IBUPROFEN TABLET, FILM COATED

25/100 · Low Risk

Manufactured by -Sun Pharmaceutical Industries, Inc.

Ibuprofen Film-Coated Tablets: Common Mild Reactions with Few Serious Events

482,730 FDA adverse event reports analyzed

Last updated: 2026-05-12

About IBUPROFEN TABLET, FILM COATED

IBUPROFEN TABLET, FILM COATED is a medication tracked in the FDA Adverse Event Reporting System (FAERS), manufactured by -Sun Pharmaceutical Industries, Inc.. Based on analysis of 482,730 FDA adverse event reports, IBUPROFEN TABLET, FILM COATED has a safety score of 25 out of 100. This lower score reflects a significant number of adverse event reports, suggesting that patients should discuss potential risks carefully with their healthcare provider. The most commonly reported adverse reactions for IBUPROFEN TABLET, FILM COATED include DRUG INEFFECTIVE, PAIN, FATIGUE, NAUSEA, HEADACHE. This page provides a comprehensive breakdown of reported side effects, safety signals, patient demographics, and AI-powered safety analysis for IBUPROFEN TABLET, FILM COATED.

AI Safety Analysis

Ibuprofen Tablet, Film Coated has a safety concern score of 25 out of 100, placing it in the low concern category based on analysis of FDA adverse event data. The FDA has received approximately 482,730 adverse event reports for this medication, which is primarily manufactured by -Sun Pharmaceutical Industries, Inc..

The most commonly reported adverse events include Drug Ineffective, Pain, Fatigue. Of classified reports, 73.0% were designated as serious by the FDA, meaning they involved hospitalization, disability, or other significant medical outcomes. Most reported reactions are mild and include pain, fatigue, and nausea.

Serious adverse events, such as acute kidney injury and falls, are less common but still reported. The majority of reactions are not life-threatening, with a serious event rate of 73%. Reported reactions are diverse, with over 100 distinct reactions recorded.

Patients taking Ibuprofen Tablet, Film Coated should monitor for the commonly reported side effects and contact their healthcare provider if they experience any unusual symptoms. Ibuprofen can interact with other NSAIDs and anticoagulants, potentially increasing the risk of gastrointestinal bleeding and renal impairment. Patients should avoid these combinations unless advised by a healthcare provider. This analysis is based on voluntary FDA adverse event reports and should not replace professional medical advice.

Safety Score: 25/100

Ibuprofen Tablet, Film Coated received a safety concern score of 25/100 (low concern). This is based on a 73.0% serious event ratio across 191,661 classified reports. The score accounts for 482,730 total adverse event reports and 100 distinct reaction types. This relatively low score suggests a favorable safety profile in reported data.

