COUGH654 reports
WHITE BLOOD CELL COUNT DECREASED642 reports
ANAEMIA637 reports
ALOPECIA599 reports
ARTHRALGIA587 reports
HYPOTENSION582 reports
BACK PAIN570 reports
CONFUSIONAL STATE565 reports
NEUTROPENIA544 reports
ACUTE KIDNEY INJURY533 reports
BLOOD PRESSURE INCREASED504 reports
SEPSIS454 reports
URINARY TRACT INFECTION439 reports
PRURITUS432 reports
NEUROPATHY PERIPHERAL430 reports
THROMBOCYTOPENIA430 reports
HAEMOGLOBIN DECREASED422 reports
PAIN IN EXTREMITY422 reports
INSOMNIA415 reports
MALIGNANT NEOPLASM PROGRESSION409 reports
HYPERTENSION407 reports
MUSCLE SPASMS396 reports
DYSPHAGIA383 reports
ABDOMINAL PAIN UPPER372 reports
CHEST PAIN364 reports
MUSCULAR WEAKNESS354 reports
PALPITATIONS352 reports
CEREBROVASCULAR ACCIDENT344 reports
TREMOR339 reports
NASOPHARYNGITIS338 reports
PERIPHERAL SWELLING336 reports
SOMNOLENCE331 reports
INFECTION324 reports
HYPONATRAEMIA323 reports
PLEURAL EFFUSION323 reports
PRODUCT DOSE OMISSION ISSUE320 reports
ABDOMINAL DISCOMFORT316 reports
INFLUENZA315 reports
SINUSITIS307 reports
DEPRESSION306 reports
CHEST DISCOMFORT305 reports
PLASMA CELL MYELOMA304 reports
ATRIAL FIBRILLATION303 reports
RENAL FAILURE302 reports
PANCYTOPENIA298 reports
DYSPEPSIA283 reports
OEDEMA PERIPHERAL280 reports
MYALGIA279 reports
GASTROINTESTINAL DISORDER278 reports
PULMONARY EMBOLISM273 reports
HYPOAESTHESIA272 reports
SKIN EXFOLIATION270 reports
HOSPITALISATION269 reports
COVID 19264 reports
PARAESTHESIA264 reports
THROMBOSIS263 reports
DRUG HYPERSENSITIVITY261 reports
STOMATITIS261 reports
FEELING ABNORMAL258 reports
ARTHRITIS254 reports
CONDITION AGGRAVATED254 reports
CATARACT253 reports
GAIT DISTURBANCE253 reports
CHILLS249 reports
INFLUENZA LIKE ILLNESS249 reports
DRUG INTERACTION248 reports
CYTOKINE RELEASE SYNDROME247 reports
SYNCOPE244 reports
PRODUCT USE IN UNAPPROVED INDICATION242 reports
NEUTROPHIL COUNT DECREASED241 reports
RHINORRHOEA239 reports
HYPERHIDROSIS235 reports
CHRONIC KIDNEY DISEASE233 reports
TACHYCARDIA230 reports

Report Outcomes

Out of 26,597 classified reports for PROCHLORPERAZINE:

Serious 76.6%Non-Serious 23.4%

The FDA classifies an adverse event as “serious” if it results in death, hospitalization, disability, congenital anomaly, or requires intervention to prevent permanent damage.

Demographics Breakdown

Reports by Sex

Female14,237 (58.1%)
Male10,234 (41.8%)
Unknown26 (0.1%)

Reports by Age

Age 65688 reports
Age 66680 reports
Age 67634 reports
Age 71579 reports
Age 70573 reports
Age 61563 reports
Age 64560 reports
Age 69556 reports
Age 72554 reports
Age 68542 reports
Age 74519 reports
Age 62515 reports
Age 76514 reports
Age 73508 reports
Age 60492 reports
Age 63491 reports
Age 59488 reports
Age 75446 reports
Age 58445 reports
Age 77421 reports

Demographics reflect voluntary FDA adverse event reporting patterns and may not represent the full patient population.

Frequently Asked Questions

How many FDA adverse event reports are associated with PROCHLORPERAZINE?

This profile reflects 58,040 FDA FAERS reports that mention PROCHLORPERAZINE. Reporting is voluntary and does not prove that the drug caused any listed event.

Which adverse reactions are most often listed for PROCHLORPERAZINE?

Frequently reported terms in FAERS include NAUSEA, FATIGUE, DIARRHOEA, VOMITING, FEBRILE NEUTROPENIA, DEATH. Rankings reflect reporting volume in this dataset, not confirmed side effect rates in the general population.

Who manufactures PROCHLORPERAZINE?

Labeling and FAERS entries often list Padagis US LLC in connection with PROCHLORPERAZINE. Always verify the specific product and NDC with your pharmacist.

Important Disclaimer: This content is generated by AI analysis of FDA adverse event reports and is provided for informational purposes only. It is not medical advice. Adverse event reports submitted to the FDA do not prove that a medication caused the reported side effect. Always consult your healthcare provider before starting, stopping, or changing any medication. If you experience a serious side effect, contact your doctor or call 911 immediately.