IBUPROFEN CAPSULES 200 MG

65/100 · Elevated

Manufactured by HART Health

Moderate Safety Concerns with Ibuprofen Capsules 200 mg

482,848 FDA adverse event reports analyzed

Last updated: 2026-05-12

About IBUPROFEN CAPSULES 200 MG

IBUPROFEN CAPSULES 200 MG is a medication tracked in the FDA Adverse Event Reporting System (FAERS), manufactured by HART Health. Based on analysis of 482,848 FDA adverse event reports, IBUPROFEN CAPSULES 200 MG has a safety score of 65 out of 100. This moderate score indicates a notable volume of adverse event reports that patients and providers should be aware of. The most commonly reported adverse reactions for IBUPROFEN CAPSULES 200 MG include DRUG INEFFECTIVE, PAIN, FATIGUE, NAUSEA, HEADACHE. This page provides a comprehensive breakdown of reported side effects, safety signals, patient demographics, and AI-powered safety analysis for IBUPROFEN CAPSULES 200 MG.

AI Safety Analysis

Ibuprofen Capsules 200 Mg has a safety concern score of 65 out of 100, placing it in the elevated concern category based on analysis of FDA adverse event data. The FDA has received approximately 482,848 adverse event reports for this medication, which is primarily manufactured by Hart Health.

The most commonly reported adverse events include Drug Ineffective, Pain, Fatigue. Of classified reports, 72.9% were designated as serious by the FDA, meaning they involved hospitalization, disability, or other significant medical outcomes. The most common reactions include pain, fatigue, and nausea, indicating a broad range of mild to moderate side effects.

Serious reactions such as acute kidney injury and drug hypersensitivity are reported, but less frequently. There is a notable increase in gastrointestinal and respiratory issues, suggesting potential risks in these areas.

Patients taking Ibuprofen Capsules 200 Mg should monitor for the commonly reported side effects and contact their healthcare provider if they experience any unusual symptoms. Ibuprofen can interact with other medications, potentially increasing the risk of side effects. Patients should consult a healthcare provider before combining it with other drugs. This analysis is based on voluntary FDA adverse event reports and should not replace professional medical advice.

Safety Score: 65/100

Ibuprofen Capsules 200 Mg received a safety concern score of 65/100 (elevated concern). This is based on a 72.9% serious event ratio across 191,770 classified reports. The score accounts for 482,848 total adverse event reports and 100 distinct reaction types. This elevated score indicates a notable proportion of serious adverse events and warrants careful monitoring.