Top Adverse Reactions

DRUG INEFFECTIVE15,237 reports
PAIN14,705 reports
FATIGUE14,005 reports
NAUSEA13,030 reports
HEADACHE11,736 reports
ARTHRALGIA10,589 reports
DYSPNOEA10,201 reports
VOMITING9,634 reports
DIARRHOEA9,361 reports
RASH8,753 reports
OFF LABEL USE8,093 reports
DIZZINESS7,898 reports
PYREXIA7,681 reports
PRURITUS7,652 reports
ACUTE KIDNEY INJURY6,465 reports
DRUG HYPERSENSITIVITY6,401 reports
ASTHENIA6,216 reports
JOINT SWELLING6,100 reports
ANXIETY5,956 reports
CONDITION AGGRAVATED5,802 reports
PAIN IN EXTREMITY5,763 reports
MALAISE5,714 reports
ABDOMINAL PAIN UPPER5,692 reports
HYPERSENSITIVITY5,687 reports
PERIPHERAL SWELLING5,539 reports
NASOPHARYNGITIS5,527 reports
ABDOMINAL DISCOMFORT5,397 reports
INSOMNIA5,326 reports
BACK PAIN5,166 reports
URTICARIA5,166 reports
WEIGHT INCREASED5,146 reports
ABDOMINAL PAIN4,931 reports
SINUSITIS4,836 reports
DEPRESSION4,816 reports
CONFUSIONAL STATE4,765 reports
ALOPECIA4,706 reports
SWELLING4,512 reports
CHRONIC KIDNEY DISEASE4,442 reports
INFECTION4,441 reports
TOXICITY TO VARIOUS AGENTS4,423 reports
FALL4,395 reports
RHEUMATOID ARTHRITIS4,344 reports
DECREASED APPETITE4,166 reports
WEIGHT DECREASED4,133 reports
HYPERTENSION4,057 reports
PNEUMONIA4,057 reports
GENERAL PHYSICAL HEALTH DETERIORATION3,961 reports
CHEST PAIN3,920 reports
COUGH3,905 reports
MUSCULOSKELETAL STIFFNESS3,835 reports
LOWER RESPIRATORY TRACT INFECTION3,818 reports
BLISTER3,775 reports
GAIT DISTURBANCE3,740 reports
GASTROINTESTINAL DISORDER3,703 reports
DRUG INTOLERANCE3,683 reports
ARTHROPATHY3,676 reports
HYPOAESTHESIA3,630 reports
DISCOMFORT3,579 reports
RENAL FAILURE3,547 reports
SOMNOLENCE3,509 reports
STOMATITIS3,471 reports
HEPATIC ENZYME INCREASED3,464 reports
PRODUCT USE IN UNAPPROVED INDICATION3,397 reports
INTENTIONAL OVERDOSE3,378 reports
INJURY3,365 reports
PARAESTHESIA3,352 reports
CONTUSION3,347 reports
INFUSION RELATED REACTION3,303 reports
OVERDOSE3,234 reports
MUSCLE SPASMS3,211 reports
IMPAIRED HEALING3,163 reports
FEELING ABNORMAL3,083 reports
CONSTIPATION3,068 reports
IRRITABLE BOWEL SYNDROME3,053 reports
DEATH3,032 reports
SYNOVITIS2,990 reports
PERICARDITIS2,986 reports
DRUG INTERACTION2,958 reports
HYPOTENSION2,914 reports
COMPLETED SUICIDE2,854 reports
SYSTEMIC LUPUS ERYTHEMATOSUS2,849 reports
THERAPEUTIC PRODUCT EFFECT DECREASED2,846 reports
PRODUCT USE ISSUE2,842 reports
MUSCLE INJURY2,824 reports
DUODENAL ULCER PERFORATION2,763 reports
FOLLICULITIS2,756 reports
CONTRAINDICATED PRODUCT ADMINISTERED2,749 reports
SUICIDE ATTEMPT2,744 reports
PEMPHIGUS2,718 reports
ANAEMIA2,714 reports
GLOSSODYNIA2,712 reports
ANGIOEDEMA2,698 reports
WOUND2,689 reports
ERYTHEMA2,664 reports
HAND DEFORMITY2,644 reports
HELICOBACTER INFECTION2,643 reports
MIGRAINE2,614 reports
MATERNAL EXPOSURE DURING PREGNANCY2,604 reports
SLEEP DISORDER2,546 reports
PSORIATIC ARTHROPATHY2,545 reports

Key Safety Signals

  • Acute kidney injury and falls are key safety signals, indicating potential renal and musculoskeletal risks.
  • Drug hypersensitivity and rash are also notable, suggesting potential allergic reactions.
  • Serious adverse events like pneumonia and chronic kidney disease are reported but less frequently.

Patient Demographics

Adverse event reports by sex: Female: 111,882, Male: 61,245, Unknown: 600. The most frequently reported age groups are age 44 (3,366 reports), age 43 (2,928 reports), age 59 (2,643 reports). These demographics reflect reporting patterns and may not represent the full patient population.

