SODIUM CHLORIDE TABLETS

85/100 · Critical

Manufactured by Kesin Pharma Corporation

High Safety Concerns with Sodium Chloride Tablets

143,106 FDA adverse event reports analyzed

Last updated: 2026-05-12

About SODIUM CHLORIDE TABLETS

SODIUM CHLORIDE TABLETS is a medication tracked in the FDA Adverse Event Reporting System (FAERS), manufactured by Kesin Pharma Corporation. Based on analysis of 143,106 FDA adverse event reports, SODIUM CHLORIDE TABLETS has a safety score of 85 out of 100. This score indicates a relatively favorable safety profile, with fewer or less severe adverse events compared to many other tracked medications. The most commonly reported adverse reactions for SODIUM CHLORIDE TABLETS include NAUSEA, MYELOSUPPRESSION, DYSPNOEA, OFF LABEL USE, HEADACHE. This page provides a comprehensive breakdown of reported side effects, safety signals, patient demographics, and AI-powered safety analysis for SODIUM CHLORIDE TABLETS.

AI Safety Analysis

Sodium Chloride Tablets has a safety concern score of 85 out of 100, placing it in the high concern category based on analysis of FDA adverse event data. The FDA has received approximately 143,106 adverse event reports for this medication, which is primarily manufactured by Kesin Pharma Corporation.

The most commonly reported adverse events include Nausea, Myelosuppression, Dyspnoea. Of classified reports, 80.9% were designated as serious by the FDA, meaning they involved hospitalization, disability, or other significant medical outcomes. Severe reactions such as pneumonia, sepsis, and respiratory failure are common.

Significant drops in white blood cell count and platelet count are frequent. A high number of serious adverse events (80.9%) indicate potential risks. Multiple drug interactions and warnings are present, especially for elderly patients. Regulatory oversight is necessary given the high volume of adverse reports.

Patients taking Sodium Chloride Tablets should monitor for the commonly reported side effects and contact their healthcare provider if they experience any unusual symptoms. Sodium Chloride Tablets can cause severe reactions such as pneumonia, sepsis, and respiratory failure. Warnings are particularly important for elderly patients and those with pre-existing conditions. This analysis is based on voluntary FDA adverse event reports and should not replace professional medical advice.

Safety Score: 85/100

Sodium Chloride Tablets received a safety concern score of 85/100 (high concern). This is based on a 80.9% serious event ratio across 67,832 classified reports. The score accounts for 143,106 total adverse event reports and 100 distinct reaction types. This high score reflects a significant proportion of serious adverse events in the reporting data.

Top Adverse Reactions

NAUSEA4,885 reports
MYELOSUPPRESSION4,444 reports
DYSPNOEA4,211 reports
OFF LABEL USE4,202 reports
HEADACHE3,964 reports
PYREXIA3,912 reports
FATIGUE3,744 reports
VOMITING3,495 reports
DIARRHOEA3,359 reports
PNEUMONIA3,146 reports
PAIN2,709 reports
WHITE BLOOD CELL COUNT DECREASED2,626 reports
COUGH2,305 reports
DRUG INEFFECTIVE2,288 reports
DIZZINESS2,174 reports
ASTHENIA2,083 reports
MALAISE1,973 reports
COVID 191,883 reports
RASH1,883 reports
PRURITUS1,873 reports
PRODUCT DOSE OMISSION ISSUE1,857 reports
DEATH1,812 reports
SINUSITIS1,806 reports
WEIGHT DECREASED1,772 reports
FALL1,760 reports
URINARY TRACT INFECTION1,645 reports
HYPOTENSION1,627 reports
INFUSION RELATED REACTION1,599 reports
ABDOMINAL PAIN1,562 reports
CHILLS1,556 reports
DECREASED APPETITE1,553 reports
CHEST DISCOMFORT1,492 reports
NEUTROPHIL COUNT DECREASED1,452 reports
ANAEMIA1,436 reports
ACUTE KIDNEY INJURY1,429 reports
NASOPHARYNGITIS1,416 reports
BACK PAIN1,411 reports
INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION1,330 reports
ARTHRALGIA1,311 reports
PLATELET COUNT DECREASED1,288 reports
HYPERTENSION1,257 reports
INFECTION1,254 reports
PAIN IN EXTREMITY1,241 reports
PRODUCT USE IN UNAPPROVED INDICATION1,232 reports
SEPSIS1,215 reports
CONDITION AGGRAVATED1,203 reports
ANXIETY1,159 reports
CONSTIPATION1,146 reports
ERYTHEMA1,117 reports
CHEST PAIN1,098 reports
INFUSION SITE PAIN1,050 reports
HYPONATRAEMIA1,005 reports
BLOOD PRESSURE INCREASED1,000 reports
WEIGHT INCREASED996 reports
PRODUCT USE ISSUE984 reports
DEHYDRATION981 reports
ILLNESS978 reports
INFLUENZA954 reports
HEPATIC FUNCTION ABNORMAL940 reports
HOSPITALISATION903 reports
OEDEMA PERIPHERAL882 reports
UPPER RESPIRATORY TRACT INFECTION872 reports
OXYGEN SATURATION DECREASED860 reports
FEBRILE NEUTROPENIA846 reports
BRONCHITIS820 reports
ABDOMINAL DISTENSION818 reports
HYPERSENSITIVITY818 reports
FLUSHING813 reports
DRUG HYPERSENSITIVITY775 reports
HAEMOGLOBIN DECREASED774 reports
PRODUCTIVE COUGH770 reports
PERIPHERAL SWELLING767 reports
INFECTIVE PULMONARY EXACERBATION OF CYSTIC FIBROSIS765 reports
THROMBOCYTOPENIA760 reports
URTICARIA756 reports
HEREDITARY ANGIOEDEMA755 reports
TREMOR748 reports
RESPIRATORY FAILURE744 reports
SOMNOLENCE743 reports
RENAL FAILURE738 reports
FEELING ABNORMAL734 reports
HEART RATE INCREASED734 reports
TACHYCARDIA727 reports
SEIZURE726 reports
ABDOMINAL PAIN UPPER722 reports
NEUTROPENIA722 reports
HYPOKALAEMIA706 reports
CONFUSIONAL STATE685 reports
INSOMNIA664 reports
ASTHMA659 reports
ABDOMINAL DISCOMFORT653 reports
INFUSION SITE ERYTHEMA636 reports
MUSCLE SPASMS632 reports
OROPHARYNGEAL PAIN630 reports
HYPOAESTHESIA624 reports
DYSPEPSIA622 reports
MIGRAINE616 reports
PALPITATIONS607 reports
INSURANCE ISSUE599 reports
RESPIRATORY TRACT INFECTION598 reports