Top Adverse Reactions

DRUG INEFFECTIVE15,251 reports
PAIN14,708 reports
FATIGUE14,010 reports
NAUSEA13,039 reports
HEADACHE11,740 reports
ARTHRALGIA10,589 reports
DYSPNOEA10,202 reports
VOMITING9,638 reports
DIARRHOEA9,366 reports
RASH8,756 reports
OFF LABEL USE8,093 reports
DIZZINESS7,904 reports
PYREXIA7,681 reports
PRURITUS7,656 reports
ACUTE KIDNEY INJURY6,465 reports
DRUG HYPERSENSITIVITY6,401 reports
ASTHENIA6,216 reports
JOINT SWELLING6,101 reports
ANXIETY5,957 reports
CONDITION AGGRAVATED5,804 reports
PAIN IN EXTREMITY5,764 reports
MALAISE5,719 reports
ABDOMINAL PAIN UPPER5,704 reports
HYPERSENSITIVITY5,694 reports
PERIPHERAL SWELLING5,539 reports
NASOPHARYNGITIS5,527 reports
ABDOMINAL DISCOMFORT5,403 reports
INSOMNIA5,326 reports
URTICARIA5,172 reports
BACK PAIN5,166 reports
WEIGHT INCREASED5,146 reports
ABDOMINAL PAIN4,932 reports
SINUSITIS4,836 reports
DEPRESSION4,816 reports
CONFUSIONAL STATE4,765 reports
ALOPECIA4,707 reports
SWELLING4,513 reports
CHRONIC KIDNEY DISEASE4,442 reports
INFECTION4,441 reports
TOXICITY TO VARIOUS AGENTS4,423 reports
FALL4,395 reports
RHEUMATOID ARTHRITIS4,344 reports
DECREASED APPETITE4,166 reports
WEIGHT DECREASED4,133 reports
HYPERTENSION4,057 reports
PNEUMONIA4,057 reports
GENERAL PHYSICAL HEALTH DETERIORATION3,961 reports
CHEST PAIN3,920 reports
COUGH3,905 reports
MUSCULOSKELETAL STIFFNESS3,835 reports
LOWER RESPIRATORY TRACT INFECTION3,818 reports
BLISTER3,775 reports
GAIT DISTURBANCE3,741 reports
GASTROINTESTINAL DISORDER3,703 reports
DRUG INTOLERANCE3,683 reports
ARTHROPATHY3,676 reports
HYPOAESTHESIA3,631 reports
DISCOMFORT3,579 reports
RENAL FAILURE3,547 reports
SOMNOLENCE3,515 reports
STOMATITIS3,471 reports
HEPATIC ENZYME INCREASED3,464 reports
PRODUCT USE IN UNAPPROVED INDICATION3,397 reports
INTENTIONAL OVERDOSE3,378 reports
INJURY3,365 reports
PARAESTHESIA3,353 reports
CONTUSION3,347 reports
INFUSION RELATED REACTION3,303 reports
OVERDOSE3,234 reports
MUSCLE SPASMS3,211 reports
IMPAIRED HEALING3,163 reports
FEELING ABNORMAL3,085 reports
CONSTIPATION3,068 reports
IRRITABLE BOWEL SYNDROME3,053 reports
DEATH3,032 reports
SYNOVITIS2,990 reports
PERICARDITIS2,986 reports
DRUG INTERACTION2,958 reports
HYPOTENSION2,914 reports
COMPLETED SUICIDE2,854 reports
SYSTEMIC LUPUS ERYTHEMATOSUS2,849 reports
THERAPEUTIC PRODUCT EFFECT DECREASED2,846 reports
PRODUCT USE ISSUE2,842 reports
MUSCLE INJURY2,824 reports
DUODENAL ULCER PERFORATION2,763 reports
FOLLICULITIS2,756 reports
CONTRAINDICATED PRODUCT ADMINISTERED2,749 reports
SUICIDE ATTEMPT2,744 reports
PEMPHIGUS2,718 reports
GLOSSODYNIA2,715 reports
ANAEMIA2,714 reports
ANGIOEDEMA2,698 reports
WOUND2,689 reports
ERYTHEMA2,665 reports
HAND DEFORMITY2,644 reports
HELICOBACTER INFECTION2,643 reports
MIGRAINE2,615 reports
MATERNAL EXPOSURE DURING PREGNANCY2,604 reports
SLEEP DISORDER2,546 reports
PSORIATIC ARTHROPATHY2,545 reports

Key Safety Signals

  • Acute kidney injury and drug hypersensitivity are key safety signals, indicating potential severe adverse reactions.
  • A significant number of reports involve falls and respiratory tract infections, highlighting potential risks in elderly patients.
  • There are multiple reports of serious conditions like pneumonia and chronic kidney disease, suggesting a need for caution.

Patient Demographics

Adverse event reports by sex: Female: 111,952, Male: 61,281, Unknown: 601. The most frequently reported age groups are age 44 (3,366 reports), age 43 (2,928 reports), age 59 (2,646 reports). These demographics reflect reporting patterns and may not represent the full patient population.

