OXYBUTYNIN CHLORIDE

65/100 · Elevated

Manufactured by Lannett Company, Inc.

Moderate Safety Concerns with Oxybutynin Chloride

19,830 FDA adverse event reports analyzed

Last updated: 2026-05-12

About OXYBUTYNIN CHLORIDE

OXYBUTYNIN CHLORIDE is a medication tracked in the FDA Adverse Event Reporting System (FAERS), manufactured by Lannett Company, Inc.. Based on analysis of 19,830 FDA adverse event reports, OXYBUTYNIN CHLORIDE has a safety score of 65 out of 100. This moderate score indicates a notable volume of adverse event reports that patients and providers should be aware of. The most commonly reported adverse reactions for OXYBUTYNIN CHLORIDE include FATIGUE, DRUG INEFFECTIVE, NAUSEA, FALL, HEADACHE. This page provides a comprehensive breakdown of reported side effects, safety signals, patient demographics, and AI-powered safety analysis for OXYBUTYNIN CHLORIDE.

AI Safety Analysis

Oxybutynin Chloride has a safety concern score of 65 out of 100, placing it in the elevated concern category based on analysis of FDA adverse event data. The FDA has received approximately 19,830 adverse event reports for this medication, which is primarily manufactured by Lannett Company, Inc..

The most commonly reported adverse events include Fatigue, Drug Ineffective, Nausea. Of classified reports, 56.5% were designated as serious by the FDA, meaning they involved hospitalization, disability, or other significant medical outcomes. Fatigue and dizziness are common, indicating potential cognitive and physical impacts.

Gastrointestinal issues like nausea, diarrhea, and constipation are frequent. Serious adverse events, including falls and pneumonia, are reported but less frequent. Drug interactions and dose omissions are noted, suggesting potential misuse or interaction risks.

Patients taking Oxybutynin Chloride should monitor for the commonly reported side effects and contact their healthcare provider if they experience any unusual symptoms. Oxybutynin Chloride can cause dizziness and fatigue, which may increase the risk of falls and accidents. Patients should avoid driving or operating heavy machinery until they know how the drug affects them. This analysis is based on voluntary FDA adverse event reports and should not replace professional medical advice.

Safety Score: 65/100

Oxybutynin Chloride received a safety concern score of 65/100 (elevated concern). This is based on a 56.5% serious event ratio across 8,392 classified reports. The score accounts for 19,830 total adverse event reports and 100 distinct reaction types. This elevated score indicates a notable proportion of serious adverse events and warrants careful monitoring.

Top Adverse Reactions

FATIGUE690 reports
DRUG INEFFECTIVE674 reports
NAUSEA571 reports
FALL569 reports
HEADACHE538 reports
DIARRHOEA489 reports
PAIN469 reports
URINARY TRACT INFECTION440 reports
DIZZINESS414 reports
CONSTIPATION397 reports
ASTHENIA381 reports
OFF LABEL USE359 reports
WEIGHT DECREASED356 reports
GAIT DISTURBANCE346 reports
PRODUCT DOSE OMISSION ISSUE321 reports
MALAISE318 reports
DYSPNOEA299 reports
PNEUMONIA269 reports
PYREXIA269 reports
VOMITING262 reports
DEATH260 reports
ARTHRALGIA254 reports
PRURITUS231 reports
COUGH224 reports
ABDOMINAL PAIN220 reports
BACK PAIN218 reports
ANAEMIA214 reports
DEPRESSION211 reports
PAIN IN EXTREMITY203 reports
INSOMNIA201 reports
BALANCE DISORDER199 reports
RASH197 reports
CONDITION AGGRAVATED192 reports
ANXIETY190 reports
FEELING ABNORMAL190 reports
DRY MOUTH189 reports
MULTIPLE SCLEROSIS RELAPSE186 reports
ERYTHEMA184 reports
DYSPEPSIA179 reports
CONFUSIONAL STATE178 reports
SOMNOLENCE177 reports
MEMORY IMPAIRMENT176 reports
HYPOAESTHESIA175 reports
COVID 19174 reports
DECREASED APPETITE173 reports
MUSCULAR WEAKNESS167 reports
MUSCLE SPASMS159 reports
MULTIPLE SCLEROSIS148 reports
PERIPHERAL SWELLING147 reports
PARAESTHESIA145 reports
ABDOMINAL PAIN UPPER141 reports
CHEST PAIN141 reports
HYPERTENSION141 reports
ABDOMINAL DISCOMFORT139 reports
FLUSHING137 reports
WEIGHT INCREASED134 reports
TREMOR129 reports
VISION BLURRED128 reports
DRUG INTERACTION127 reports
RECTAL HAEMORRHAGE127 reports
FREQUENT BOWEL MOVEMENTS126 reports
DEHYDRATION125 reports
NASOPHARYNGITIS125 reports
HAEMATOCHEZIA124 reports
INFUSION RELATED REACTION124 reports
COLITIS120 reports
HYPOTENSION119 reports
ORAL CANDIDIASIS119 reports
RADICULOPATHY119 reports
ALOPECIA118 reports
BLOOD PRESSURE INCREASED116 reports
COLITIS ULCERATIVE116 reports
VAGINAL DISCHARGE116 reports
CHRONIC SINUSITIS115 reports
FEMALE GENITAL TRACT FISTULA115 reports
PROCTITIS115 reports
VAGINAL FLATULENCE113 reports
CONTUSION111 reports
THERAPEUTIC PRODUCT EFFECT INCOMPLETE110 reports
ACUTE KIDNEY INJURY104 reports
DRUG HYPERSENSITIVITY104 reports
INFECTION104 reports
URINARY INCONTINENCE104 reports
CHRONIC KIDNEY DISEASE103 reports
DRUG DOSE OMISSION102 reports
SINUSITIS101 reports
HYPERSENSITIVITY99 reports
OEDEMA PERIPHERAL99 reports
MACULAR DEGENERATION98 reports
ILLNESS97 reports
PRODUCT USE IN UNAPPROVED INDICATION97 reports
INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION96 reports
INJECTION SITE PAIN96 reports
PROCEDURAL PAIN95 reports
THERAPY CESSATION94 reports
LOSS OF CONSCIOUSNESS93 reports
PARAESTHESIA ORAL93 reports
EYE PAIN92 reports
RENAL FAILURE89 reports
CEREBROVASCULAR ACCIDENT88 reports