Key Safety Signals

  • High frequency of serious reactions (54,845 out of 67,832, 80.9%)
  • Multiple blood count abnormalities (white blood cell, platelet, and neutrophil decreases)
  • Common reactions include pneumonia, sepsis, and respiratory failure
  • Significant number of reports involving drug ineffectiveness and inappropriate use
  • Elderly patients (ages 65-73) are disproportionately affected

Patient Demographics

Adverse event reports by sex: Female: 36,061, Male: 25,650, Unknown: 69. The most frequently reported age groups are age 54 (1,010 reports), age 65 (1,000 reports), age 67 (995 reports). These demographics reflect reporting patterns and may not represent the full patient population.

Report Outcomes

Out of 67,832 classified reports for SODIUM CHLORIDE TABLETS:

  • Serious: 54,845 reports (80.9%) — includes hospitalization, disability, life-threatening events, or death
  • Non-Serious: 12,987 reports (19.1%)
Serious 80.9%Non-Serious 19.1%

The FDA classifies an adverse event as “serious” if it results in death, hospitalization, disability, congenital anomaly, or requires intervention to prevent permanent damage.

Demographics Breakdown

Reports by Sex

Female36,061 (58.4%)
Male25,650 (41.5%)
Unknown69 (0.1%)

Reports by Age

Age 541,010 reports
Age 651,000 reports
Age 67995 reports
Age 68987 reports
Age 71985 reports
Age 62980 reports
Age 70974 reports
Age 66962 reports
Age 72946 reports
Age 64945 reports
Age 69935 reports
Age 73934 reports
Age 57929 reports
Age 60928 reports
Age 58923 reports
Age 59908 reports
Age 61904 reports
Age 63899 reports
Age 56854 reports
Age 55828 reports

Demographics reflect voluntary FDA adverse event reporting patterns and may not represent the full patient population.

Drug Interactions & Warnings

Sodium Chloride Tablets can cause severe reactions such as pneumonia, sepsis, and respiratory failure. Warnings are particularly important for elderly patients and those with pre-existing conditions.

What You Should Know

If you are taking Sodium Chloride Tablets, here are important things to know. The most commonly reported side effects include nausea, myelosuppression, dyspnoea, off label use, headache. While many of these may be mild and temporary, you should contact your healthcare provider if any symptoms are severe or persistent. Patients should report any severe symptoms to their healthcare provider immediately. Follow prescribed dosing instructions and do not use the product for unapproved indications. If you experience a serious adverse reaction, seek emergency medical attention immediately or call 911. You can report side effects to the FDA's MedWatch program at 1-800-FDA-1088.

Regulatory Context

The FDA should closely monitor the safety of Sodium Chloride Tablets, especially in elderly and immunocompromised patients. Healthcare providers should be vigilant about potential serious adverse events and ensure proper use.

Frequently Asked Questions

How many adverse event reports has the FDA received for Sodium Chloride Tablets?

The FDA has received approximately 143,106 adverse event reports associated with Sodium Chloride Tablets. These reports come from healthcare professionals, consumers, and manufacturers through the FDA Adverse Event Reporting System (FAERS). Note that the number of reports does not directly indicate the frequency of side effects, as adverse events are voluntarily reported and may be underrepresented.

What are the most commonly reported side effects of Sodium Chloride Tablets?

