78/100 · Elevated
Manufactured by Korea Life Science
Magnesium Adverse Events: High Serious Reaction Rate
219,679 FDA adverse event reports analyzed
Last updated: 2026-05-12
MAGNESIUM is a medication tracked in the FDA Adverse Event Reporting System (FAERS), manufactured by Korea Life Science. Based on analysis of 219,679 FDA adverse event reports, MAGNESIUM has a safety score of 78 out of 100. This score indicates a relatively favorable safety profile, with fewer or less severe adverse events compared to many other tracked medications. The most commonly reported adverse reactions for MAGNESIUM include FATIGUE, NAUSEA, DIARRHOEA, HEADACHE, DRUG INEFFECTIVE. This page provides a comprehensive breakdown of reported side effects, safety signals, patient demographics, and AI-powered safety analysis for MAGNESIUM.
Magnesium has a safety concern score of 78 out of 100, placing it in the high concern category based on analysis of FDA adverse event data. The FDA has received approximately 219,679 adverse event reports for this medication, which is primarily manufactured by Korea Life Science.
The most commonly reported adverse events include Fatigue, Nausea, Diarrhoea. Of classified reports, 62.7% were designated as serious by the FDA, meaning they involved hospitalization, disability, or other significant medical outcomes. Fatigue and nausea are the most common adverse reactions.
Serious reactions, such as death and pneumonia, are reported frequently. A wide range of reactions, including neurological and gastrointestinal issues, are observed.
Patients taking Magnesium should monitor for the commonly reported side effects and contact their healthcare provider if they experience any unusual symptoms. Magnesium can cause various side effects, including fatigue, nausea, and dizziness. It is important to follow prescribed dosages and consult a healthcare provider if any adverse reactions occur. This analysis is based on voluntary FDA adverse event reports and should not replace professional medical advice.
Magnesium received a safety concern score of 78/100 (high concern). This is based on a 62.7% serious event ratio across 77,339 classified reports. The score accounts for 219,679 total adverse event reports and 100 distinct reaction types. This high score reflects a significant proportion of serious adverse events in the reporting data.
Adverse event reports by sex: Female: 50,710, Male: 21,325, Unknown: 45. The most frequently reported age groups are age 69 (1,481 reports), age 65 (1,433 reports), age 70 (1,433 reports). These demographics reflect reporting patterns and may not represent the full patient population.
Out of 77,339 classified reports for MAGNESIUM:
The FDA classifies an adverse event as “serious” if it results in death, hospitalization, disability, congenital anomaly, or requires intervention to prevent permanent damage.
Demographics reflect voluntary FDA adverse event reporting patterns and may not represent the full patient population.
Magnesium can cause various side effects, including fatigue, nausea, and dizziness. It is important to follow prescribed dosages and consult a healthcare provider if any adverse reactions occur.
If you are taking Magnesium, here are important things to know. The most commonly reported side effects include fatigue, nausea, diarrhoea, headache, drug ineffective. While many of these may be mild and temporary, you should contact your healthcare provider if any symptoms are severe or persistent. Monitor for signs of serious reactions such as difficulty breathing, chest pain, or severe allergic reactions. Follow prescribed dosages and consult a healthcare provider if any adverse reactions occur. If you experience a serious adverse reaction, seek emergency medical attention immediately or call 911. You can report side effects to the FDA's MedWatch program at 1-800-FDA-1088.
The FDA continues to monitor magnesium safety and has not issued any specific warnings or changes to labeling. However, patients should report any serious adverse events to their healthcare provider.
The FDA has received approximately 219,679 adverse event reports associated with Magnesium. These reports come from healthcare professionals, consumers, and manufacturers through the FDA Adverse Event Reporting System (FAERS). Note that the number of reports does not directly indicate the frequency of side effects, as adverse events are voluntarily reported and may be underrepresented.
The most frequently reported adverse events for Magnesium include Fatigue, Nausea, Diarrhoea, Headache, Drug Ineffective. By volume, the top reported reactions are: Fatigue (8,477 reports), Nausea (6,658 reports), Diarrhoea (6,465 reports). These figures reflect FDA adverse event reports and may not represent the true incidence rate of these side effects in all patients taking Magnesium.
Out of 77,339 classified reports, 48,502 (62.7%) were classified as serious and 28,837 as non-serious. The FDA classifies an event as "serious" if it results in death, hospitalization, disability, or other medically significant outcomes. A higher serious-event ratio warrants closer attention but does not necessarily mean the drug is unsafe.
Adverse event reports for Magnesium break down by patient sex as follows: Female: 50,710, Male: 21,325, Unknown: 45. This distribution reflects reporting patterns rather than actual risk differences between groups. Reporting rates can be influenced by prescribing patterns, disease demographics, and reporting behavior.
The most frequently reported age groups for Magnesium adverse events are: age 69: 1,481 reports, age 65: 1,433 reports, age 70: 1,433 reports, age 71: 1,401 reports, age 67: 1,368 reports. Age-related reporting patterns can reflect both the demographics of the patient population and potential age-related susceptibility to certain side effects.
The primary manufacturer associated with Magnesium adverse event reports is Korea Life Science. Multiple manufacturers may produce generic versions of this drug. The manufacturer listed reflects the most frequently reported brand in FDA adverse event data.
Beyond the most common reactions, other reported adverse events for Magnesium include: Pain, Off Label Use, Dizziness, Dyspnoea, Arthralgia. Less common side effects can still be clinically significant. Patients should report any unusual symptoms to their healthcare provider.
You can report adverse events from Magnesium to the FDA through their MedWatch program at www.fda.gov/medwatch, by calling 1-800-FDA-1088, or by completing Form FDA 3500. Healthcare professionals, consumers, and manufacturers can all submit reports. Reporting helps the FDA monitor drug safety after approval.
Magnesium has a safety concern score of 78 out of 100 (high concern). This score is calculated from the ratio of serious to non-serious adverse events, the diversity of reported reactions, and the overall volume of reports relative to usage. Fatigue and nausea are the most common adverse reactions.
Key safety signals identified in Magnesium's adverse event data include: High number of serious reactions (48,502 out of 77,339, 62.7%). Multiple serious conditions like pneumonia and death are reported. A diverse range of reactions, including neurological and gastrointestinal issues. These signals are derived from patterns in FDA reports and should be discussed with a healthcare provider for personalized assessment.
Magnesium can cause various side effects, including fatigue, nausea, and dizziness. It is important to follow prescribed dosages and consult a healthcare provider if any adverse reactions occur. Always inform your healthcare provider about all medications, supplements, and over-the-counter drugs you are taking before starting Magnesium.
Monitor for signs of serious reactions such as difficulty breathing, chest pain, or severe allergic reactions. Follow prescribed dosages and consult a healthcare provider if any adverse reactions occur.
Magnesium has 219,679 adverse event reports on file with the FDA. Serious reactions, such as death and pneumonia, are reported frequently. The volume of reports for Magnesium reflects both the drug's usage level and the vigilance of the reporting community.
The FDA continues to monitor magnesium safety and has not issued any specific warnings or changes to labeling. However, patients should report any serious adverse events to their healthcare provider. For the most current regulatory information, check the FDA's drug labeling database or consult your pharmacist.
The following drugs share commonly reported adverse reactions with MAGNESIUM:
Drugs related to MAGNESIUM based on therapeutic use, drug class, or shared indications: