ATORVASTATIN CALCIUM, FILM COATED

72/100 · Elevated

Manufactured by Accord Healthcare Inc.

Moderate Safety Concerns with Atorvastatin Calcium

126,371 FDA adverse event reports analyzed

Last updated: 2026-05-12

About ATORVASTATIN CALCIUM, FILM COATED

ATORVASTATIN CALCIUM, FILM COATED is a medication tracked in the FDA Adverse Event Reporting System (FAERS), manufactured by Accord Healthcare Inc.. Based on analysis of 126,371 FDA adverse event reports, ATORVASTATIN CALCIUM, FILM COATED has a safety score of 72 out of 100. This score indicates a relatively favorable safety profile, with fewer or less severe adverse events compared to many other tracked medications. The most commonly reported adverse reactions for ATORVASTATIN CALCIUM, FILM COATED include FATIGUE, DRUG INEFFECTIVE, DIARRHOEA, NAUSEA, DYSPNOEA. This page provides a comprehensive breakdown of reported side effects, safety signals, patient demographics, and AI-powered safety analysis for ATORVASTATIN CALCIUM, FILM COATED.

AI Safety Analysis

Atorvastatin Calcium, Film Coated has a safety concern score of 72 out of 100, placing it in the elevated concern category based on analysis of FDA adverse event data. The FDA has received approximately 126,371 adverse event reports for this medication, which is primarily manufactured by Accord Healthcare Inc..

The most commonly reported adverse events include Fatigue, Drug Ineffective, Diarrhoea. Of classified reports, 63.4% were designated as serious by the FDA, meaning they involved hospitalization, disability, or other significant medical outcomes. Fatigue, nausea, and dizziness are the most frequently reported adverse events.

Serious adverse events, such as falls and pneumonia, are common. Drug interactions and hypersensitivity reactions are also significant concerns.

Patients taking Atorvastatin Calcium, Film Coated should monitor for the commonly reported side effects and contact their healthcare provider if they experience any unusual symptoms. Atorvastatin can interact with other drugs, and patients should be warned about potential drug interactions and hypersensitivity reactions. This analysis is based on voluntary FDA adverse event reports and should not replace professional medical advice.

Safety Score: 72/100

Atorvastatin Calcium, Film Coated received a safety concern score of 72/100 (elevated concern). This is based on a 63.4% serious event ratio across 65,790 classified reports. The score accounts for 126,371 total adverse event reports and 100 distinct reaction types. This elevated score indicates a notable proportion of serious adverse events and warrants careful monitoring.

Top Adverse Reactions

FATIGUE4,361 reports
DRUG INEFFECTIVE4,158 reports
DIARRHOEA3,794 reports
NAUSEA3,556 reports
DYSPNOEA3,436 reports
HEADACHE3,107 reports
DIZZINESS2,789 reports
PAIN2,713 reports
OFF LABEL USE2,676 reports
ASTHENIA2,420 reports
MYALGIA2,413 reports
ARTHRALGIA2,381 reports
FALL2,332 reports
COUGH2,276 reports
MALAISE2,258 reports
PRURITUS2,031 reports
DEATH2,002 reports
WEIGHT DECREASED1,962 reports
PAIN IN EXTREMITY1,903 reports
VOMITING1,877 reports
PNEUMONIA1,815 reports
RASH1,729 reports
PRODUCT DOSE OMISSION ISSUE1,704 reports
PYREXIA1,638 reports
DRUG INTERACTION1,570 reports
DRUG HYPERSENSITIVITY1,548 reports
DECREASED APPETITE1,446 reports
MUSCLE SPASMS1,420 reports
INSOMNIA1,396 reports
CONSTIPATION1,391 reports
BACK PAIN1,302 reports
HYPOTENSION1,287 reports
CONDITION AGGRAVATED1,194 reports
CHEST PAIN1,193 reports
ABDOMINAL PAIN1,159 reports
PERIPHERAL SWELLING1,153 reports
BLOOD PRESSURE INCREASED1,136 reports
COVID 191,105 reports
GAIT DISTURBANCE1,083 reports
ABDOMINAL PAIN UPPER1,069 reports
HYPERTENSION1,068 reports
ABDOMINAL DISCOMFORT1,061 reports
URINARY TRACT INFECTION1,055 reports
ANAEMIA1,031 reports
MYOCARDIAL INFARCTION1,021 reports
NASOPHARYNGITIS1,021 reports
TYPE 2 DIABETES MELLITUS1,007 reports
EYE PAIN976 reports
SOMNOLENCE974 reports
MUSCULAR WEAKNESS952 reports
FEELING ABNORMAL940 reports
CEREBROVASCULAR ACCIDENT918 reports
CONFUSIONAL STATE895 reports
RHABDOMYOLYSIS893 reports
WEIGHT INCREASED861 reports
ANXIETY860 reports
PRODUCT USE IN UNAPPROVED INDICATION860 reports
ERYTHEMA855 reports
INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION843 reports
ACUTE KIDNEY INJURY834 reports
HAEMOGLOBIN DECREASED801 reports
ATRIAL FIBRILLATION786 reports
OEDEMA PERIPHERAL780 reports
DEPRESSION768 reports
RENAL FAILURE760 reports
SYNCOPE751 reports
DEHYDRATION734 reports
VISION BLURRED732 reports
BLOOD GLUCOSE INCREASED722 reports
SINUSITIS722 reports
DYSPEPSIA714 reports
CHILLS713 reports
MACULAR DEGENERATION701 reports
PARAESTHESIA677 reports
OXYGEN SATURATION DECREASED670 reports
CHEST DISCOMFORT667 reports
HYPOAESTHESIA654 reports
INFLUENZA652 reports
MEMORY IMPAIRMENT636 reports
ILLNESS635 reports
SEPSIS617 reports
INJECTION SITE PAIN605 reports
HYPERSENSITIVITY604 reports
JOINT SWELLING604 reports
HEART RATE INCREASED599 reports
CARDIAC FAILURE587 reports
DRUG INTOLERANCE586 reports
TREMOR582 reports
NEUROPATHY PERIPHERAL574 reports
LOSS OF CONSCIOUSNESS568 reports
PALPITATIONS556 reports
CARDIAC DISORDER550 reports
DYSPNOEA EXERTIONAL550 reports
INFECTION549 reports
ALOPECIA545 reports
ASTHMA545 reports
PLATELET COUNT DECREASED545 reports
RHINORRHOEA542 reports
HYPERHIDROSIS540 reports
PRODUCT USE ISSUE540 reports