The most frequently reported adverse events for Sodium Chloride Tablets include Nausea, Myelosuppression, Dyspnoea, Off Label Use, Headache. By volume, the top reported reactions are: Nausea (4,885 reports), Myelosuppression (4,444 reports), Dyspnoea (4,211 reports). These figures reflect FDA adverse event reports and may not represent the true incidence rate of these side effects in all patients taking Sodium Chloride Tablets.

What percentage of Sodium Chloride Tablets adverse event reports are serious?

Out of 67,832 classified reports, 54,845 (80.9%) were classified as serious and 12,987 as non-serious. The FDA classifies an event as "serious" if it results in death, hospitalization, disability, or other medically significant outcomes. A higher serious-event ratio warrants closer attention but does not necessarily mean the drug is unsafe.

Who reports adverse events for Sodium Chloride Tablets (by sex)?

Adverse event reports for Sodium Chloride Tablets break down by patient sex as follows: Female: 36,061, Male: 25,650, Unknown: 69. This distribution reflects reporting patterns rather than actual risk differences between groups. Reporting rates can be influenced by prescribing patterns, disease demographics, and reporting behavior.

What age groups report the most side effects for Sodium Chloride Tablets?

The most frequently reported age groups for Sodium Chloride Tablets adverse events are: age 54: 1,010 reports, age 65: 1,000 reports, age 67: 995 reports, age 68: 987 reports, age 71: 985 reports. Age-related reporting patterns can reflect both the demographics of the patient population and potential age-related susceptibility to certain side effects.

Who manufactures Sodium Chloride Tablets?

The primary manufacturer associated with Sodium Chloride Tablets adverse event reports is Kesin Pharma Corporation. Multiple manufacturers may produce generic versions of this drug. The manufacturer listed reflects the most frequently reported brand in FDA adverse event data.

What other side effects have been reported for Sodium Chloride Tablets?

Beyond the most common reactions, other reported adverse events for Sodium Chloride Tablets include: Pyrexia, Fatigue, Vomiting, Diarrhoea, Pneumonia. Less common side effects can still be clinically significant. Patients should report any unusual symptoms to their healthcare provider.

How do I report a side effect from Sodium Chloride Tablets?

You can report adverse events from Sodium Chloride Tablets to the FDA through their MedWatch program at www.fda.gov/medwatch, by calling 1-800-FDA-1088, or by completing Form FDA 3500. Healthcare professionals, consumers, and manufacturers can all submit reports. Reporting helps the FDA monitor drug safety after approval.

What is Sodium Chloride Tablets's safety score and what does it mean?

Sodium Chloride Tablets has a safety concern score of 85 out of 100 (high concern). This score is calculated from the ratio of serious to non-serious adverse events, the diversity of reported reactions, and the overall volume of reports relative to usage. Severe reactions such as pneumonia, sepsis, and respiratory failure are common.

What are the key safety signals for Sodium Chloride Tablets?

Key safety signals identified in Sodium Chloride Tablets's adverse event data include: High frequency of serious reactions (54,845 out of 67,832, 80.9%). Multiple blood count abnormalities (white blood cell, platelet, and neutrophil decreases). Common reactions include pneumonia, sepsis, and respiratory failure. Significant number of reports involving drug ineffectiveness and inappropriate use. Elderly patients (ages 65-73) are disproportionately affected. These signals are derived from patterns in FDA reports and should be discussed with a healthcare provider for personalized assessment.

Does Sodium Chloride Tablets interact with other drugs?

Sodium Chloride Tablets can cause severe reactions such as pneumonia, sepsis, and respiratory failure. Warnings are particularly important for elderly patients and those with pre-existing conditions. Always inform your healthcare provider about all medications, supplements, and over-the-counter drugs you are taking before starting Sodium Chloride Tablets.

What should patients know before taking Sodium Chloride Tablets?

Patients should report any severe symptoms to their healthcare provider immediately. Follow prescribed dosing instructions and do not use the product for unapproved indications.

Are Sodium Chloride Tablets side effects well-documented?

Sodium Chloride Tablets has 143,106 adverse event reports on file with the FDA. Significant drops in white blood cell count and platelet count are frequent. The volume of reports for Sodium Chloride Tablets reflects both the drug's usage level and the vigilance of the reporting community.

What is the FDA's position on Sodium Chloride Tablets?

The FDA should closely monitor the safety of Sodium Chloride Tablets, especially in elderly and immunocompromised patients. Healthcare providers should be vigilant about potential serious adverse events and ensure proper use. For the most current regulatory information, check the FDA's drug labeling database or consult your pharmacist.

Related Drugs

Drugs related to SODIUM CHLORIDE TABLETS based on therapeutic use, drug class, or shared indications:

Kesin Pharma CorporationFDAHealthcare Providers
Important Disclaimer: This content is generated by AI analysis of FDA adverse event reports and is provided for informational purposes only. It is not medical advice. Adverse event reports submitted to the FDA do not prove that a medication caused the reported side effect. Always consult your healthcare provider before starting, stopping, or changing any medication. If you experience a serious side effect, contact your doctor or call 911 immediately.