VISMODEGIB

N/A

Manufactured by Genentech, Inc.

17,013 FDA adverse event reports analyzed

Last updated: 2026-04-14

About VISMODEGIB

VISMODEGIB is a medication tracked in the FDA Adverse Event Reporting System (FAERS), manufactured by Genentech, Inc.. The most commonly reported adverse reactions for VISMODEGIB include MUSCLE SPASMS, ALOPECIA, AGEUSIA, FATIGUE, DYSGEUSIA. This page provides a comprehensive breakdown of reported side effects, safety signals, patient demographics, and AI-powered safety analysis for VISMODEGIB.

Top Adverse Reactions

MUSCLE SPASMS2,025 reports
ALOPECIA1,384 reports
AGEUSIA994 reports
FATIGUE954 reports
DYSGEUSIA740 reports
DEATH731 reports
WEIGHT DECREASED730 reports
NAUSEA704 reports
DECREASED APPETITE696 reports
DIARRHOEA469 reports
CONSTIPATION377 reports
OFF LABEL USE364 reports
ASTHENIA290 reports
ARTHRALGIA276 reports
VOMITING257 reports
NO ADVERSE EVENT254 reports
PAIN242 reports
TASTE DISORDER234 reports
MYALGIA211 reports
DRUG INEFFECTIVE189 reports
HEADACHE179 reports
MALAISE160 reports
FALL138 reports
RASH136 reports
BASAL CELL CARCINOMA135 reports
DIZZINESS130 reports
DEHYDRATION129 reports
ABDOMINAL PAIN UPPER118 reports
DYSPNOEA113 reports
SQUAMOUS CELL CARCINOMA110 reports
DISEASE PROGRESSION104 reports
INSOMNIA104 reports
INTENTIONAL PRODUCT USE ISSUE104 reports
PRURITUS104 reports
ABDOMINAL DISCOMFORT95 reports
ABDOMINAL PAIN90 reports
ANAEMIA90 reports
PNEUMONIA90 reports
PAIN IN EXTREMITY89 reports
DYSPHAGIA81 reports
PYREXIA81 reports
BACK PAIN79 reports
CEREBROVASCULAR ACCIDENT73 reports
URINARY TRACT INFECTION69 reports
DEPRESSION67 reports
COUGH63 reports
ILL DEFINED DISORDER63 reports
HEPATIC ENZYME INCREASED60 reports
HYPONATRAEMIA60 reports
MADAROSIS59 reports
NEOPLASM MALIGNANT59 reports
NEUTROPHIL COUNT DECREASED55 reports
WHITE BLOOD CELL COUNT DECREASED54 reports
DRUG INTERACTION53 reports
DYSPEPSIA52 reports
HYPOAESTHESIA52 reports
MYOCARDIAL INFARCTION51 reports
CONFUSIONAL STATE48 reports
ANOSMIA47 reports
HYPOGEUSIA47 reports
COVID 1945 reports
SEPSIS44 reports
SOMNOLENCE44 reports
MEMORY IMPAIRMENT42 reports
ANXIETY41 reports
GASTROINTESTINAL DISORDER41 reports
MUSCULAR WEAKNESS41 reports
PERIPHERAL SWELLING41 reports
THERAPY CESSATION39 reports
NASOPHARYNGITIS38 reports
PLATELET COUNT DECREASED38 reports
DEAFNESS37 reports
DRY MOUTH37 reports
FEELING ABNORMAL37 reports
HYPOTENSION37 reports
GAIT DISTURBANCE36 reports
THROMBOSIS36 reports
HYPERTENSION35 reports
PRODUCT DOSE OMISSION ISSUE35 reports
CHEST PAIN34 reports
DRUG INTOLERANCE34 reports
GASTRIC DISORDER34 reports
HEPATOTOXICITY34 reports
INFECTION34 reports
ABDOMINAL DISTENSION33 reports
DRUG DOSE OMISSION33 reports
NEOPLASM33 reports
DRY SKIN31 reports
LYMPHOCYTE COUNT DECREASED31 reports
PARAESTHESIA31 reports
SEIZURE31 reports
SYNCOPE31 reports
GASTROOESOPHAGEAL REFLUX DISEASE30 reports
RENAL FAILURE30 reports
ERYTHEMA29 reports
HIP FRACTURE29 reports
ILLNESS29 reports
JAUNDICE29 reports
TREMOR29 reports
AMNESIA28 reports

Report Outcomes

Out of 8,687 classified reports for VISMODEGIB:

Serious 42.7%Non-Serious 57.3%

The FDA classifies an adverse event as “serious” if it results in death, hospitalization, disability, congenital anomaly, or requires intervention to prevent permanent damage.

Demographics Breakdown

Reports by Sex

Male4,868 (60.3%)
Female3,182 (39.4%)
Unknown17 (0.2%)

Reports by Age

Age 78115 reports
Age 65112 reports
Age 62105 reports
Age 85101 reports
Age 7599 reports
Age 7796 reports
Age 6895 reports
Age 8095 reports
Age 6694 reports
Age 7394 reports
Age 7494 reports
Age 8494 reports
Age 7093 reports
Age 8392 reports
Age 6191 reports
Age 7291 reports
Age 7990 reports
Age 7688 reports
Age 8784 reports
Age 6083 reports

Demographics reflect voluntary FDA adverse event reporting patterns and may not represent the full patient population.

Frequently Asked Questions

How many FDA adverse event reports are associated with VISMODEGIB?

This profile reflects 17,013 FDA FAERS reports that mention VISMODEGIB. Reporting is voluntary and does not prove that the drug caused any listed event.

Which adverse reactions are most often listed for VISMODEGIB?

Frequently reported terms in FAERS include MUSCLE SPASMS, ALOPECIA, AGEUSIA, FATIGUE, DYSGEUSIA, DEATH. Rankings reflect reporting volume in this dataset, not confirmed side effect rates in the general population.

Who manufactures VISMODEGIB?

Labeling and FAERS entries often list Genentech, Inc. in connection with VISMODEGIB. Always verify the specific product and NDC with your pharmacist.

Important Disclaimer: This content is generated by AI analysis of FDA adverse event reports and is provided for informational purposes only. It is not medical advice. Adverse event reports submitted to the FDA do not prove that a medication caused the reported side effect. Always consult your healthcare provider before starting, stopping, or changing any medication. If you experience a serious side effect, contact your doctor or call 911 immediately.