Key Safety Signals

  • Falls and pneumonia are among the more serious adverse events.
  • Drug interactions and hypersensitivity reactions are key safety signals.
  • Rhabdomyolysis and myocardial infarction are rare but serious adverse events.

Patient Demographics

Adverse event reports by sex: Female: 31,709, Male: 29,507, Unknown: 86. The most frequently reported age groups are age 65 (1,440 reports), age 71 (1,421 reports), age 75 (1,409 reports). These demographics reflect reporting patterns and may not represent the full patient population.

Report Outcomes

Out of 65,790 classified reports for ATORVASTATIN CALCIUM, FILM COATED:

  • Serious: 41,711 reports (63.4%) — includes hospitalization, disability, life-threatening events, or death
  • Non-Serious: 24,079 reports (36.6%)
Serious 63.4%Non-Serious 36.6%

The FDA classifies an adverse event as “serious” if it results in death, hospitalization, disability, congenital anomaly, or requires intervention to prevent permanent damage.

Demographics Breakdown

Reports by Sex

Female31,709 (51.7%)
Male29,507 (48.1%)
Unknown86 (0.1%)

Reports by Age

Age 651,440 reports
Age 711,421 reports
Age 751,409 reports
Age 701,408 reports
Age 661,355 reports
Age 721,330 reports
Age 681,328 reports
Age 691,310 reports
Age 741,309 reports
Age 671,275 reports
Age 731,233 reports
Age 641,231 reports
Age 611,229 reports
Age 621,213 reports
Age 631,199 reports
Age 771,102 reports
Age 761,099 reports
Age 601,082 reports
Age 781,075 reports
Age 58981 reports

Demographics reflect voluntary FDA adverse event reporting patterns and may not represent the full patient population.

Drug Interactions & Warnings

Atorvastatin can interact with other drugs, and patients should be warned about potential drug interactions and hypersensitivity reactions.

What You Should Know

If you are taking Atorvastatin Calcium, Film Coated, here are important things to know. The most commonly reported side effects include fatigue, drug ineffective, diarrhoea, nausea, dyspnoea. While many of these may be mild and temporary, you should contact your healthcare provider if any symptoms are severe or persistent. Discuss any other medications you are taking with your healthcare provider to avoid potential drug interactions. Monitor for signs of serious adverse events such as falls, pneumonia, and muscle pain. If you experience a serious adverse reaction, seek emergency medical attention immediately or call 911. You can report side effects to the FDA's MedWatch program at 1-800-FDA-1088.

Regulatory Context

Regulatory oversight is ongoing, with a focus on monitoring serious adverse events and drug interactions.

Frequently Asked Questions

How many adverse event reports has the FDA received for Atorvastatin Calcium, Film Coated?

The FDA has received approximately 126,371 adverse event reports associated with Atorvastatin Calcium, Film Coated. These reports come from healthcare professionals, consumers, and manufacturers through the FDA Adverse Event Reporting System (FAERS). Note that the number of reports does not directly indicate the frequency of side effects, as adverse events are voluntarily reported and may be underrepresented.

What are the most commonly reported side effects of Atorvastatin Calcium, Film Coated?