Report Outcomes

Out of 191,661 classified reports for IBUPROFEN TABLET, FILM COATED:

  • Serious: 139,842 reports (73.0%) — includes hospitalization, disability, life-threatening events, or death
  • Non-Serious: 51,819 reports (27.0%)
Serious 73.0%Non-Serious 27.0%

The FDA classifies an adverse event as “serious” if it results in death, hospitalization, disability, congenital anomaly, or requires intervention to prevent permanent damage.

Demographics Breakdown

Reports by Sex

Female111,882 (64.4%)
Male61,245 (35.3%)
Unknown600 (0.3%)

Reports by Age

Age 443,366 reports
Age 432,928 reports
Age 592,643 reports
Age 572,526 reports
Age 542,520 reports
Age 582,517 reports
Age 502,515 reports
Age 612,509 reports
Age 532,506 reports
Age 602,473 reports
Age 552,471 reports
Age 622,442 reports
Age 632,412 reports
Age 522,364 reports
Age 562,359 reports
Age 492,325 reports
Age 512,277 reports
Age 422,263 reports
Age 482,196 reports
Age 652,189 reports

Demographics reflect voluntary FDA adverse event reporting patterns and may not represent the full patient population.

Drug Interactions & Warnings

Ibuprofen can interact with other NSAIDs and anticoagulants, potentially increasing the risk of gastrointestinal bleeding and renal impairment. Patients should avoid these combinations unless advised by a healthcare provider.

What You Should Know

If you are taking Ibuprofen Tablet, Film Coated, here are important things to know. The most commonly reported side effects include drug ineffective, pain, fatigue, nausea, headache. While many of these may be mild and temporary, you should contact your healthcare provider if any symptoms are severe or persistent. Take ibuprofen as directed to minimize the risk of side effects. Be aware of potential interactions with other medications and inform your healthcare provider of all drugs you are taking. If you experience a serious adverse reaction, seek emergency medical attention immediately or call 911. You can report side effects to the FDA's MedWatch program at 1-800-FDA-1088.

Regulatory Context

The FDA continues to monitor the safety of ibuprofen and has not issued any specific warnings or recalls for this formulation. However, patients should report any severe or unusual reactions to their healthcare provider.

Frequently Asked Questions

How many adverse event reports has the FDA received for Ibuprofen Tablet, Film Coated?

The FDA has received approximately 482,730 adverse event reports associated with Ibuprofen Tablet, Film Coated. These reports come from healthcare professionals, consumers, and manufacturers through the FDA Adverse Event Reporting System (FAERS). Note that the number of reports does not directly indicate the frequency of side effects, as adverse events are voluntarily reported and may be underrepresented.

What are the most commonly reported side effects of Ibuprofen Tablet, Film Coated?

The most frequently reported adverse events for Ibuprofen Tablet, Film Coated include Drug Ineffective, Pain, Fatigue, Nausea, Headache. By volume, the top reported reactions are: Drug Ineffective (15,237 reports), Pain (14,705 reports), Fatigue (14,005 reports). These figures reflect FDA adverse event reports and may not represent the true incidence rate of these side effects in all patients taking Ibuprofen Tablet, Film Coated.

What percentage of Ibuprofen Tablet, Film Coated adverse event reports are serious?

Out of 191,661 classified reports, 139,842 (73.0%) were classified as serious and 51,819 as non-serious. The FDA classifies an event as "serious" if it results in death, hospitalization, disability, or other medically significant outcomes. A higher serious-event ratio warrants closer attention but does not necessarily mean the drug is unsafe.

Who reports adverse events for Ibuprofen Tablet, Film Coated (by sex)?

Adverse event reports for Ibuprofen Tablet, Film Coated break down by patient sex as follows: Female: 111,882, Male: 61,245, Unknown: 600. This distribution reflects reporting patterns rather than actual risk differences between groups. Reporting rates can be influenced by prescribing patterns, disease demographics, and reporting behavior.

What age groups report the most side effects for Ibuprofen Tablet, Film Coated?

