SUCRALFATE ORAL SUSPENSION

65/100 · Elevated

Manufactured by Glenmark Pharmaceuticals Inc., USA

Moderate Safety Concerns with SUCRALFATE ORAL SUSPENSION

33,485 FDA adverse event reports analyzed

Last updated: 2026-05-12

About SUCRALFATE ORAL SUSPENSION

SUCRALFATE ORAL SUSPENSION is a medication tracked in the FDA Adverse Event Reporting System (FAERS), manufactured by Glenmark Pharmaceuticals Inc., USA. Based on analysis of 33,485 FDA adverse event reports, SUCRALFATE ORAL SUSPENSION has a safety score of 65 out of 100. This moderate score indicates a notable volume of adverse event reports that patients and providers should be aware of. The most commonly reported adverse reactions for SUCRALFATE ORAL SUSPENSION include NAUSEA, DIARRHOEA, FATIGUE, PAIN, HEADACHE. This page provides a comprehensive breakdown of reported side effects, safety signals, patient demographics, and AI-powered safety analysis for SUCRALFATE ORAL SUSPENSION.

AI Safety Analysis

Sucralfate Oral Suspension has a safety concern score of 65 out of 100, placing it in the elevated concern category based on analysis of FDA adverse event data. The FDA has received approximately 33,485 adverse event reports for this medication, which is primarily manufactured by Glenmark Pharmaceuticals Inc., Usa.

The most commonly reported adverse events include Nausea, Diarrhoea, Fatigue. Of classified reports, 71.5% were designated as serious by the FDA, meaning they involved hospitalization, disability, or other significant medical outcomes. The most common reactions include nausea, diarrhea, and fatigue, indicating gastrointestinal side effects are prevalent.

Serious reactions such as chronic kidney disease, renal failure, and death are reported, though less frequently. Drug ineffectiveness and off-label use are also significant concerns, suggesting potential misuse or inefficacy issues. A wide range of reactions, including respiratory and neurological issues, indicates a diverse safety profile. Weight changes, both increase and decrease, are reported, suggesting potential impact on body weight.

Patients taking Sucralfate Oral Suspension should monitor for the commonly reported side effects and contact their healthcare provider if they experience any unusual symptoms. Warnings include potential drug interactions and the need for appropriate use to avoid off-label use and drug ineffectiveness. This analysis is based on voluntary FDA adverse event reports and should not replace professional medical advice.

Safety Score: 65/100

Sucralfate Oral Suspension received a safety concern score of 65/100 (elevated concern). This is based on a 71.5% serious event ratio across 13,538 classified reports. The score accounts for 33,485 total adverse event reports and 100 distinct reaction types. This elevated score indicates a notable proportion of serious adverse events and warrants careful monitoring.

Top Adverse Reactions

NAUSEA1,370 reports
DIARRHOEA987 reports
FATIGUE985 reports
PAIN899 reports
HEADACHE875 reports
OFF LABEL USE807 reports
DRUG INEFFECTIVE785 reports
VOMITING775 reports
DYSPNOEA757 reports
CHRONIC KIDNEY DISEASE666 reports
WEIGHT DECREASED621 reports
DIZZINESS605 reports
ABDOMINAL PAIN597 reports
MALAISE591 reports
CONSTIPATION565 reports
PNEUMONIA562 reports
ASTHENIA553 reports
RENAL FAILURE526 reports
PYREXIA524 reports
DEATH507 reports
ACUTE KIDNEY INJURY495 reports
ANAEMIA487 reports
FALL481 reports
ARTHRALGIA455 reports
ABDOMINAL PAIN UPPER432 reports
COUGH416 reports
GASTROOESOPHAGEAL REFLUX DISEASE408 reports
DECREASED APPETITE389 reports
ANXIETY382 reports
BACK PAIN372 reports
RASH367 reports
URINARY TRACT INFECTION342 reports
CONDITION AGGRAVATED331 reports
PAIN IN EXTREMITY329 reports
DYSPEPSIA328 reports
CHEST PAIN324 reports
ERYTHEMA307 reports
DEPRESSION304 reports
DEHYDRATION298 reports
PRURITUS285 reports
ABDOMINAL DISCOMFORT278 reports
PRODUCT DOSE OMISSION ISSUE278 reports
HYPOTENSION273 reports
INSOMNIA262 reports
HYPERTENSION261 reports
GASTROINTESTINAL HAEMORRHAGE253 reports
HAEMATOCHEZIA250 reports
MUSCLE SPASMS239 reports
WEIGHT INCREASED239 reports
RECTAL HAEMORRHAGE237 reports
FEELING ABNORMAL225 reports
PERIPHERAL SWELLING218 reports
NASOPHARYNGITIS215 reports
COLITIS213 reports
HAEMOGLOBIN DECREASED212 reports
BLOOD PRESSURE INCREASED210 reports
DYSPHAGIA210 reports
GAIT DISTURBANCE206 reports
SINUSITIS201 reports
ABDOMINAL DISTENSION196 reports
FREQUENT BOWEL MOVEMENTS196 reports
INFECTION196 reports
COVID 19191 reports
SEPSIS189 reports
ORAL CANDIDIASIS188 reports
INFUSION RELATED REACTION187 reports
COLITIS ULCERATIVE183 reports
PRODUCT USE IN UNAPPROVED INDICATION183 reports
TREMOR183 reports
HYPOAESTHESIA182 reports
DRUG INTERACTION179 reports
CONFUSIONAL STATE178 reports
SOMNOLENCE178 reports
OROPHARYNGEAL PAIN177 reports
INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION176 reports
BRONCHITIS175 reports
MEMORY IMPAIRMENT175 reports
OEDEMA PERIPHERAL175 reports
MYALGIA172 reports
END STAGE RENAL DISEASE171 reports
GASTRITIS170 reports
VAGINAL DISCHARGE165 reports
RADICULOPATHY164 reports
FEMALE GENITAL TRACT FISTULA162 reports
PROCTITIS161 reports
FEBRILE NEUTROPENIA158 reports
PLATELET COUNT DECREASED158 reports
VAGINAL FLATULENCE157 reports
THERAPEUTIC PRODUCT EFFECT INCOMPLETE154 reports
DRUG HYPERSENSITIVITY153 reports
GASTROINTESTINAL DISORDER152 reports
ATRIAL FIBRILLATION151 reports
RENAL INJURY151 reports
LOSS OF CONSCIOUSNESS150 reports
ALOPECIA149 reports
HOSPITALISATION148 reports
DISEASE PROGRESSION147 reports
CHRONIC SINUSITIS146 reports
DRY MOUTH145 reports
ILLNESS145 reports

