TAMSULOSIN HYDROCHLORIDE

65/100 · Elevated

Manufactured by Amneal Pharmaceuticals of New York LLC

Moderate Safety Concerns with Tamsulosin Hydrochloride

41,649 FDA adverse event reports analyzed

Last updated: 2026-05-12

About TAMSULOSIN HYDROCHLORIDE

TAMSULOSIN HYDROCHLORIDE is a medication tracked in the FDA Adverse Event Reporting System (FAERS), manufactured by Amneal Pharmaceuticals of New York LLC. Based on analysis of 41,649 FDA adverse event reports, TAMSULOSIN HYDROCHLORIDE has a safety score of 65 out of 100. This moderate score indicates a notable volume of adverse event reports that patients and providers should be aware of. The most commonly reported adverse reactions for TAMSULOSIN HYDROCHLORIDE include FATIGUE, DYSPNOEA, DIZZINESS, DIARRHOEA, OFF LABEL USE. This page provides a comprehensive breakdown of reported side effects, safety signals, patient demographics, and AI-powered safety analysis for TAMSULOSIN HYDROCHLORIDE.

AI Safety Analysis

Tamsulosin Hydrochloride has a safety concern score of 65 out of 100, placing it in the elevated concern category based on analysis of FDA adverse event data. The FDA has received approximately 41,649 adverse event reports for this medication, which is primarily manufactured by Amneal Pharmaceuticals Of New York Llc.

The most commonly reported adverse events include Fatigue, Dyspnoea, Dizziness. Of classified reports, 76.1% were designated as serious by the FDA, meaning they involved hospitalization, disability, or other significant medical outcomes. Frequent reports of serious adverse events such as falls, respiratory issues, and cardiovascular events.

Significant number of drug interactions and ineffective drug reports. Common side effects include fatigue, dizziness, and gastrointestinal issues. Age distribution shows a higher number of reports in older adults. Sex distribution indicates a higher number of reports for males.

Patients taking Tamsulosin Hydrochloride should monitor for the commonly reported side effects and contact their healthcare provider if they experience any unusual symptoms. Tamsulosin Hydrochloride can interact with other medications, potentially leading to adverse effects. Patients should inform their healthcare provider of all medications they are taking. This analysis is based on voluntary FDA adverse event reports and should not replace professional medical advice.

Safety Score: 65/100

Tamsulosin Hydrochloride received a safety concern score of 65/100 (elevated concern). This is based on a 76.1% serious event ratio across 18,607 classified reports. The score accounts for 41,649 total adverse event reports and 100 distinct reaction types. This elevated score indicates a notable proportion of serious adverse events and warrants careful monitoring.