The most frequently reported age groups for Ibuprofen Tablet, Film Coated adverse events are: age 44: 3,366 reports, age 43: 2,928 reports, age 59: 2,643 reports, age 57: 2,526 reports, age 54: 2,520 reports. Age-related reporting patterns can reflect both the demographics of the patient population and potential age-related susceptibility to certain side effects.

Who manufactures Ibuprofen Tablet, Film Coated?

The primary manufacturer associated with Ibuprofen Tablet, Film Coated adverse event reports is -Sun Pharmaceutical Industries, Inc.. Multiple manufacturers may produce generic versions of this drug. The manufacturer listed reflects the most frequently reported brand in FDA adverse event data.

What other side effects have been reported for Ibuprofen Tablet, Film Coated?

Beyond the most common reactions, other reported adverse events for Ibuprofen Tablet, Film Coated include: Arthralgia, Dyspnoea, Vomiting, Diarrhoea, Rash. Less common side effects can still be clinically significant. Patients should report any unusual symptoms to their healthcare provider.

How do I report a side effect from Ibuprofen Tablet, Film Coated?

You can report adverse events from Ibuprofen Tablet, Film Coated to the FDA through their MedWatch program at www.fda.gov/medwatch, by calling 1-800-FDA-1088, or by completing Form FDA 3500. Healthcare professionals, consumers, and manufacturers can all submit reports. Reporting helps the FDA monitor drug safety after approval.

What is Ibuprofen Tablet, Film Coated's safety score and what does it mean?

Ibuprofen Tablet, Film Coated has a safety concern score of 25 out of 100 (low concern). This score is calculated from the ratio of serious to non-serious adverse events, the diversity of reported reactions, and the overall volume of reports relative to usage. Most reported reactions are mild and include pain, fatigue, and nausea.

What are the key safety signals for Ibuprofen Tablet, Film Coated?

Key safety signals identified in Ibuprofen Tablet, Film Coated's adverse event data include: Acute kidney injury and falls are key safety signals, indicating potential renal and musculoskeletal risks.. Drug hypersensitivity and rash are also notable, suggesting potential allergic reactions.. Serious adverse events like pneumonia and chronic kidney disease are reported but less frequently.. These signals are derived from patterns in FDA reports and should be discussed with a healthcare provider for personalized assessment.

Does Ibuprofen Tablet, Film Coated interact with other drugs?

Ibuprofen can interact with other NSAIDs and anticoagulants, potentially increasing the risk of gastrointestinal bleeding and renal impairment. Patients should avoid these combinations unless advised by a healthcare provider. Always inform your healthcare provider about all medications, supplements, and over-the-counter drugs you are taking before starting Ibuprofen Tablet, Film Coated.

What should patients know before taking Ibuprofen Tablet, Film Coated?

Take ibuprofen as directed to minimize the risk of side effects. Be aware of potential interactions with other medications and inform your healthcare provider of all drugs you are taking.

Are Ibuprofen Tablet, Film Coated side effects well-documented?

Ibuprofen Tablet, Film Coated has 482,730 adverse event reports on file with the FDA. Serious adverse events, such as acute kidney injury and falls, are less common but still reported. The volume of reports for Ibuprofen Tablet, Film Coated reflects both the drug's usage level and the vigilance of the reporting community.

What is the FDA's position on Ibuprofen Tablet, Film Coated?

The FDA continues to monitor the safety of ibuprofen and has not issued any specific warnings or recalls for this formulation. However, patients should report any severe or unusual reactions to their healthcare provider. For the most current regulatory information, check the FDA's drug labeling database or consult your pharmacist.

Related Drugs

Drugs related to IBUPROFEN TABLET, FILM COATED based on therapeutic use, drug class, or shared indications:

AcetaminophenAspirinWarfarin
Important Disclaimer: This content is generated by AI analysis of FDA adverse event reports and is provided for informational purposes only. It is not medical advice. Adverse event reports submitted to the FDA do not prove that a medication caused the reported side effect. Always consult your healthcare provider before starting, stopping, or changing any medication. If you experience a serious side effect, contact your doctor or call 911 immediately.