Key Safety Signals

  • Chronic kidney disease and renal failure are reported as serious adverse events.
  • Death and severe infections like sepsis are noted, indicating potential life-threatening risks.
  • Drug ineffectiveness and off-label use suggest misuse or inefficacy issues.
  • A variety of neurological and respiratory symptoms are reported, indicating a broad range of potential side effects.
  • Weight changes, both increase and decrease, are reported, suggesting potential impact on body weight.

Patient Demographics

Adverse event reports by sex: Female: 8,236, Male: 4,438, Unknown: 19. The most frequently reported age groups are age 65 (308 reports), age 64 (281 reports), age 71 (271 reports). These demographics reflect reporting patterns and may not represent the full patient population.

Report Outcomes

Out of 13,538 classified reports for SUCRALFATE ORAL SUSPENSION:

  • Serious: 9,673 reports (71.5%) — includes hospitalization, disability, life-threatening events, or death
  • Non-Serious: 3,865 reports (28.5%)
Serious 71.5%Non-Serious 28.5%

The FDA classifies an adverse event as “serious” if it results in death, hospitalization, disability, congenital anomaly, or requires intervention to prevent permanent damage.

Demographics Breakdown

Reports by Sex

Female8,236 (64.9%)
Male4,438 (35.0%)
Unknown19 (0.1%)

Reports by Age

Age 65308 reports
Age 64281 reports
Age 71271 reports
Age 63253 reports
Age 66251 reports
Age 62244 reports
Age 69240 reports
Age 67229 reports
Age 70222 reports
Age 72221 reports
Age 60214 reports
Age 61208 reports
Age 68205 reports
Age 73203 reports
Age 58199 reports
Age 59198 reports
Age 57193 reports
Age 74192 reports
Age 75182 reports
Age 76180 reports

Demographics reflect voluntary FDA adverse event reporting patterns and may not represent the full patient population.

Drug Interactions & Warnings

Warnings include potential drug interactions and the need for appropriate use to avoid off-label use and drug ineffectiveness.

What You Should Know

If you are taking Sucralfate Oral Suspension, here are important things to know. The most commonly reported side effects include nausea, diarrhoea, fatigue, pain, headache. While many of these may be mild and temporary, you should contact your healthcare provider if any symptoms are severe or persistent. Patients should report any severe or unusual symptoms to their healthcare provider immediately. Follow prescribed dosing instructions and do not use the product for unapproved indications. If you experience a serious adverse reaction, seek emergency medical attention immediately or call 911. You can report side effects to the FDA's MedWatch program at 1-800-FDA-1088.

Regulatory Context

The FDA continues to monitor the safety of SUCRALFATE ORAL SUSPENSION, and healthcare providers should be vigilant about patient safety and proper use.

Frequently Asked Questions

How many adverse event reports has the FDA received for Sucralfate Oral Suspension?

The FDA has received approximately 33,485 adverse event reports associated with Sucralfate Oral Suspension. These reports come from healthcare professionals, consumers, and manufacturers through the FDA Adverse Event Reporting System (FAERS). Note that the number of reports does not directly indicate the frequency of side effects, as adverse events are voluntarily reported and may be underrepresented.

What are the most commonly reported side effects of Sucralfate Oral Suspension?