Report Outcomes

Out of 191,770 classified reports for IBUPROFEN CAPSULES 200 MG:

  • Serious: 139,850 reports (72.9%) — includes hospitalization, disability, life-threatening events, or death
  • Non-Serious: 51,920 reports (27.1%)
Serious 72.9%Non-Serious 27.1%

The FDA classifies an adverse event as “serious” if it results in death, hospitalization, disability, congenital anomaly, or requires intervention to prevent permanent damage.

Demographics Breakdown

Reports by Sex

Female111,952 (64.4%)
Male61,281 (35.3%)
Unknown601 (0.3%)

Reports by Age

Age 443,366 reports
Age 432,928 reports
Age 592,646 reports
Age 572,527 reports
Age 542,522 reports
Age 502,519 reports
Age 582,519 reports
Age 612,511 reports
Age 532,509 reports
Age 552,475 reports
Age 602,473 reports
Age 622,444 reports
Age 632,414 reports
Age 522,364 reports
Age 562,361 reports
Age 492,325 reports
Age 512,277 reports
Age 422,265 reports
Age 482,198 reports
Age 652,190 reports

Demographics reflect voluntary FDA adverse event reporting patterns and may not represent the full patient population.

Drug Interactions & Warnings

Ibuprofen can interact with other medications, potentially increasing the risk of side effects. Patients should consult a healthcare provider before combining it with other drugs.

What You Should Know

If you are taking Ibuprofen Capsules 200 Mg, here are important things to know. The most commonly reported side effects include drug ineffective, pain, fatigue, nausea, headache. While many of these may be mild and temporary, you should contact your healthcare provider if any symptoms are severe or persistent. Always follow the prescribed dosage and duration of use. Be aware of potential interactions with other medications and consult a healthcare provider if you have any concerns. If you experience a serious adverse reaction, seek emergency medical attention immediately or call 911. You can report side effects to the FDA's MedWatch program at 1-800-FDA-1088.

Regulatory Context

The FDA continues to monitor the safety of ibuprofen. Patients should report any severe or unusual side effects to their healthcare provider.

Frequently Asked Questions

How many adverse event reports has the FDA received for Ibuprofen Capsules 200 Mg?

The FDA has received approximately 482,848 adverse event reports associated with Ibuprofen Capsules 200 Mg. These reports come from healthcare professionals, consumers, and manufacturers through the FDA Adverse Event Reporting System (FAERS). Note that the number of reports does not directly indicate the frequency of side effects, as adverse events are voluntarily reported and may be underrepresented.

What are the most commonly reported side effects of Ibuprofen Capsules 200 Mg?

The most frequently reported adverse events for Ibuprofen Capsules 200 Mg include Drug Ineffective, Pain, Fatigue, Nausea, Headache. By volume, the top reported reactions are: Drug Ineffective (15,251 reports), Pain (14,708 reports), Fatigue (14,010 reports). These figures reflect FDA adverse event reports and may not represent the true incidence rate of these side effects in all patients taking Ibuprofen Capsules 200 Mg.

What percentage of Ibuprofen Capsules 200 Mg adverse event reports are serious?

Out of 191,770 classified reports, 139,850 (72.9%) were classified as serious and 51,920 as non-serious. The FDA classifies an event as "serious" if it results in death, hospitalization, disability, or other medically significant outcomes. A higher serious-event ratio warrants closer attention but does not necessarily mean the drug is unsafe.

Who reports adverse events for Ibuprofen Capsules 200 Mg (by sex)?

Adverse event reports for Ibuprofen Capsules 200 Mg break down by patient sex as follows: Female: 111,952, Male: 61,281, Unknown: 601. This distribution reflects reporting patterns rather than actual risk differences between groups. Reporting rates can be influenced by prescribing patterns, disease demographics, and reporting behavior.

What age groups report the most side effects for Ibuprofen Capsules 200 Mg?

The most frequently reported age groups for Ibuprofen Capsules 200 Mg adverse events are: age 44: 3,366 reports, age 43: 2,928 reports, age 59: 2,646 reports, age 57: 2,527 reports, age 54: 2,522 reports. Age-related reporting patterns can reflect both the demographics of the patient population and potential age-related susceptibility to certain side effects.

