SEVELAMER CARBONATE

N/A

Manufactured by Genzyme Corporation

19,097 FDA adverse event reports analyzed

Last updated: 2026-04-14

About SEVELAMER CARBONATE

SEVELAMER CARBONATE is a medication tracked in the FDA Adverse Event Reporting System (FAERS), manufactured by Genzyme Corporation. The most commonly reported adverse reactions for SEVELAMER CARBONATE include CONSTIPATION, DIARRHOEA, PRURITUS, NAUSEA, CHRONIC KIDNEY DISEASE. This page provides a comprehensive breakdown of reported side effects, safety signals, patient demographics, and AI-powered safety analysis for SEVELAMER CARBONATE.

Top Adverse Reactions

CONSTIPATION2,539 reports
DIARRHOEA1,017 reports
PRURITUS1,006 reports
NAUSEA810 reports
CHRONIC KIDNEY DISEASE676 reports
END STAGE RENAL DISEASE671 reports
RENAL FAILURE662 reports
DEATH623 reports
VOMITING524 reports
ACUTE KIDNEY INJURY508 reports
ABDOMINAL PAIN302 reports
NEPHROGENIC ANAEMIA297 reports
DYSPNOEA291 reports
FATIGUE260 reports
FLATULENCE251 reports
PNEUMONIA233 reports
OFF LABEL USE218 reports
PAIN211 reports
HOSPITALISATION198 reports
HYPOTENSION196 reports
ASTHENIA192 reports
RASH187 reports
DYSPEPSIA181 reports
HYPERPARATHYROIDISM SECONDARY181 reports
DIZZINESS171 reports
ANAEMIA169 reports
HYPERPHOSPHATAEMIA169 reports
MALAISE168 reports
RENAL INJURY167 reports
DRUG INEFFECTIVE150 reports
HAEMOGLOBIN DECREASED147 reports
FALL144 reports
ABDOMINAL DISCOMFORT138 reports
SEPSIS135 reports
PYREXIA134 reports
ANXIETY131 reports
DECREASED APPETITE130 reports
OVERDOSE129 reports
ABDOMINAL PAIN UPPER128 reports
HYPERTENSION124 reports
DIALYSIS123 reports
HEADACHE121 reports
DRUG DOSE OMISSION119 reports
CARDIAC ARREST115 reports
WEIGHT DECREASED106 reports
ARTHRALGIA98 reports
CHEST PAIN97 reports
PERITONITIS97 reports
DEPRESSION93 reports
HYPERKALAEMIA92 reports
DYSPHAGIA89 reports
CHRONIC KIDNEY DISEASE MINERAL AND BONE DISORDER86 reports
EMOTIONAL DISTRESS86 reports
GASTROINTESTINAL HAEMORRHAGE86 reports
RENAL IMPAIRMENT86 reports
PAIN IN EXTREMITY85 reports
COUGH83 reports
MYOCARDIAL INFARCTION82 reports
PERITONITIS BACTERIAL82 reports
PRODUCT USE ISSUE82 reports
TREATMENT NONCOMPLIANCE81 reports
DRUG INTERACTION80 reports
URINARY TRACT INFECTION80 reports
ANHEDONIA78 reports
BACK PAIN76 reports
INTESTINAL OBSTRUCTION76 reports
RESPIRATORY FAILURE76 reports
CEREBROVASCULAR ACCIDENT75 reports
CONFUSIONAL STATE73 reports
RENAL DISORDER73 reports
TUBULOINTERSTITIAL NEPHRITIS73 reports
FLUID OVERLOAD72 reports
CARDIAC FAILURE70 reports
REBOUND ACID HYPERSECRETION70 reports
INAPPROPRIATE SCHEDULE OF DRUG ADMINISTRATION68 reports
BLOOD PHOSPHORUS INCREASED67 reports
ABDOMINAL DISTENSION66 reports
GASTROINTESTINAL DISORDER66 reports
BLOOD CREATININE INCREASED65 reports
CONDITION AGGRAVATED65 reports
INFECTION65 reports
PLATELET COUNT DECREASED65 reports
SEIZURE65 reports
BLOOD POTASSIUM INCREASED64 reports
BLOOD PRESSURE INCREASED64 reports
ATRIAL FIBRILLATION63 reports
OEDEMA PERIPHERAL63 reports
MUSCLE SPASMS62 reports
GAIT DISTURBANCE60 reports
CARDIAC FAILURE CONGESTIVE58 reports
DRUG HYPERSENSITIVITY58 reports
FEELING ABNORMAL57 reports
HAEMATOCHEZIA57 reports
BLOOD PRESSURE DECREASED54 reports
GASTROOESOPHAGEAL REFLUX DISEASE54 reports
COLITIS53 reports
SEPTIC SHOCK53 reports
SOMNOLENCE53 reports
NO ADVERSE EVENT52 reports
THROMBOCYTOPENIA51 reports

Report Outcomes

Out of 11,271 classified reports for SEVELAMER CARBONATE:

Serious 48.7%Non-Serious 51.3%

The FDA classifies an adverse event as “serious” if it results in death, hospitalization, disability, congenital anomaly, or requires intervention to prevent permanent damage.

Demographics Breakdown

Reports by Sex

Male3,667 (48.0%)
Female3,361 (44.0%)
Unknown608 (8.0%)

Reports by Age

Age 66153 reports
Age 60152 reports
Age 65146 reports
Age 58137 reports
Age 64136 reports
Age 68132 reports
Age 57128 reports
Age 61128 reports
Age 63126 reports
Age 67122 reports
Age 69122 reports
Age 70117 reports
Age 59115 reports
Age 62115 reports
Age 71114 reports
Age 74112 reports
Age 72110 reports
Age 56108 reports
Age 73105 reports
Age 75102 reports

Demographics reflect voluntary FDA adverse event reporting patterns and may not represent the full patient population.

Frequently Asked Questions

How many FDA adverse event reports are associated with SEVELAMER CARBONATE?

This profile reflects 19,097 FDA FAERS reports that mention SEVELAMER CARBONATE. Reporting is voluntary and does not prove that the drug caused any listed event.

Which adverse reactions are most often listed for SEVELAMER CARBONATE?

Frequently reported terms in FAERS include CONSTIPATION, DIARRHOEA, PRURITUS, NAUSEA, CHRONIC KIDNEY DISEASE, END STAGE RENAL DISEASE. Rankings reflect reporting volume in this dataset, not confirmed side effect rates in the general population.

Who manufactures SEVELAMER CARBONATE?

Labeling and FAERS entries often list Genzyme Corporation in connection with SEVELAMER CARBONATE. Always verify the specific product and NDC with your pharmacist.

Important Disclaimer: This content is generated by AI analysis of FDA adverse event reports and is provided for informational purposes only. It is not medical advice. Adverse event reports submitted to the FDA do not prove that a medication caused the reported side effect. Always consult your healthcare provider before starting, stopping, or changing any medication. If you experience a serious side effect, contact your doctor or call 911 immediately.