Key Safety Signals

  • Frequent reports of falls and dizziness suggest a risk of falls and accidents.
  • Gastrointestinal issues are common, which could impact quality of life.
  • Serious adverse events like pneumonia and death are reported but less frequent.
  • Drug interactions and dose omissions are noted, indicating potential misuse or interaction risks.

Patient Demographics

Adverse event reports by sex: Female: 5,585, Male: 2,293, Unknown: 14. The most frequently reported age groups are age 71 (178 reports), age 65 (161 reports), age 62 (149 reports). These demographics reflect reporting patterns and may not represent the full patient population.

Report Outcomes

Out of 8,392 classified reports for OXYBUTYNIN CHLORIDE:

  • Serious: 4,742 reports (56.5%) — includes hospitalization, disability, life-threatening events, or death
  • Non-Serious: 3,650 reports (43.5%)
Serious 56.5%Non-Serious 43.5%

The FDA classifies an adverse event as “serious” if it results in death, hospitalization, disability, congenital anomaly, or requires intervention to prevent permanent damage.

Demographics Breakdown

Reports by Sex

Female5,585 (70.8%)
Male2,293 (29.1%)
Unknown14 (0.2%)

Reports by Age

Age 71178 reports
Age 65161 reports
Age 62149 reports
Age 69129 reports
Age 66127 reports
Age 68127 reports
Age 67123 reports
Age 75123 reports
Age 64121 reports
Age 70121 reports
Age 57112 reports
Age 60111 reports
Age 77111 reports
Age 78111 reports
Age 74110 reports
Age 63109 reports
Age 76109 reports
Age 61107 reports
Age 73107 reports
Age 56106 reports

Demographics reflect voluntary FDA adverse event reporting patterns and may not represent the full patient population.

Drug Interactions & Warnings

Oxybutynin Chloride can cause dizziness and fatigue, which may increase the risk of falls and accidents. Patients should avoid driving or operating heavy machinery until they know how the drug affects them.

What You Should Know

If you are taking Oxybutynin Chloride, here are important things to know. The most commonly reported side effects include fatigue, drug ineffective, nausea, fall, headache. While many of these may be mild and temporary, you should contact your healthcare provider if any symptoms are severe or persistent. Patients should report any unusual symptoms to their healthcare provider immediately. Avoid driving or operating heavy machinery if you experience dizziness or fatigue. If you experience a serious adverse reaction, seek emergency medical attention immediately or call 911. You can report side effects to the FDA's MedWatch program at 1-800-FDA-1088.

Regulatory Context

The FDA continues to monitor Oxybutynin Chloride for safety. Healthcare providers should be aware of the potential for serious adverse events and monitor patients closely.

Frequently Asked Questions

How many adverse event reports has the FDA received for Oxybutynin Chloride?

The FDA has received approximately 19,830 adverse event reports associated with Oxybutynin Chloride. These reports come from healthcare professionals, consumers, and manufacturers through the FDA Adverse Event Reporting System (FAERS). Note that the number of reports does not directly indicate the frequency of side effects, as adverse events are voluntarily reported and may be underrepresented.

What are the most commonly reported side effects of Oxybutynin Chloride?

