SULFACETAMIDE SODIUM

65/100 · Elevated

Manufactured by Bausch Health US, LLC

Moderate Safety Concerns with Sulfacetamide Sodium

1,112 FDA adverse event reports analyzed

Last updated: 2026-05-12

About SULFACETAMIDE SODIUM

SULFACETAMIDE SODIUM is a medication tracked in the FDA Adverse Event Reporting System (FAERS), manufactured by Bausch Health US, LLC. Based on analysis of 1,112 FDA adverse event reports, SULFACETAMIDE SODIUM has a safety score of 65 out of 100. This moderate score indicates a notable volume of adverse event reports that patients and providers should be aware of. The most commonly reported adverse reactions for SULFACETAMIDE SODIUM include DRUG HYPERSENSITIVITY, DRUG INEFFECTIVE, DYSPNOEA, NAUSEA, HEADACHE. This page provides a comprehensive breakdown of reported side effects, safety signals, patient demographics, and AI-powered safety analysis for SULFACETAMIDE SODIUM.

AI Safety Analysis

Sulfacetamide Sodium has a safety concern score of 65 out of 100, placing it in the elevated concern category based on analysis of FDA adverse event data. The FDA has received approximately 1,112 adverse event reports for this medication, which is primarily manufactured by Bausch Health Us, Llc.

The most commonly reported adverse events include Drug Hypersensitivity, Drug Ineffective, Dyspnoea. Of classified reports, 44.8% were designated as serious by the FDA, meaning they involved hospitalization, disability, or other significant medical outcomes. Drug hypersensitivity reactions are the most common serious adverse events.

A wide range of reactions indicates potential for diverse side effects. Reports of serious adverse events (44.8%) are concerning. Off-label use is a significant reported issue.

Patients taking Sulfacetamide Sodium should monitor for the commonly reported side effects and contact their healthcare provider if they experience any unusual symptoms. Interactions and warnings include potential for drug hypersensitivity and off-label use, which may require careful monitoring. This analysis is based on voluntary FDA adverse event reports and should not replace professional medical advice.

Safety Score: 65/100

Sulfacetamide Sodium received a safety concern score of 65/100 (elevated concern). This is based on a 44.8% serious event ratio across 460 classified reports. The score accounts for 1,112 total adverse event reports and 100 distinct reaction types. This elevated score indicates a notable proportion of serious adverse events and warrants careful monitoring.

Top Adverse Reactions

DRUG HYPERSENSITIVITY61 reports
DRUG INEFFECTIVE43 reports
DYSPNOEA29 reports
NAUSEA29 reports
HEADACHE27 reports
OFF LABEL USE25 reports
WEIGHT DECREASED23 reports
FATIGUE21 reports
RASH21 reports
VOMITING19 reports
ASTHENIA17 reports
BLOOD PRESSURE INCREASED17 reports
PAIN17 reports
DIZZINESS16 reports
BACK PAIN15 reports
COUGH15 reports
DIARRHOEA15 reports
INSOMNIA15 reports
PNEUMONIA15 reports
ASTHMA14 reports
ERYTHEMA14 reports
HYPERTENSION14 reports
PAIN IN EXTREMITY14 reports
PRURITUS14 reports
URTICARIA14 reports
ANXIETY13 reports
CONDITION AGGRAVATED13 reports
DEPRESSION13 reports
ARTHRALGIA12 reports
CONSTIPATION12 reports
HYPOAESTHESIA12 reports
MALAISE12 reports
ABDOMINAL PAIN11 reports
ANAEMIA11 reports
CHRONIC KIDNEY DISEASE11 reports
FALL11 reports
PALPITATIONS11 reports
TREMOR11 reports
CHEST PAIN10 reports
HYPERSENSITIVITY10 reports
PYREXIA10 reports
SINUSITIS10 reports
URINARY TRACT INFECTION10 reports
ALOPECIA9 reports
COVID 199 reports
DYSPHAGIA9 reports
INJECTION SITE PAIN9 reports
PRODUCT DOSE OMISSION ISSUE9 reports
PSORIASIS9 reports
WRONG TECHNIQUE IN PRODUCT USAGE PROCESS9 reports
ACUTE KIDNEY INJURY8 reports
CELLULITIS8 reports
EYE IRRITATION8 reports
FORCED EXPIRATORY VOLUME DECREASED8 reports
MEDICATION ERROR8 reports
MUSCLE SPASMS8 reports
OEDEMA PERIPHERAL8 reports
OROPHARYNGEAL PAIN8 reports
SOMNOLENCE8 reports
ABDOMINAL DISCOMFORT7 reports
ANAPHYLACTIC REACTION7 reports
ATRIAL FIBRILLATION7 reports
CONJUNCTIVITIS7 reports
DECREASED APPETITE7 reports
DEHYDRATION7 reports
DYSPNOEA EXERTIONAL7 reports
EAR PAIN7 reports
EYE DISORDER7 reports
FEELING ABNORMAL7 reports
GASTROOESOPHAGEAL REFLUX DISEASE7 reports
INJURY7 reports
MEMORY IMPAIRMENT7 reports
RENAL FAILURE7 reports
UPPER RESPIRATORY TRACT INFECTION7 reports
VISION BLURRED7 reports
BLOOD IMMUNOGLOBULIN E INCREASED6 reports
BRONCHITIS6 reports
CONTUSION6 reports
EAR PRURITUS6 reports
FLUSHING6 reports
ILLNESS6 reports
MIGRAINE6 reports
PARAESTHESIA6 reports
PRODUCT USE IN UNAPPROVED INDICATION6 reports
SKIN EXFOLIATION6 reports
SNEEZING6 reports
SURGERY6 reports
THERAPEUTIC RESPONSE UNEXPECTED6 reports
ACNE5 reports
AMNESIA5 reports
BALANCE DISORDER5 reports
BURSITIS5 reports
CHEST DISCOMFORT5 reports
DEATH5 reports
DIVERTICULITIS5 reports
DRY MOUTH5 reports
DRY SKIN5 reports
ECONOMIC PROBLEM5 reports
EYE PAIN5 reports
GASTRITIS5 reports

