ADALIMUMAB FKJP

72/100 · Elevated

Manufactured by Biocon Biologics Inc

Adalimumab-FKJP Safety Profile: Common Reactions and Warnings

281,217 FDA adverse event reports analyzed

Last updated: 2026-05-12

About ADALIMUMAB FKJP

ADALIMUMAB FKJP is a medication tracked in the FDA Adverse Event Reporting System (FAERS), manufactured by Biocon Biologics Inc. Based on analysis of 281,217 FDA adverse event reports, ADALIMUMAB FKJP has a safety score of 72 out of 100. This score indicates a relatively favorable safety profile, with fewer or less severe adverse events compared to many other tracked medications. The most commonly reported adverse reactions for ADALIMUMAB FKJP include DRUG INEFFECTIVE, OFF LABEL USE, RHEUMATOID ARTHRITIS, PAIN, FATIGUE. This page provides a comprehensive breakdown of reported side effects, safety signals, patient demographics, and AI-powered safety analysis for ADALIMUMAB FKJP.

AI Safety Analysis

Adalimumab-Fkjp has a safety concern score of 72 out of 100, placing it in the elevated concern category based on analysis of FDA adverse event data. The FDA has received approximately 281,217 adverse event reports for this medication, which is primarily manufactured by Biocon Biologics Inc.

The most commonly reported adverse events include Drug Ineffective, Off Label Use, Rheumatoid Arthritis. Of classified reports, 95.4% were designated as serious by the FDA, meaning they involved hospitalization, disability, or other significant medical outcomes. The most common reactions include pain, fatigue, and rash, indicating a broad range of potential side effects.

Serious reactions such as systemic lupus erythematosus and pericarditis are reported, but occur less frequently. Drug intolerance and treatment failure are significant concerns, affecting a substantial portion of users.

Patients taking Adalimumab-Fkjp should monitor for the commonly reported side effects and contact their healthcare provider if they experience any unusual symptoms. Adalimumab-FKJP may interact with other immunosuppressants, and patients should be monitored for signs of infection and other adverse reactions. This analysis is based on voluntary FDA adverse event reports and should not replace professional medical advice.

Safety Score: 72/100

Adalimumab-Fkjp received a safety concern score of 72/100 (elevated concern). This is based on a 95.4% serious event ratio across 42,143 classified reports. The score accounts for 281,217 total adverse event reports and 100 distinct reaction types. This elevated score indicates a notable proportion of serious adverse events and warrants careful monitoring.

Top Adverse Reactions

DRUG INEFFECTIVE10,138 reports
OFF LABEL USE7,909 reports
RHEUMATOID ARTHRITIS5,480 reports
PAIN5,195 reports
FATIGUE5,160 reports
ARTHRALGIA4,922 reports
RASH4,358 reports
CONDITION AGGRAVATED4,174 reports
DRUG INTOLERANCE4,052 reports
SYSTEMIC LUPUS ERYTHEMATOSUS3,890 reports
NAUSEA3,850 reports
DIARRHOEA3,835 reports
JOINT SWELLING3,826 reports
HEADACHE3,747 reports
ALOPECIA3,706 reports
ABDOMINAL DISCOMFORT3,683 reports
SYNOVITIS3,678 reports
TREATMENT FAILURE3,601 reports
PSORIATIC ARTHROPATHY3,555 reports
ARTHROPATHY3,518 reports
GLOSSODYNIA3,453 reports
PEMPHIGUS3,367 reports
INFUSION RELATED REACTION3,314 reports
MALAISE3,296 reports
SWELLING3,273 reports
HAND DEFORMITY3,226 reports
GENERAL PHYSICAL HEALTH DETERIORATION3,160 reports
CONTRAINDICATED PRODUCT ADMINISTERED3,134 reports
VOMITING3,109 reports
HYPERSENSITIVITY3,103 reports
WOUND3,093 reports
HYPERTENSION3,037 reports
PYREXIA2,987 reports
THERAPEUTIC PRODUCT EFFECT DECREASED2,933 reports
MATERNAL EXPOSURE DURING PREGNANCY2,920 reports
MOBILITY DECREASED2,872 reports
DRUG HYPERSENSITIVITY2,861 reports
HEPATIC ENZYME INCREASED2,844 reports
MUSCULOSKELETAL STIFFNESS2,826 reports
INFECTION2,748 reports
PERICARDITIS2,737 reports
PRODUCT USE ISSUE2,694 reports
CROHN^S DISEASE2,631 reports
INTENTIONAL PRODUCT USE ISSUE2,611 reports
HYPOAESTHESIA2,605 reports
DIZZINESS2,574 reports
ANTI CYCLIC CITRULLINATED PEPTIDE ANTIBODY POSITIVE2,573 reports
FIBROMYALGIA2,531 reports
PNEUMONIA2,529 reports
TYPE 2 DIABETES MELLITUS2,515 reports
HELICOBACTER INFECTION2,500 reports
DUODENAL ULCER PERFORATION2,482 reports
DYSPNOEA2,458 reports
PAIN IN EXTREMITY2,455 reports
PRODUCT USE IN UNAPPROVED INDICATION2,445 reports
PERIPHERAL SWELLING2,376 reports
DISCOMFORT2,371 reports
FOLLICULITIS2,310 reports
WEIGHT INCREASED2,308 reports
URTICARIA2,262 reports
INJURY2,239 reports
BLISTER2,238 reports
IMPAIRED HEALING2,235 reports
BLOOD CHOLESTEROL INCREASED2,234 reports
C REACTIVE PROTEIN INCREASED2,213 reports
NASOPHARYNGITIS2,197 reports
ABDOMINAL PAIN UPPER2,188 reports
INFLAMMATION2,171 reports
LIVER INJURY2,170 reports
CONFUSIONAL STATE2,160 reports
PRURITUS2,143 reports
ASTHENIA2,110 reports
IRRITABLE BOWEL SYNDROME2,103 reports
DECREASED APPETITE2,091 reports
WHEEZING2,048 reports
RHEUMATOID FACTOR POSITIVE2,043 reports
INSOMNIA2,039 reports
GASTROINTESTINAL DISORDER2,035 reports
STOMATITIS2,028 reports
RHEUMATIC FEVER2,009 reports
ABDOMINAL PAIN1,990 reports
OSTEOARTHRITIS1,897 reports
THERAPEUTIC PRODUCT EFFECT INCOMPLETE1,869 reports
LOWER RESPIRATORY TRACT INFECTION1,867 reports
ARTHRITIS1,865 reports
DEPRESSION1,840 reports
PSORIASIS1,835 reports
ILL DEFINED DISORDER1,797 reports
MUSCLE INJURY1,788 reports
JOINT RANGE OF MOTION DECREASED1,785 reports
SLEEP DISORDER1,776 reports
SINUSITIS1,717 reports
C REACTIVE PROTEIN ABNORMAL1,651 reports
DYSPEPSIA1,630 reports
GAIT INABILITY1,614 reports
WEIGHT DECREASED1,584 reports
THERAPY NON RESPONDER1,580 reports
DRY MOUTH1,574 reports
BURSITIS1,550 reports
OEDEMA1,514 reports