Who manufactures Ibuprofen Capsules 200 Mg?

The primary manufacturer associated with Ibuprofen Capsules 200 Mg adverse event reports is Hart Health. Multiple manufacturers may produce generic versions of this drug. The manufacturer listed reflects the most frequently reported brand in FDA adverse event data.

What other side effects have been reported for Ibuprofen Capsules 200 Mg?

Beyond the most common reactions, other reported adverse events for Ibuprofen Capsules 200 Mg include: Arthralgia, Dyspnoea, Vomiting, Diarrhoea, Rash. Less common side effects can still be clinically significant. Patients should report any unusual symptoms to their healthcare provider.

How do I report a side effect from Ibuprofen Capsules 200 Mg?

You can report adverse events from Ibuprofen Capsules 200 Mg to the FDA through their MedWatch program at www.fda.gov/medwatch, by calling 1-800-FDA-1088, or by completing Form FDA 3500. Healthcare professionals, consumers, and manufacturers can all submit reports. Reporting helps the FDA monitor drug safety after approval.

What is Ibuprofen Capsules 200 Mg's safety score and what does it mean?

Ibuprofen Capsules 200 Mg has a safety concern score of 65 out of 100 (elevated concern). This score is calculated from the ratio of serious to non-serious adverse events, the diversity of reported reactions, and the overall volume of reports relative to usage. The most common reactions include pain, fatigue, and nausea, indicating a broad range of mild to moderate side effects.

What are the key safety signals for Ibuprofen Capsules 200 Mg?

Key safety signals identified in Ibuprofen Capsules 200 Mg's adverse event data include: Acute kidney injury and drug hypersensitivity are key safety signals, indicating potential severe adverse reactions.. A significant number of reports involve falls and respiratory tract infections, highlighting potential risks in elderly patients.. There are multiple reports of serious conditions like pneumonia and chronic kidney disease, suggesting a need for caution.. These signals are derived from patterns in FDA reports and should be discussed with a healthcare provider for personalized assessment.

Does Ibuprofen Capsules 200 Mg interact with other drugs?

Ibuprofen can interact with other medications, potentially increasing the risk of side effects. Patients should consult a healthcare provider before combining it with other drugs. Always inform your healthcare provider about all medications, supplements, and over-the-counter drugs you are taking before starting Ibuprofen Capsules 200 Mg.

What should patients know before taking Ibuprofen Capsules 200 Mg?

Always follow the prescribed dosage and duration of use. Be aware of potential interactions with other medications and consult a healthcare provider if you have any concerns.

Are Ibuprofen Capsules 200 Mg side effects well-documented?

Ibuprofen Capsules 200 Mg has 482,848 adverse event reports on file with the FDA. Serious reactions such as acute kidney injury and drug hypersensitivity are reported, but less frequently. The volume of reports for Ibuprofen Capsules 200 Mg reflects both the drug's usage level and the vigilance of the reporting community.

What is the FDA's position on Ibuprofen Capsules 200 Mg?

The FDA continues to monitor the safety of ibuprofen. Patients should report any severe or unusual side effects to their healthcare provider. For the most current regulatory information, check the FDA's drug labeling database or consult your pharmacist.

Related Drugs

Drugs related to IBUPROFEN CAPSULES 200 MG based on therapeutic use, drug class, or shared indications:

AcetaminophenAspirinCorticosteroidsAnticoagulantsDiuretics
Important Disclaimer: This content is generated by AI analysis of FDA adverse event reports and is provided for informational purposes only. It is not medical advice. Adverse event reports submitted to the FDA do not prove that a medication caused the reported side effect. Always consult your healthcare provider before starting, stopping, or changing any medication. If you experience a serious side effect, contact your doctor or call 911 immediately.