ISOPROPYL ALCOHOL

85/100 · Critical

Manufactured by Target Corporation

Isopropyl Alcohol Adverse Events: High Seriousness and Diverse Reactions

144,811 FDA adverse event reports analyzed

Last updated: 2026-05-12

About ISOPROPYL ALCOHOL

ISOPROPYL ALCOHOL is a medication tracked in the FDA Adverse Event Reporting System (FAERS), manufactured by Target Corporation. Based on analysis of 144,811 FDA adverse event reports, ISOPROPYL ALCOHOL has a safety score of 85 out of 100. This score indicates a relatively favorable safety profile, with fewer or less severe adverse events compared to many other tracked medications. The most commonly reported adverse reactions for ISOPROPYL ALCOHOL include TOXICITY TO VARIOUS AGENTS, COMPLETED SUICIDE, DRUG ABUSE, OVERDOSE, CONFUSIONAL STATE. This page provides a comprehensive breakdown of reported side effects, safety signals, patient demographics, and AI-powered safety analysis for ISOPROPYL ALCOHOL.

AI Safety Analysis

Isopropyl Alcohol has a safety concern score of 85 out of 100, placing it in the high concern category based on analysis of FDA adverse event data. The FDA has received approximately 144,811 adverse event reports for this medication, which is primarily manufactured by Target Corporation.

The most commonly reported adverse events include Toxicity To Various Agents, Completed Suicide, Drug Abuse. Of classified reports, 93.6% were designated as serious by the FDA, meaning they involved hospitalization, disability, or other significant medical outcomes. The majority of adverse events are serious, with over 93% of reports being serious.

A wide range of reactions are reported, indicating diverse safety concerns. Overdose and suicide attempts are among the most frequent adverse events. Sex distribution is nearly equal, with a slight majority of reports from females. The highest number of reports is from individuals aged 40-49.

Patients taking Isopropyl Alcohol should monitor for the commonly reported side effects and contact their healthcare provider if they experience any unusual symptoms. Isopropyl alcohol can cause toxicity and is associated with serious adverse events such as overdose and suicide attempts. It should be used with caution, especially in individuals with a history of drug abuse or mental health issues. This analysis is based on voluntary FDA adverse event reports and should not replace professional medical advice.

Safety Score: 85/100

Isopropyl Alcohol received a safety concern score of 85/100 (high concern). This is based on a 93.6% serious event ratio across 32,076 classified reports. The score accounts for 144,811 total adverse event reports and 100 distinct reaction types. This high score reflects a significant proportion of serious adverse events in the reporting data.

Top Adverse Reactions

TOXICITY TO VARIOUS AGENTS5,640 reports
COMPLETED SUICIDE5,182 reports
DRUG ABUSE5,094 reports
OVERDOSE2,000 reports
CONFUSIONAL STATE1,891 reports
FATIGUE1,887 reports
VOMITING1,882 reports
NAUSEA1,878 reports
PAIN1,845 reports
DEATH1,735 reports
DYSPNOEA1,690 reports
RASH1,680 reports
JOINT SWELLING1,583 reports
HYPERSENSITIVITY1,573 reports
HEPATIC ENZYME INCREASED1,570 reports
GLOSSODYNIA1,561 reports
PEMPHIGUS1,560 reports
DRUG INEFFECTIVE1,554 reports
OFF LABEL USE1,546 reports
INFUSION RELATED REACTION1,538 reports
IMPAIRED HEALING1,535 reports
INJURY1,531 reports
HAND DEFORMITY1,530 reports
IRRITABLE BOWEL SYNDROME1,528 reports
SYSTEMIC LUPUS ERYTHEMATOSUS1,524 reports
PERICARDITIS1,521 reports
HELICOBACTER INFECTION1,520 reports
INTENTIONAL OVERDOSE1,515 reports
WOUND1,511 reports
FOLLICULITIS1,501 reports
HEADACHE1,494 reports
WEIGHT INCREASED1,486 reports
HYPERTENSION1,484 reports
ARTHRALGIA1,469 reports
SWELLING1,464 reports
INSOMNIA1,451 reports
RHEUMATOID ARTHRITIS1,451 reports
CONDITION AGGRAVATED1,447 reports
SYNOVITIS1,445 reports
ALOPECIA1,428 reports
NASOPHARYNGITIS1,413 reports
ABDOMINAL DISCOMFORT1,404 reports
DUODENAL ULCER PERFORATION1,400 reports
GENERAL PHYSICAL HEALTH DETERIORATION1,392 reports
ILL DEFINED DISORDER1,378 reports
PYREXIA1,372 reports
SLEEP DISORDER1,361 reports
BLISTER1,353 reports
INFECTION1,353 reports
PRURITUS1,353 reports
TYPE 2 DIABETES MELLITUS1,332 reports
ARTHROPATHY1,326 reports
MUSCLE INJURY1,318 reports
STOMATITIS1,315 reports
DIZZINESS1,307 reports
SUICIDE ATTEMPT1,306 reports
DIARRHOEA1,304 reports
CARDIO RESPIRATORY ARREST1,293 reports
LOWER RESPIRATORY TRACT INFECTION1,286 reports
ANTI CYCLIC CITRULLINATED PEPTIDE ANTIBODY POSITIVE1,275 reports
PERIPHERAL SWELLING1,267 reports
PSORIATIC ARTHROPATHY1,259 reports
DISCOMFORT1,253 reports
DEPRESSION1,223 reports
URTICARIA1,220 reports
HYPOAESTHESIA1,208 reports
MALAISE1,200 reports
FIBROMYALGIA1,197 reports
SINUSITIS1,196 reports
CONTUSION1,186 reports
LIVER INJURY1,177 reports
RHEUMATIC FEVER1,155 reports
GASTROINTESTINAL DISORDER1,148 reports
MOBILITY DECREASED1,146 reports
INTENTIONAL PRODUCT USE ISSUE1,126 reports
WHEEZING1,116 reports
BLOOD CHOLESTEROL INCREASED1,112 reports
DRUG HYPERSENSITIVITY1,092 reports
PNEUMONIA1,092 reports
MUSCULOSKELETAL STIFFNESS1,081 reports
ANXIETY1,079 reports
ROAD TRAFFIC ACCIDENT1,071 reports
ABDOMINAL PAIN UPPER1,062 reports
CONTRAINDICATED PRODUCT ADMINISTERED1,060 reports
JOINT RANGE OF MOTION DECREASED1,059 reports
PAIN IN EXTREMITY1,045 reports
DRUG INTOLERANCE1,039 reports
RHEUMATOID FACTOR POSITIVE1,007 reports
DECREASED APPETITE991 reports
CHEST PAIN985 reports
MATERNAL EXPOSURE DURING PREGNANCY985 reports
MEMORY IMPAIRMENT967 reports
OEDEMA945 reports
ASTHENIA940 reports
SOMNOLENCE939 reports
DRUG INTERACTION930 reports
WEIGHT DECREASED929 reports
DYSPEPSIA922 reports
SLEEP DISORDER DUE TO GENERAL MEDICAL CONDITION, INSOMNIA TYPE919 reports
AMNESIA918 reports

