SODIUM SULFATE

25/100 · Low Risk

Sodium Sulfate Adverse Events: Common Mild Reactions

1,477 FDA adverse event reports analyzed

Last updated: 2026-05-12

About SODIUM SULFATE

SODIUM SULFATE is a medication tracked in the FDA Adverse Event Reporting System (FAERS). Based on analysis of 1,477 FDA adverse event reports, SODIUM SULFATE has a safety score of 25 out of 100. This lower score reflects a significant number of adverse event reports, suggesting that patients should discuss potential risks carefully with their healthcare provider. The most commonly reported adverse reactions for SODIUM SULFATE include PAIN, NAUSEA, HEADACHE, DRUG INEFFECTIVE, DIARRHOEA. This page provides a comprehensive breakdown of reported side effects, safety signals, patient demographics, and AI-powered safety analysis for SODIUM SULFATE.

AI Safety Analysis

Sodium Sulfate has a safety concern score of 25 out of 100, placing it in the low concern category based on analysis of FDA adverse event data. The FDA has received approximately 1,477 adverse event reports for this medication.

The most commonly reported adverse events include Pain, Nausea, Headache. The most common reactions are pain, nausea, and headache, indicating mild to moderate side effects.

The majority of reactions are non-serious, with the majority of reports involving pain and gastrointestinal issues. There is a notable diversity in reactions, suggesting a wide range of potential side effects. The majority of reports are from adults, with the highest number of reports coming from individuals in their 60s and 70s.

Patients taking Sodium Sulfate should monitor for the commonly reported side effects and contact their healthcare provider if they experience any unusual symptoms. Sodium sulfate is generally well-tolerated, but it may interact with other drugs, particularly those affecting electrolyte balance. Warnings should be followed to avoid adverse interactions. This analysis is based on voluntary FDA adverse event reports and should not replace professional medical advice.

Safety Score: 25/100

Sodium Sulfate received a safety concern score of 25/100 (low concern). The score accounts for 1,477 total adverse event reports and 100 distinct reaction types. This relatively low score suggests a favorable safety profile in reported data.

Top Adverse Reactions

PAIN47 reports
NAUSEA46 reports
HEADACHE44 reports
DRUG INEFFECTIVE43 reports
DIARRHOEA42 reports
FATIGUE38 reports
OFF LABEL USE35 reports
CONSTIPATION31 reports
MALAISE28 reports
ARTHRALGIA27 reports
DIZZINESS27 reports
DYSPNOEA25 reports
WEIGHT DECREASED23 reports
PAIN IN EXTREMITY22 reports
ABDOMINAL PAIN UPPER21 reports
VOMITING21 reports
ASTHENIA20 reports
MUSCLE SPASMS20 reports
PNEUMONIA20 reports
ABDOMINAL PAIN19 reports
FALL19 reports
INSOMNIA19 reports
PRODUCT DOSE OMISSION ISSUE19 reports
DEPRESSION18 reports
DYSPEPSIA18 reports
FEELING ABNORMAL18 reports
PRURITUS18 reports
PYREXIA18 reports
ANAEMIA17 reports
DEATH17 reports
EYE PAIN17 reports
GAIT DISTURBANCE17 reports
MACULAR DEGENERATION17 reports
RASH17 reports
ALOPECIA15 reports
CONDITION AGGRAVATED14 reports
HYPOAESTHESIA14 reports
INTENTIONAL PRODUCT MISUSE14 reports
PARAESTHESIA14 reports
WEIGHT INCREASED14 reports
BACK PAIN13 reports
BLOOD PRESSURE INCREASED13 reports
DECREASED APPETITE13 reports
SOMNOLENCE13 reports
TREMOR13 reports
VISION BLURRED13 reports
ANXIETY11 reports
CONFUSIONAL STATE11 reports
DRUG HYPERSENSITIVITY11 reports
ERYTHEMA11 reports
FLUSHING11 reports
PRODUCT SUBSTITUTION ISSUE11 reports
BALANCE DISORDER10 reports
DRUG INTOLERANCE10 reports
INFUSION RELATED REACTION10 reports
MIGRAINE10 reports
MULTIPLE SCLEROSIS RELAPSE10 reports
PERIPHERAL SWELLING10 reports
PROCEDURAL PAIN10 reports
THERAPEUTIC PRODUCT EFFECT INCOMPLETE10 reports
ABDOMINAL DISCOMFORT9 reports
CHRONIC SINUSITIS9 reports
CONTUSION9 reports
FREQUENT BOWEL MOVEMENTS9 reports
PALPITATIONS9 reports
PARAESTHESIA ORAL9 reports
PRODUCT DOSE OMISSION9 reports
RECTAL HAEMORRHAGE9 reports
SEPSIS9 reports
SKIN EXFOLIATION9 reports
THROMBOSIS9 reports
ACUTE KIDNEY INJURY8 reports
CHRONIC OBSTRUCTIVE PULMONARY DISEASE8 reports
COLITIS8 reports
COUGH8 reports
COVID 198 reports
DRY MOUTH8 reports
HAEMATOCHEZIA8 reports
HOT FLUSH8 reports
HYPERTENSION8 reports
MULTIPLE ORGAN DYSFUNCTION SYNDROME8 reports
MUSCULOSKELETAL STIFFNESS8 reports
NEUROPATHY PERIPHERAL8 reports
PULMONARY EMBOLISM8 reports
SEIZURE8 reports
SLEEP DISORDER8 reports
STRESS8 reports
SWELLING8 reports
URTICARIA8 reports
BLOOD GLUCOSE INCREASED7 reports
CHEST PAIN7 reports
CHILLS7 reports
CHRONIC KIDNEY DISEASE7 reports
COLITIS ULCERATIVE7 reports
DEHYDRATION7 reports
DRUG DOSE OMISSION7 reports
EPIGASTRIC DISCOMFORT7 reports
FEMALE GENITAL TRACT FISTULA7 reports
GASTROINTESTINAL DISORDER7 reports
GASTROOESOPHAGEAL REFLUX DISEASE7 reports