The most frequently reported adverse events for Atorvastatin Calcium, Film Coated include Fatigue, Drug Ineffective, Diarrhoea, Nausea, Dyspnoea. By volume, the top reported reactions are: Fatigue (4,361 reports), Drug Ineffective (4,158 reports), Diarrhoea (3,794 reports). These figures reflect FDA adverse event reports and may not represent the true incidence rate of these side effects in all patients taking Atorvastatin Calcium, Film Coated.

What percentage of Atorvastatin Calcium, Film Coated adverse event reports are serious?

Out of 65,790 classified reports, 41,711 (63.4%) were classified as serious and 24,079 as non-serious. The FDA classifies an event as "serious" if it results in death, hospitalization, disability, or other medically significant outcomes. A higher serious-event ratio warrants closer attention but does not necessarily mean the drug is unsafe.

Who reports adverse events for Atorvastatin Calcium, Film Coated (by sex)?

Adverse event reports for Atorvastatin Calcium, Film Coated break down by patient sex as follows: Female: 31,709, Male: 29,507, Unknown: 86. This distribution reflects reporting patterns rather than actual risk differences between groups. Reporting rates can be influenced by prescribing patterns, disease demographics, and reporting behavior.

What age groups report the most side effects for Atorvastatin Calcium, Film Coated?

The most frequently reported age groups for Atorvastatin Calcium, Film Coated adverse events are: age 65: 1,440 reports, age 71: 1,421 reports, age 75: 1,409 reports, age 70: 1,408 reports, age 66: 1,355 reports. Age-related reporting patterns can reflect both the demographics of the patient population and potential age-related susceptibility to certain side effects.

Who manufactures Atorvastatin Calcium, Film Coated?

The primary manufacturer associated with Atorvastatin Calcium, Film Coated adverse event reports is Accord Healthcare Inc.. Multiple manufacturers may produce generic versions of this drug. The manufacturer listed reflects the most frequently reported brand in FDA adverse event data.

What other side effects have been reported for Atorvastatin Calcium, Film Coated?

Beyond the most common reactions, other reported adverse events for Atorvastatin Calcium, Film Coated include: Headache, Dizziness, Pain, Off Label Use, Asthenia. Less common side effects can still be clinically significant. Patients should report any unusual symptoms to their healthcare provider.

How do I report a side effect from Atorvastatin Calcium, Film Coated?

You can report adverse events from Atorvastatin Calcium, Film Coated to the FDA through their MedWatch program at www.fda.gov/medwatch, by calling 1-800-FDA-1088, or by completing Form FDA 3500. Healthcare professionals, consumers, and manufacturers can all submit reports. Reporting helps the FDA monitor drug safety after approval.

What is Atorvastatin Calcium, Film Coated's safety score and what does it mean?

Atorvastatin Calcium, Film Coated has a safety concern score of 72 out of 100 (elevated concern). This score is calculated from the ratio of serious to non-serious adverse events, the diversity of reported reactions, and the overall volume of reports relative to usage. Fatigue, nausea, and dizziness are the most frequently reported adverse events.

What are the key safety signals for Atorvastatin Calcium, Film Coated?

Key safety signals identified in Atorvastatin Calcium, Film Coated's adverse event data include: Falls and pneumonia are among the more serious adverse events.. Drug interactions and hypersensitivity reactions are key safety signals.. Rhabdomyolysis and myocardial infarction are rare but serious adverse events.. These signals are derived from patterns in FDA reports and should be discussed with a healthcare provider for personalized assessment.

Does Atorvastatin Calcium, Film Coated interact with other drugs?

Atorvastatin can interact with other drugs, and patients should be warned about potential drug interactions and hypersensitivity reactions. Always inform your healthcare provider about all medications, supplements, and over-the-counter drugs you are taking before starting Atorvastatin Calcium, Film Coated.

What should patients know before taking Atorvastatin Calcium, Film Coated?

Discuss any other medications you are taking with your healthcare provider to avoid potential drug interactions. Monitor for signs of serious adverse events such as falls, pneumonia, and muscle pain.

Are Atorvastatin Calcium, Film Coated side effects well-documented?

Atorvastatin Calcium, Film Coated has 126,371 adverse event reports on file with the FDA. Serious adverse events, such as falls and pneumonia, are common. The volume of reports for Atorvastatin Calcium, Film Coated reflects both the drug's usage level and the vigilance of the reporting community.

What is the FDA's position on Atorvastatin Calcium, Film Coated?

Regulatory oversight is ongoing, with a focus on monitoring serious adverse events and drug interactions. For the most current regulatory information, check the FDA's drug labeling database or consult your pharmacist.

Related Drugs

Drugs related to ATORVASTATIN CALCIUM, FILM COATED based on therapeutic use, drug class, or shared indications:

SimvastatinRosuvastatinPravastatinFluvastatinPitavastatin
Important Disclaimer: This content is generated by AI analysis of FDA adverse event reports and is provided for informational purposes only. It is not medical advice. Adverse event reports submitted to the FDA do not prove that a medication caused the reported side effect. Always consult your healthcare provider before starting, stopping, or changing any medication. If you experience a serious side effect, contact your doctor or call 911 immediately.