Key Safety Signals

  • TOXICITY TO VARIOUS AGENTS and COMPLETED SUICIDE are the most frequent serious reactions.
  • DRUG ABUSE and OVERDOSE are significant safety signals.
  • FATIGUE and VOMITING are common, but less serious, reactions.

Patient Demographics

Adverse event reports by sex: Female: 15,016, Male: 14,387, Unknown: 54. The most frequently reported age groups are age 44 (1,610 reports), age 40 (1,032 reports), age 43 (885 reports). These demographics reflect reporting patterns and may not represent the full patient population.

Report Outcomes

Out of 32,076 classified reports for ISOPROPYL ALCOHOL:

  • Serious: 30,008 reports (93.6%) — includes hospitalization, disability, life-threatening events, or death
  • Non-Serious: 2,068 reports (6.4%)
Serious 93.6%Non-Serious 6.4%

The FDA classifies an adverse event as “serious” if it results in death, hospitalization, disability, congenital anomaly, or requires intervention to prevent permanent damage.

Demographics Breakdown

Reports by Sex

Female15,016 (51.0%)
Male14,387 (48.8%)
Unknown54 (0.2%)

Reports by Age

Age 441,610 reports
Age 401,032 reports
Age 43885 reports
Age 39557 reports
Age 36524 reports
Age 53515 reports
Age 46513 reports
Age 35512 reports
Age 50505 reports
Age 41498 reports
Age 45489 reports
Age 48488 reports
Age 49486 reports
Age 30477 reports
Age 29473 reports
Age 32473 reports
Age 38473 reports
Age 34470 reports
Age 37470 reports
Age 54460 reports

Demographics reflect voluntary FDA adverse event reporting patterns and may not represent the full patient population.

Drug Interactions & Warnings

Isopropyl alcohol can cause toxicity and is associated with serious adverse events such as overdose and suicide attempts. It should be used with caution, especially in individuals with a history of drug abuse or mental health issues.

What You Should Know

If you are taking Isopropyl Alcohol, here are important things to know. The most commonly reported side effects include toxicity to various agents, completed suicide, drug abuse, overdose, confusional state. While many of these may be mild and temporary, you should contact your healthcare provider if any symptoms are severe or persistent. Avoid using isopropyl alcohol in large quantities or for prolonged periods, as it can cause toxicity and serious adverse events. If you have a history of drug abuse or mental health issues, use isopropyl alcohol with caution and under medical supervision. If you experience a serious adverse reaction, seek emergency medical attention immediately or call 911. You can report side effects to the FDA's MedWatch program at 1-800-FDA-1088.

Regulatory Context

The FDA closely monitors isopropyl alcohol for safety concerns, particularly in over-the-counter products. Consumers should follow usage instructions and report any adverse events to the FDA.

Frequently Asked Questions

How many adverse event reports has the FDA received for Isopropyl Alcohol?