Key Safety Signals

  • Systemic lupus erythematosus and pericarditis are key safety signals, though less common.
  • Drug intolerance and treatment failure are notable safety signals, affecting a significant number of patients.
  • Infections, particularly pneumonia and lower respiratory tract infections, are frequent but generally non-serious.

Patient Demographics

Adverse event reports by sex: Female: 21,551, Male: 10,432, Unknown: 86. The most frequently reported age groups are age 43 (1,604 reports), age 44 (1,410 reports), age 40 (1,127 reports). These demographics reflect reporting patterns and may not represent the full patient population.

Report Outcomes

Out of 42,143 classified reports for ADALIMUMAB FKJP:

  • Serious: 40,186 reports (95.4%) — includes hospitalization, disability, life-threatening events, or death
  • Non-Serious: 1,957 reports (4.6%)
Serious 95.4%Non-Serious 4.6%

The FDA classifies an adverse event as “serious” if it results in death, hospitalization, disability, congenital anomaly, or requires intervention to prevent permanent damage.

Demographics Breakdown

Reports by Sex

Female21,551 (67.2%)
Male10,432 (32.5%)
Unknown86 (0.3%)

Reports by Age

Age 431,604 reports
Age 441,410 reports
Age 401,127 reports
Age 59685 reports
Age 56560 reports
Age 58541 reports
Age 47513 reports
Age 65506 reports
Age 53487 reports
Age 54487 reports
Age 63480 reports
Age 48450 reports
Age 50439 reports
Age 64432 reports
Age 57426 reports
Age 60425 reports
Age 62422 reports
Age 49416 reports
Age 52407 reports
Age 41393 reports

Demographics reflect voluntary FDA adverse event reporting patterns and may not represent the full patient population.

Drug Interactions & Warnings

Adalimumab-FKJP may interact with other immunosuppressants, and patients should be monitored for signs of infection and other adverse reactions.

What You Should Know

If you are taking Adalimumab-Fkjp, here are important things to know. The most commonly reported side effects include drug ineffective, off label use, rheumatoid arthritis, pain, fatigue. While many of these may be mild and temporary, you should contact your healthcare provider if any symptoms are severe or persistent. Patients should report any new or worsening symptoms to their healthcare provider immediately. Regular monitoring for signs of infection and other serious adverse reactions is recommended. If you experience a serious adverse reaction, seek emergency medical attention immediately or call 911. You can report side effects to the FDA's MedWatch program at 1-800-FDA-1088.

Regulatory Context

The FDA continues to monitor the safety of adalimumab-FKJP, and updates will be provided based on ongoing studies and reports.

Frequently Asked Questions

How many adverse event reports has the FDA received for Adalimumab-Fkjp?

The FDA has received approximately 281,217 adverse event reports associated with Adalimumab-Fkjp. These reports come from healthcare professionals, consumers, and manufacturers through the FDA Adverse Event Reporting System (FAERS). Note that the number of reports does not directly indicate the frequency of side effects, as adverse events are voluntarily reported and may be underrepresented.