Top Adverse Reactions

FATIGUE1,417 reports
DYSPNOEA1,332 reports
DIZZINESS1,132 reports
DIARRHOEA1,121 reports
OFF LABEL USE961 reports
DRUG INEFFECTIVE911 reports
HEADACHE883 reports
ASTHENIA841 reports
FALL838 reports
NAUSEA808 reports
COUGH711 reports
MALAISE652 reports
PRURITUS651 reports
ARTHRALGIA644 reports
DEATH637 reports
DECREASED APPETITE600 reports
PYREXIA585 reports
PAIN559 reports
PAIN IN EXTREMITY557 reports
SOMNOLENCE544 reports
INSOMNIA540 reports
RASH535 reports
PNEUMONIA533 reports
HYPOTENSION521 reports
DRUG INTERACTION514 reports
CONDITION AGGRAVATED503 reports
WEIGHT DECREASED478 reports
SYNCOPE468 reports
VOMITING467 reports
PRODUCT DOSE OMISSION ISSUE450 reports
COVID 19427 reports
MYALGIA420 reports
DEPRESSION418 reports
ABDOMINAL PAIN407 reports
PRODUCT USE IN UNAPPROVED INDICATION405 reports
SEPSIS402 reports
BLOOD PRESSURE INCREASED400 reports
CONFUSIONAL STATE399 reports
WHEEZING394 reports
ANXIETY390 reports
ACUTE KIDNEY INJURY389 reports
ASTHMA388 reports
CONSTIPATION385 reports
ATRIAL FIBRILLATION381 reports
HYPERTENSION379 reports
ABDOMINAL PAIN UPPER362 reports
LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES362 reports
URINARY TRACT INFECTION352 reports
EYE PAIN343 reports
HAEMATURIA338 reports
VISION BLURRED337 reports
ANAEMIA334 reports
OBSTRUCTIVE AIRWAYS DISORDER319 reports
PRESYNCOPE315 reports
CHILLS309 reports
TINNITUS303 reports
PRODUCTIVE COUGH302 reports
ABDOMINAL DISCOMFORT299 reports
INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION290 reports
CARDIO RESPIRATORY ARREST289 reports
THERAPEUTIC PRODUCT EFFECT INCOMPLETE285 reports
ALTERED STATE OF CONSCIOUSNESS282 reports
TACHYCARDIA280 reports
BACK PAIN277 reports
HAEMORRHAGIC STROKE270 reports
OEDEMA PERIPHERAL267 reports
GASTROOESOPHAGEAL REFLUX DISEASE263 reports
GAIT DISTURBANCE262 reports
LOSS OF CONSCIOUSNESS260 reports
BENIGN PROSTATIC HYPERPLASIA257 reports
HOT FLUSH257 reports
DYSPNOEA EXERTIONAL252 reports
BRONCHIECTASIS247 reports
HAEMATEMESIS246 reports
PERIPHERAL SWELLING246 reports
FULL BLOOD COUNT ABNORMAL239 reports
COMA238 reports
NASOPHARYNGITIS236 reports
PALPITATIONS235 reports
HEAD DISCOMFORT234 reports
MUSCLE SPASMS233 reports
OCULAR DISCOMFORT233 reports
PULMONARY EMBOLISM233 reports
CEREBROVASCULAR ACCIDENT232 reports
ASCITES229 reports
URINARY RETENTION228 reports
HALLUCINATION224 reports
BLINDNESS221 reports
FEELING ABNORMAL221 reports
DIPLOPIA220 reports
CHRONIC OBSTRUCTIVE PULMONARY DISEASE209 reports
MUSCULAR WEAKNESS207 reports
GENERALISED OEDEMA204 reports
TREMOR204 reports
VERTIGO204 reports
AMAUROSIS FUGAX203 reports
WEIGHT INCREASED200 reports
CHEST PAIN195 reports
RENAL FAILURE193 reports
THROMBOSIS192 reports

Key Safety Signals

  • Falls and syncope are common, indicating potential for falls and dizziness.
  • Respiratory issues like pneumonia and wheezing are reported frequently.
  • Cardiovascular events such as atrial fibrillation and hypertension are notable.
  • Serious adverse events like death and sepsis are reported, though less frequently.
  • Drug interactions and ineffectiveness are significant concerns.

Patient Demographics

Adverse event reports by sex: Male: 15,914, Female: 816, Unknown: 12. The most frequently reported age groups are age 75 (531 reports), age 77 (526 reports), age 74 (521 reports). These demographics reflect reporting patterns and may not represent the full patient population.

Report Outcomes

Out of 18,607 classified reports for TAMSULOSIN HYDROCHLORIDE:

  • Serious: 14,164 reports (76.1%) — includes hospitalization, disability, life-threatening events, or death
  • Non-Serious: 4,443 reports (23.9%)
Serious 76.1%Non-Serious 23.9%

The FDA classifies an adverse event as “serious” if it results in death, hospitalization, disability, congenital anomaly, or requires intervention to prevent permanent damage.

Demographics Breakdown

Reports by Sex

Male15,914 (95.1%)
Female816 (4.9%)
Unknown12 (0.1%)

Reports by Age

Age 75531 reports
Age 77526 reports
Age 74521 reports
Age 80490 reports
Age 72477 reports
Age 70476 reports
Age 78476 reports
Age 71463 reports
Age 76452 reports
Age 73448 reports
Age 79431 reports
Age 65408 reports
Age 68403 reports
Age 67388 reports
Age 82387 reports
Age 84328 reports
Age 69323 reports
Age 66322 reports
Age 85306 reports
Age 64304 reports

Demographics reflect voluntary FDA adverse event reporting patterns and may not represent the full patient population.