Key Safety Signals

  • Pain is the most frequently reported reaction, occurring in 3.2% of reports.
  • Gastrointestinal issues such as nausea, diarrhea, and abdominal pain are also common, appearing in 3.1% of reports each.
  • There is a significant number of reports related to drug ineffectiveness, indicating potential issues with the product's efficacy.

Patient Demographics

Adverse event reports by sex: Female: 396, Male: 167. The most frequently reported age groups are age 70 (22 reports), age 65 (17 reports), age 66 (16 reports). These demographics reflect reporting patterns and may not represent the full patient population.

Demographics Breakdown

Reports by Sex

Female396 (70.3%)
Male167 (29.7%)

Reports by Age

Age 7022 reports
Age 6517 reports
Age 6616 reports
Age 6816 reports
Age 6415 reports
Age 7115 reports
Age 7215 reports
Age 7514 reports
Age 5813 reports
Age 6112 reports
Age 6912 reports
Age 7412 reports
Age 7612 reports
Age 7311 reports
Age 5910 reports
Age 8110 reports
Age 8210 reports
Age 529 reports
Age 548 reports
Age 608 reports

Demographics reflect voluntary FDA adverse event reporting patterns and may not represent the full patient population.

Drug Interactions & Warnings

Sodium sulfate is generally well-tolerated, but it may interact with other drugs, particularly those affecting electrolyte balance. Warnings should be followed to avoid adverse interactions.

What You Should Know

If you are taking Sodium Sulfate, here are important things to know. The most commonly reported side effects include pain, nausea, headache, drug ineffective, diarrhoea. While many of these may be mild and temporary, you should contact your healthcare provider if any symptoms are severe or persistent. Monitor for signs of gastrointestinal distress and pain, and report any severe or persistent symptoms to a healthcare provider. Follow the prescribed dosage and instructions to avoid drug ineffectiveness and other potential side effects. If you experience a serious adverse reaction, seek emergency medical attention immediately or call 911. You can report side effects to the FDA's MedWatch program at 1-800-FDA-1088.

Regulatory Context

The FDA continues to monitor sodium sulfate for safety, and updates will be provided as necessary. Patients should report any adverse reactions to their healthcare provider.

Frequently Asked Questions

How many adverse event reports has the FDA received for Sodium Sulfate?

The FDA has received approximately 1,477 adverse event reports associated with Sodium Sulfate. These reports come from healthcare professionals, consumers, and manufacturers through the FDA Adverse Event Reporting System (FAERS). Note that the number of reports does not directly indicate the frequency of side effects, as adverse events are voluntarily reported and may be underrepresented.