What are the most commonly reported side effects of Adalimumab-Fkjp?

The most frequently reported adverse events for Adalimumab-Fkjp include Drug Ineffective, Off Label Use, Rheumatoid Arthritis, Pain, Fatigue. By volume, the top reported reactions are: Drug Ineffective (10,138 reports), Off Label Use (7,909 reports), Rheumatoid Arthritis (5,480 reports). These figures reflect FDA adverse event reports and may not represent the true incidence rate of these side effects in all patients taking Adalimumab-Fkjp.

What percentage of Adalimumab-Fkjp adverse event reports are serious?

Out of 42,143 classified reports, 40,186 (95.4%) were classified as serious and 1,957 as non-serious. The FDA classifies an event as "serious" if it results in death, hospitalization, disability, or other medically significant outcomes. A higher serious-event ratio warrants closer attention but does not necessarily mean the drug is unsafe.

Who reports adverse events for Adalimumab-Fkjp (by sex)?

Adverse event reports for Adalimumab-Fkjp break down by patient sex as follows: Female: 21,551, Male: 10,432, Unknown: 86. This distribution reflects reporting patterns rather than actual risk differences between groups. Reporting rates can be influenced by prescribing patterns, disease demographics, and reporting behavior.

What age groups report the most side effects for Adalimumab-Fkjp?

The most frequently reported age groups for Adalimumab-Fkjp adverse events are: age 43: 1,604 reports, age 44: 1,410 reports, age 40: 1,127 reports, age 59: 685 reports, age 56: 560 reports. Age-related reporting patterns can reflect both the demographics of the patient population and potential age-related susceptibility to certain side effects.

Who manufactures Adalimumab-Fkjp?

The primary manufacturer associated with Adalimumab-Fkjp adverse event reports is Biocon Biologics Inc. Multiple manufacturers may produce generic versions of this drug. The manufacturer listed reflects the most frequently reported brand in FDA adverse event data.

What other side effects have been reported for Adalimumab-Fkjp?

Beyond the most common reactions, other reported adverse events for Adalimumab-Fkjp include: Arthralgia, Rash, Condition Aggravated, Drug Intolerance, Systemic Lupus Erythematosus. Less common side effects can still be clinically significant. Patients should report any unusual symptoms to their healthcare provider.

How do I report a side effect from Adalimumab-Fkjp?

You can report adverse events from Adalimumab-Fkjp to the FDA through their MedWatch program at www.fda.gov/medwatch, by calling 1-800-FDA-1088, or by completing Form FDA 3500. Healthcare professionals, consumers, and manufacturers can all submit reports. Reporting helps the FDA monitor drug safety after approval.

What is Adalimumab-Fkjp's safety score and what does it mean?

Adalimumab-Fkjp has a safety concern score of 72 out of 100 (elevated concern). This score is calculated from the ratio of serious to non-serious adverse events, the diversity of reported reactions, and the overall volume of reports relative to usage. The most common reactions include pain, fatigue, and rash, indicating a broad range of potential side effects.

What are the key safety signals for Adalimumab-Fkjp?

Key safety signals identified in Adalimumab-Fkjp's adverse event data include: Systemic lupus erythematosus and pericarditis are key safety signals, though less common.. Drug intolerance and treatment failure are notable safety signals, affecting a significant number of patients.. Infections, particularly pneumonia and lower respiratory tract infections, are frequent but generally non-serious.. These signals are derived from patterns in FDA reports and should be discussed with a healthcare provider for personalized assessment.

Does Adalimumab-Fkjp interact with other drugs?

Adalimumab-FKJP may interact with other immunosuppressants, and patients should be monitored for signs of infection and other adverse reactions. Always inform your healthcare provider about all medications, supplements, and over-the-counter drugs you are taking before starting Adalimumab-Fkjp.

What should patients know before taking Adalimumab-Fkjp?

Patients should report any new or worsening symptoms to their healthcare provider immediately. Regular monitoring for signs of infection and other serious adverse reactions is recommended.

Are Adalimumab-Fkjp side effects well-documented?

Adalimumab-Fkjp has 281,217 adverse event reports on file with the FDA. Serious reactions such as systemic lupus erythematosus and pericarditis are reported, but occur less frequently. The volume of reports for Adalimumab-Fkjp reflects both the drug's usage level and the vigilance of the reporting community.

What is the FDA's position on Adalimumab-Fkjp?

The FDA continues to monitor the safety of adalimumab-FKJP, and updates will be provided based on ongoing studies and reports. For the most current regulatory information, check the FDA's drug labeling database or consult your pharmacist.

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Important Disclaimer: This content is generated by AI analysis of FDA adverse event reports and is provided for informational purposes only. It is not medical advice. Adverse event reports submitted to the FDA do not prove that a medication caused the reported side effect. Always consult your healthcare provider before starting, stopping, or changing any medication. If you experience a serious side effect, contact your doctor or call 911 immediately.