Key Safety Signals

  • Drug hypersensitivity reactions
  • Serious adverse events (44.8%)
  • Off-label use
  • Diverse reaction types

Patient Demographics

Adverse event reports by sex: Female: 290, Male: 135. The most frequently reported age groups are age 61 (12 reports), age 55 (9 reports), age 47 (8 reports). These demographics reflect reporting patterns and may not represent the full patient population.

Report Outcomes

Out of 460 classified reports for SULFACETAMIDE SODIUM:

  • Serious: 206 reports (44.8%) — includes hospitalization, disability, life-threatening events, or death
  • Non-Serious: 254 reports (55.2%)
Serious 44.8%Non-Serious 55.2%

The FDA classifies an adverse event as “serious” if it results in death, hospitalization, disability, congenital anomaly, or requires intervention to prevent permanent damage.

Demographics Breakdown

Reports by Sex

Female290 (68.2%)
Male135 (31.8%)

Reports by Age

Age 6112 reports
Age 559 reports
Age 478 reports
Age 628 reports
Age 497 reports
Age 517 reports
Age 346 reports
Age 426 reports
Age 756 reports
Age 786 reports
Age 305 reports
Age 435 reports
Age 485 reports
Age 545 reports
Age 575 reports
Age 585 reports
Age 595 reports
Age 605 reports
Age 635 reports
Age 695 reports

Demographics reflect voluntary FDA adverse event reporting patterns and may not represent the full patient population.

Drug Interactions & Warnings

Interactions and warnings include potential for drug hypersensitivity and off-label use, which may require careful monitoring.

What You Should Know

If you are taking Sulfacetamide Sodium, here are important things to know. The most commonly reported side effects include drug hypersensitivity, drug ineffective, dyspnoea, nausea, headache. While many of these may be mild and temporary, you should contact your healthcare provider if any symptoms are severe or persistent. Always follow prescribed usage and avoid off-label use. Report any adverse reactions to healthcare providers promptly. If you experience a serious adverse reaction, seek emergency medical attention immediately or call 911. You can report side effects to the FDA's MedWatch program at 1-800-FDA-1088.

Regulatory Context

Regulatory oversight is necessary given the high rate of serious adverse events and diverse reactions.

Frequently Asked Questions

How many adverse event reports has the FDA received for Sulfacetamide Sodium?

The FDA has received approximately 1,112 adverse event reports associated with Sulfacetamide Sodium. These reports come from healthcare professionals, consumers, and manufacturers through the FDA Adverse Event Reporting System (FAERS). Note that the number of reports does not directly indicate the frequency of side effects, as adverse events are voluntarily reported and may be underrepresented.

What are the most commonly reported side effects of Sulfacetamide Sodium?