The FDA has received approximately 144,811 adverse event reports associated with Isopropyl Alcohol. These reports come from healthcare professionals, consumers, and manufacturers through the FDA Adverse Event Reporting System (FAERS). Note that the number of reports does not directly indicate the frequency of side effects, as adverse events are voluntarily reported and may be underrepresented.

What are the most commonly reported side effects of Isopropyl Alcohol?

The most frequently reported adverse events for Isopropyl Alcohol include Toxicity To Various Agents, Completed Suicide, Drug Abuse, Overdose, Confusional State. By volume, the top reported reactions are: Toxicity To Various Agents (5,640 reports), Completed Suicide (5,182 reports), Drug Abuse (5,094 reports). These figures reflect FDA adverse event reports and may not represent the true incidence rate of these side effects in all patients taking Isopropyl Alcohol.

What percentage of Isopropyl Alcohol adverse event reports are serious?

Out of 32,076 classified reports, 30,008 (93.6%) were classified as serious and 2,068 as non-serious. The FDA classifies an event as "serious" if it results in death, hospitalization, disability, or other medically significant outcomes. A higher serious-event ratio warrants closer attention but does not necessarily mean the drug is unsafe.

Who reports adverse events for Isopropyl Alcohol (by sex)?

Adverse event reports for Isopropyl Alcohol break down by patient sex as follows: Female: 15,016, Male: 14,387, Unknown: 54. This distribution reflects reporting patterns rather than actual risk differences between groups. Reporting rates can be influenced by prescribing patterns, disease demographics, and reporting behavior.

What age groups report the most side effects for Isopropyl Alcohol?

The most frequently reported age groups for Isopropyl Alcohol adverse events are: age 44: 1,610 reports, age 40: 1,032 reports, age 43: 885 reports, age 39: 557 reports, age 36: 524 reports. Age-related reporting patterns can reflect both the demographics of the patient population and potential age-related susceptibility to certain side effects.

Who manufactures Isopropyl Alcohol?

The primary manufacturer associated with Isopropyl Alcohol adverse event reports is Target Corporation. Multiple manufacturers may produce generic versions of this drug. The manufacturer listed reflects the most frequently reported brand in FDA adverse event data.

What other side effects have been reported for Isopropyl Alcohol?

Beyond the most common reactions, other reported adverse events for Isopropyl Alcohol include: Fatigue, Vomiting, Nausea, Pain, Death. Less common side effects can still be clinically significant. Patients should report any unusual symptoms to their healthcare provider.

How do I report a side effect from Isopropyl Alcohol?

You can report adverse events from Isopropyl Alcohol to the FDA through their MedWatch program at www.fda.gov/medwatch, by calling 1-800-FDA-1088, or by completing Form FDA 3500. Healthcare professionals, consumers, and manufacturers can all submit reports. Reporting helps the FDA monitor drug safety after approval.

What is Isopropyl Alcohol's safety score and what does it mean?

Isopropyl Alcohol has a safety concern score of 85 out of 100 (high concern). This score is calculated from the ratio of serious to non-serious adverse events, the diversity of reported reactions, and the overall volume of reports relative to usage. The majority of adverse events are serious, with over 93% of reports being serious.

What are the key safety signals for Isopropyl Alcohol?

Key safety signals identified in Isopropyl Alcohol's adverse event data include: TOXICITY TO VARIOUS AGENTS and COMPLETED SUICIDE are the most frequent serious reactions.. DRUG ABUSE and OVERDOSE are significant safety signals.. FATIGUE and VOMITING are common, but less serious, reactions.. These signals are derived from patterns in FDA reports and should be discussed with a healthcare provider for personalized assessment.

Does Isopropyl Alcohol interact with other drugs?

Isopropyl alcohol can cause toxicity and is associated with serious adverse events such as overdose and suicide attempts. It should be used with caution, especially in individuals with a history of drug abuse or mental health issues. Always inform your healthcare provider about all medications, supplements, and over-the-counter drugs you are taking before starting Isopropyl Alcohol.

What should patients know before taking Isopropyl Alcohol?

Avoid using isopropyl alcohol in large quantities or for prolonged periods, as it can cause toxicity and serious adverse events. If you have a history of drug abuse or mental health issues, use isopropyl alcohol with caution and under medical supervision.

Are Isopropyl Alcohol side effects well-documented?

Isopropyl Alcohol has 144,811 adverse event reports on file with the FDA. A wide range of reactions are reported, indicating diverse safety concerns. The volume of reports for Isopropyl Alcohol reflects both the drug's usage level and the vigilance of the reporting community.

What is the FDA's position on Isopropyl Alcohol?

The FDA closely monitors isopropyl alcohol for safety concerns, particularly in over-the-counter products. Consumers should follow usage instructions and report any adverse events to the FDA. For the most current regulatory information, check the FDA's drug labeling database or consult your pharmacist.

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Important Disclaimer: This content is generated by AI analysis of FDA adverse event reports and is provided for informational purposes only. It is not medical advice. Adverse event reports submitted to the FDA do not prove that a medication caused the reported side effect. Always consult your healthcare provider before starting, stopping, or changing any medication. If you experience a serious side effect, contact your doctor or call 911 immediately.