PYRAZINAMIDE and ACUTE HEPATIC FAILURE

Overview

ACUTE HEPATIC FAILURE is the #19 most commonly reported adverse reaction for PYRAZINAMIDE, manufactured by ANI Pharmaceuticals, Inc.. There are 234 FDA adverse event reports linking PYRAZINAMIDE to ACUTE HEPATIC FAILURE. This represents approximately 1.4% of all 17,268 adverse event reports for this drug.

Patients taking PYRAZINAMIDE who experience acute hepatic failure should discuss this symptom with their healthcare provider to determine whether it may be related to their medication and what alternatives may be available.

Reporting Frequency

ACUTE HEPATIC FAILURE is a less commonly reported adverse event for PYRAZINAMIDE, but still significant enough to appear in the safety profile.

Other Side Effects of PYRAZINAMIDE

In addition to acute hepatic failure, the following adverse reactions have been reported for PYRAZINAMIDE:

• DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS — 665 reports
• DRUG INDUCED LIVER INJURY — 639 reports
• PYREXIA — 590 reports
• DRUG INTERACTION — 564 reports
• PARADOXICAL DRUG REACTION — 503 reports
• OFF LABEL USE — 489 reports
• VOMITING — 472 reports
• DRUG INEFFECTIVE — 465 reports
• TUBERCULOSIS — 391 reports
• NAUSEA — 390 reports

Other Drugs Associated with ACUTE HEPATIC FAILURE

The following drugs have also been linked to acute hepatic failure in FDA adverse event reports:

Does PYRAZINAMIDE cause ACUTE HEPATIC FAILURE?

ACUTE HEPATIC FAILURE has been reported as an adverse event in 234 FDA reports for PYRAZINAMIDE. This does not prove causation, but indicates an association observed in post-market surveillance data.

How common is ACUTE HEPATIC FAILURE with PYRAZINAMIDE?

ACUTE HEPATIC FAILURE accounts for approximately 1.4% of all adverse event reports for PYRAZINAMIDE, making it a notable side effect.

What should I do if I experience ACUTE HEPATIC FAILURE while taking PYRAZINAMIDE?

If you experience acute hepatic failure while taking PYRAZINAMIDE, contact your healthcare provider. They can evaluate whether the symptom is related to your medication and discuss potential adjustments to your treatment plan. Do not stop taking prescribed medication without consulting your doctor.

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