What are the most commonly reported side effects of Sodium Sulfate?

The most frequently reported adverse events for Sodium Sulfate include Pain, Nausea, Headache, Drug Ineffective, Diarrhoea. By volume, the top reported reactions are: Pain (47 reports), Nausea (46 reports), Headache (44 reports). These figures reflect FDA adverse event reports and may not represent the true incidence rate of these side effects in all patients taking Sodium Sulfate.

Who reports adverse events for Sodium Sulfate (by sex)?

Adverse event reports for Sodium Sulfate break down by patient sex as follows: Female: 396, Male: 167. This distribution reflects reporting patterns rather than actual risk differences between groups. Reporting rates can be influenced by prescribing patterns, disease demographics, and reporting behavior.

What age groups report the most side effects for Sodium Sulfate?

The most frequently reported age groups for Sodium Sulfate adverse events are: age 70: 22 reports, age 65: 17 reports, age 66: 16 reports, age 68: 16 reports, age 64: 15 reports. Age-related reporting patterns can reflect both the demographics of the patient population and potential age-related susceptibility to certain side effects.

What other side effects have been reported for Sodium Sulfate?

Beyond the most common reactions, other reported adverse events for Sodium Sulfate include: Fatigue, Off Label Use, Constipation, Malaise, Arthralgia. Less common side effects can still be clinically significant. Patients should report any unusual symptoms to their healthcare provider.

How do I report a side effect from Sodium Sulfate?

You can report adverse events from Sodium Sulfate to the FDA through their MedWatch program at www.fda.gov/medwatch, by calling 1-800-FDA-1088, or by completing Form FDA 3500. Healthcare professionals, consumers, and manufacturers can all submit reports. Reporting helps the FDA monitor drug safety after approval.

What is Sodium Sulfate's safety score and what does it mean?

Sodium Sulfate has a safety concern score of 25 out of 100 (low concern). This score is calculated from the ratio of serious to non-serious adverse events, the diversity of reported reactions, and the overall volume of reports relative to usage. The most common reactions are pain, nausea, and headache, indicating mild to moderate side effects.

What are the key safety signals for Sodium Sulfate?

Key safety signals identified in Sodium Sulfate's adverse event data include: Pain is the most frequently reported reaction, occurring in 3.2% of reports.. Gastrointestinal issues such as nausea, diarrhea, and abdominal pain are also common, appearing in 3.1% of reports each.. There is a significant number of reports related to drug ineffectiveness, indicating potential issues with the product's efficacy.. These signals are derived from patterns in FDA reports and should be discussed with a healthcare provider for personalized assessment.

Does Sodium Sulfate interact with other drugs?

Sodium sulfate is generally well-tolerated, but it may interact with other drugs, particularly those affecting electrolyte balance. Warnings should be followed to avoid adverse interactions. Always inform your healthcare provider about all medications, supplements, and over-the-counter drugs you are taking before starting Sodium Sulfate.

What should patients know before taking Sodium Sulfate?

Monitor for signs of gastrointestinal distress and pain, and report any severe or persistent symptoms to a healthcare provider. Follow the prescribed dosage and instructions to avoid drug ineffectiveness and other potential side effects.

Are Sodium Sulfate side effects well-documented?

Sodium Sulfate has 1,477 adverse event reports on file with the FDA. The majority of reactions are non-serious, with the majority of reports involving pain and gastrointestinal issues. The volume of reports for Sodium Sulfate reflects both the drug's usage level and the vigilance of the reporting community.

What is the FDA's position on Sodium Sulfate?

The FDA continues to monitor sodium sulfate for safety, and updates will be provided as necessary. Patients should report any adverse reactions to their healthcare provider. For the most current regulatory information, check the FDA's drug labeling database or consult your pharmacist.

Related Drugs

Drugs related to SODIUM SULFATE based on therapeutic use, drug class, or shared indications:

AcetaminophenIbuprofenLoperamide
Important Disclaimer: This content is generated by AI analysis of FDA adverse event reports and is provided for informational purposes only. It is not medical advice. Adverse event reports submitted to the FDA do not prove that a medication caused the reported side effect. Always consult your healthcare provider before starting, stopping, or changing any medication. If you experience a serious side effect, contact your doctor or call 911 immediately.