The most frequently reported adverse events for Sulfacetamide Sodium include Drug Hypersensitivity, Drug Ineffective, Dyspnoea, Nausea, Headache. By volume, the top reported reactions are: Drug Hypersensitivity (61 reports), Drug Ineffective (43 reports), Dyspnoea (29 reports). These figures reflect FDA adverse event reports and may not represent the true incidence rate of these side effects in all patients taking Sulfacetamide Sodium.

What percentage of Sulfacetamide Sodium adverse event reports are serious?

Out of 460 classified reports, 206 (44.8%) were classified as serious and 254 as non-serious. The FDA classifies an event as "serious" if it results in death, hospitalization, disability, or other medically significant outcomes. A higher serious-event ratio warrants closer attention but does not necessarily mean the drug is unsafe.

Who reports adverse events for Sulfacetamide Sodium (by sex)?

Adverse event reports for Sulfacetamide Sodium break down by patient sex as follows: Female: 290, Male: 135. This distribution reflects reporting patterns rather than actual risk differences between groups. Reporting rates can be influenced by prescribing patterns, disease demographics, and reporting behavior.

What age groups report the most side effects for Sulfacetamide Sodium?

The most frequently reported age groups for Sulfacetamide Sodium adverse events are: age 61: 12 reports, age 55: 9 reports, age 47: 8 reports, age 62: 8 reports, age 49: 7 reports. Age-related reporting patterns can reflect both the demographics of the patient population and potential age-related susceptibility to certain side effects.

Who manufactures Sulfacetamide Sodium?

The primary manufacturer associated with Sulfacetamide Sodium adverse event reports is Bausch Health Us, Llc. Multiple manufacturers may produce generic versions of this drug. The manufacturer listed reflects the most frequently reported brand in FDA adverse event data.

What other side effects have been reported for Sulfacetamide Sodium?

Beyond the most common reactions, other reported adverse events for Sulfacetamide Sodium include: Off Label Use, Weight Decreased, Fatigue, Rash, Vomiting. Less common side effects can still be clinically significant. Patients should report any unusual symptoms to their healthcare provider.

How do I report a side effect from Sulfacetamide Sodium?

You can report adverse events from Sulfacetamide Sodium to the FDA through their MedWatch program at www.fda.gov/medwatch, by calling 1-800-FDA-1088, or by completing Form FDA 3500. Healthcare professionals, consumers, and manufacturers can all submit reports. Reporting helps the FDA monitor drug safety after approval.

What is Sulfacetamide Sodium's safety score and what does it mean?

Sulfacetamide Sodium has a safety concern score of 65 out of 100 (elevated concern). This score is calculated from the ratio of serious to non-serious adverse events, the diversity of reported reactions, and the overall volume of reports relative to usage. Drug hypersensitivity reactions are the most common serious adverse events.

What are the key safety signals for Sulfacetamide Sodium?

Key safety signals identified in Sulfacetamide Sodium's adverse event data include: Drug hypersensitivity reactions. Serious adverse events (44.8%). Off-label use. Diverse reaction types. These signals are derived from patterns in FDA reports and should be discussed with a healthcare provider for personalized assessment.

Does Sulfacetamide Sodium interact with other drugs?

Interactions and warnings include potential for drug hypersensitivity and off-label use, which may require careful monitoring. Always inform your healthcare provider about all medications, supplements, and over-the-counter drugs you are taking before starting Sulfacetamide Sodium.

What should patients know before taking Sulfacetamide Sodium?

Always follow prescribed usage and avoid off-label use. Report any adverse reactions to healthcare providers promptly.

Are Sulfacetamide Sodium side effects well-documented?

Sulfacetamide Sodium has 1,112 adverse event reports on file with the FDA. A wide range of reactions indicates potential for diverse side effects. The volume of reports for Sulfacetamide Sodium reflects both the drug's usage level and the vigilance of the reporting community.

What is the FDA's position on Sulfacetamide Sodium?

Regulatory oversight is necessary given the high rate of serious adverse events and diverse reactions. For the most current regulatory information, check the FDA's drug labeling database or consult your pharmacist.

Related Drugs

Drugs related to SULFACETAMIDE SODIUM based on therapeutic use, drug class, or shared indications:

Drug1: PenicillinsDrug2: CephalosporinsDrug3: VancomycinDrug4: AminoglycosidesDrug5: Fluoroquinolones
Important Disclaimer: This content is generated by AI analysis of FDA adverse event reports and is provided for informational purposes only. It is not medical advice. Adverse event reports submitted to the FDA do not prove that a medication caused the reported side effect. Always consult your healthcare provider before starting, stopping, or changing any medication. If you experience a serious side effect, contact your doctor or call 911 immediately.