The most frequently reported adverse events for Oxybutynin Chloride include Fatigue, Drug Ineffective, Nausea, Fall, Headache. By volume, the top reported reactions are: Fatigue (690 reports), Drug Ineffective (674 reports), Nausea (571 reports). These figures reflect FDA adverse event reports and may not represent the true incidence rate of these side effects in all patients taking Oxybutynin Chloride.

What percentage of Oxybutynin Chloride adverse event reports are serious?

Out of 8,392 classified reports, 4,742 (56.5%) were classified as serious and 3,650 as non-serious. The FDA classifies an event as "serious" if it results in death, hospitalization, disability, or other medically significant outcomes. A higher serious-event ratio warrants closer attention but does not necessarily mean the drug is unsafe.

Who reports adverse events for Oxybutynin Chloride (by sex)?

Adverse event reports for Oxybutynin Chloride break down by patient sex as follows: Female: 5,585, Male: 2,293, Unknown: 14. This distribution reflects reporting patterns rather than actual risk differences between groups. Reporting rates can be influenced by prescribing patterns, disease demographics, and reporting behavior.

What age groups report the most side effects for Oxybutynin Chloride?

The most frequently reported age groups for Oxybutynin Chloride adverse events are: age 71: 178 reports, age 65: 161 reports, age 62: 149 reports, age 69: 129 reports, age 66: 127 reports. Age-related reporting patterns can reflect both the demographics of the patient population and potential age-related susceptibility to certain side effects.

Who manufactures Oxybutynin Chloride?

The primary manufacturer associated with Oxybutynin Chloride adverse event reports is Lannett Company, Inc.. Multiple manufacturers may produce generic versions of this drug. The manufacturer listed reflects the most frequently reported brand in FDA adverse event data.

What other side effects have been reported for Oxybutynin Chloride?

Beyond the most common reactions, other reported adverse events for Oxybutynin Chloride include: Diarrhoea, Pain, Urinary Tract Infection, Dizziness, Constipation. Less common side effects can still be clinically significant. Patients should report any unusual symptoms to their healthcare provider.

How do I report a side effect from Oxybutynin Chloride?

You can report adverse events from Oxybutynin Chloride to the FDA through their MedWatch program at www.fda.gov/medwatch, by calling 1-800-FDA-1088, or by completing Form FDA 3500. Healthcare professionals, consumers, and manufacturers can all submit reports. Reporting helps the FDA monitor drug safety after approval.

What is Oxybutynin Chloride's safety score and what does it mean?

Oxybutynin Chloride has a safety concern score of 65 out of 100 (elevated concern). This score is calculated from the ratio of serious to non-serious adverse events, the diversity of reported reactions, and the overall volume of reports relative to usage. Fatigue and dizziness are common, indicating potential cognitive and physical impacts.

What are the key safety signals for Oxybutynin Chloride?

Key safety signals identified in Oxybutynin Chloride's adverse event data include: Frequent reports of falls and dizziness suggest a risk of falls and accidents.. Gastrointestinal issues are common, which could impact quality of life.. Serious adverse events like pneumonia and death are reported but less frequent.. Drug interactions and dose omissions are noted, indicating potential misuse or interaction risks.. These signals are derived from patterns in FDA reports and should be discussed with a healthcare provider for personalized assessment.

Does Oxybutynin Chloride interact with other drugs?

Oxybutynin Chloride can cause dizziness and fatigue, which may increase the risk of falls and accidents. Patients should avoid driving or operating heavy machinery until they know how the drug affects them. Always inform your healthcare provider about all medications, supplements, and over-the-counter drugs you are taking before starting Oxybutynin Chloride.

What should patients know before taking Oxybutynin Chloride?

Patients should report any unusual symptoms to their healthcare provider immediately. Avoid driving or operating heavy machinery if you experience dizziness or fatigue.

Are Oxybutynin Chloride side effects well-documented?

Oxybutynin Chloride has 19,830 adverse event reports on file with the FDA. Gastrointestinal issues like nausea, diarrhea, and constipation are frequent. The volume of reports for Oxybutynin Chloride reflects both the drug's usage level and the vigilance of the reporting community.

What is the FDA's position on Oxybutynin Chloride?

The FDA continues to monitor Oxybutynin Chloride for safety. Healthcare providers should be aware of the potential for serious adverse events and monitor patients closely. For the most current regulatory information, check the FDA's drug labeling database or consult your pharmacist.

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Important Disclaimer: This content is generated by AI analysis of FDA adverse event reports and is provided for informational purposes only. It is not medical advice. Adverse event reports submitted to the FDA do not prove that a medication caused the reported side effect. Always consult your healthcare provider before starting, stopping, or changing any medication. If you experience a serious side effect, contact your doctor or call 911 immediately.