The most frequently reported adverse events for Sucralfate Oral Suspension include Nausea, Diarrhoea, Fatigue, Pain, Headache. By volume, the top reported reactions are: Nausea (1,370 reports), Diarrhoea (987 reports), Fatigue (985 reports). These figures reflect FDA adverse event reports and may not represent the true incidence rate of these side effects in all patients taking Sucralfate Oral Suspension.

What percentage of Sucralfate Oral Suspension adverse event reports are serious?

Out of 13,538 classified reports, 9,673 (71.5%) were classified as serious and 3,865 as non-serious. The FDA classifies an event as "serious" if it results in death, hospitalization, disability, or other medically significant outcomes. A higher serious-event ratio warrants closer attention but does not necessarily mean the drug is unsafe.

Who reports adverse events for Sucralfate Oral Suspension (by sex)?

Adverse event reports for Sucralfate Oral Suspension break down by patient sex as follows: Female: 8,236, Male: 4,438, Unknown: 19. This distribution reflects reporting patterns rather than actual risk differences between groups. Reporting rates can be influenced by prescribing patterns, disease demographics, and reporting behavior.

What age groups report the most side effects for Sucralfate Oral Suspension?

The most frequently reported age groups for Sucralfate Oral Suspension adverse events are: age 65: 308 reports, age 64: 281 reports, age 71: 271 reports, age 63: 253 reports, age 66: 251 reports. Age-related reporting patterns can reflect both the demographics of the patient population and potential age-related susceptibility to certain side effects.

Who manufactures Sucralfate Oral Suspension?

The primary manufacturer associated with Sucralfate Oral Suspension adverse event reports is Glenmark Pharmaceuticals Inc., Usa. Multiple manufacturers may produce generic versions of this drug. The manufacturer listed reflects the most frequently reported brand in FDA adverse event data.

What other side effects have been reported for Sucralfate Oral Suspension?

Beyond the most common reactions, other reported adverse events for Sucralfate Oral Suspension include: Off Label Use, Drug Ineffective, Vomiting, Dyspnoea, Chronic Kidney Disease. Less common side effects can still be clinically significant. Patients should report any unusual symptoms to their healthcare provider.

How do I report a side effect from Sucralfate Oral Suspension?

You can report adverse events from Sucralfate Oral Suspension to the FDA through their MedWatch program at www.fda.gov/medwatch, by calling 1-800-FDA-1088, or by completing Form FDA 3500. Healthcare professionals, consumers, and manufacturers can all submit reports. Reporting helps the FDA monitor drug safety after approval.

What is Sucralfate Oral Suspension's safety score and what does it mean?

Sucralfate Oral Suspension has a safety concern score of 65 out of 100 (elevated concern). This score is calculated from the ratio of serious to non-serious adverse events, the diversity of reported reactions, and the overall volume of reports relative to usage. The most common reactions include nausea, diarrhea, and fatigue, indicating gastrointestinal side effects are prevalent.

What are the key safety signals for Sucralfate Oral Suspension?

Key safety signals identified in Sucralfate Oral Suspension's adverse event data include: Chronic kidney disease and renal failure are reported as serious adverse events.. Death and severe infections like sepsis are noted, indicating potential life-threatening risks.. Drug ineffectiveness and off-label use suggest misuse or inefficacy issues.. A variety of neurological and respiratory symptoms are reported, indicating a broad range of potential side effects.. Weight changes, both increase and decrease, are reported, suggesting potential impact on body weight.. These signals are derived from patterns in FDA reports and should be discussed with a healthcare provider for personalized assessment.

Does Sucralfate Oral Suspension interact with other drugs?

Warnings include potential drug interactions and the need for appropriate use to avoid off-label use and drug ineffectiveness. Always inform your healthcare provider about all medications, supplements, and over-the-counter drugs you are taking before starting Sucralfate Oral Suspension.

What should patients know before taking Sucralfate Oral Suspension?

Patients should report any severe or unusual symptoms to their healthcare provider immediately. Follow prescribed dosing instructions and do not use the product for unapproved indications.

Are Sucralfate Oral Suspension side effects well-documented?

Sucralfate Oral Suspension has 33,485 adverse event reports on file with the FDA. Serious reactions such as chronic kidney disease, renal failure, and death are reported, though less frequently. The volume of reports for Sucralfate Oral Suspension reflects both the drug's usage level and the vigilance of the reporting community.

What is the FDA's position on Sucralfate Oral Suspension?

The FDA continues to monitor the safety of SUCRALFATE ORAL SUSPENSION, and healthcare providers should be vigilant about patient safety and proper use. For the most current regulatory information, check the FDA's drug labeling database or consult your pharmacist.

Related Drugs

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Important Disclaimer: This content is generated by AI analysis of FDA adverse event reports and is provided for informational purposes only. It is not medical advice. Adverse event reports submitted to the FDA do not prove that a medication caused the reported side effect. Always consult your healthcare provider before starting, stopping, or changing any medication. If you experience a serious side effect, contact your doctor or call 911 immediately.