Drug Interactions & Warnings

Tamsulosin Hydrochloride can interact with other medications, potentially leading to adverse effects. Patients should inform their healthcare provider of all medications they are taking.

What You Should Know

If you are taking Tamsulosin Hydrochloride, here are important things to know. The most commonly reported side effects include fatigue, dyspnoea, dizziness, diarrhoea, off label use. While many of these may be mild and temporary, you should contact your healthcare provider if any symptoms are severe or persistent. Patients should report any new or worsening symptoms to their healthcare provider immediately. Follow prescribed dosing instructions carefully to avoid drug ineffectiveness or adverse events. If you experience a serious adverse reaction, seek emergency medical attention immediately or call 911. You can report side effects to the FDA's MedWatch program at 1-800-FDA-1088.

Regulatory Context

The FDA continues to monitor the safety of Tamsulosin Hydrochloride. Healthcare providers should be vigilant in monitoring patients for serious adverse events and drug interactions.

Frequently Asked Questions

How many adverse event reports has the FDA received for Tamsulosin Hydrochloride?

The FDA has received approximately 41,649 adverse event reports associated with Tamsulosin Hydrochloride. These reports come from healthcare professionals, consumers, and manufacturers through the FDA Adverse Event Reporting System (FAERS). Note that the number of reports does not directly indicate the frequency of side effects, as adverse events are voluntarily reported and may be underrepresented.

What are the most commonly reported side effects of Tamsulosin Hydrochloride?

The most frequently reported adverse events for Tamsulosin Hydrochloride include Fatigue, Dyspnoea, Dizziness, Diarrhoea, Off Label Use. By volume, the top reported reactions are: Fatigue (1,417 reports), Dyspnoea (1,332 reports), Dizziness (1,132 reports). These figures reflect FDA adverse event reports and may not represent the true incidence rate of these side effects in all patients taking Tamsulosin Hydrochloride.

What percentage of Tamsulosin Hydrochloride adverse event reports are serious?

Out of 18,607 classified reports, 14,164 (76.1%) were classified as serious and 4,443 as non-serious. The FDA classifies an event as "serious" if it results in death, hospitalization, disability, or other medically significant outcomes. A higher serious-event ratio warrants closer attention but does not necessarily mean the drug is unsafe.

Who reports adverse events for Tamsulosin Hydrochloride (by sex)?

Adverse event reports for Tamsulosin Hydrochloride break down by patient sex as follows: Male: 15,914, Female: 816, Unknown: 12. This distribution reflects reporting patterns rather than actual risk differences between groups. Reporting rates can be influenced by prescribing patterns, disease demographics, and reporting behavior.

What age groups report the most side effects for Tamsulosin Hydrochloride?

The most frequently reported age groups for Tamsulosin Hydrochloride adverse events are: age 75: 531 reports, age 77: 526 reports, age 74: 521 reports, age 80: 490 reports, age 72: 477 reports. Age-related reporting patterns can reflect both the demographics of the patient population and potential age-related susceptibility to certain side effects.

Who manufactures Tamsulosin Hydrochloride?

The primary manufacturer associated with Tamsulosin Hydrochloride adverse event reports is Amneal Pharmaceuticals Of New York Llc. Multiple manufacturers may produce generic versions of this drug. The manufacturer listed reflects the most frequently reported brand in FDA adverse event data.

What other side effects have been reported for Tamsulosin Hydrochloride?

Beyond the most common reactions, other reported adverse events for Tamsulosin Hydrochloride include: Drug Ineffective, Headache, Asthenia, Fall, Nausea. Less common side effects can still be clinically significant. Patients should report any unusual symptoms to their healthcare provider.

How do I report a side effect from Tamsulosin Hydrochloride?

You can report adverse events from Tamsulosin Hydrochloride to the FDA through their MedWatch program at www.fda.gov/medwatch, by calling 1-800-FDA-1088, or by completing Form FDA 3500. Healthcare professionals, consumers, and manufacturers can all submit reports. Reporting helps the FDA monitor drug safety after approval.

What is Tamsulosin Hydrochloride's safety score and what does it mean?

Tamsulosin Hydrochloride has a safety concern score of 65 out of 100 (elevated concern). This score is calculated from the ratio of serious to non-serious adverse events, the diversity of reported reactions, and the overall volume of reports relative to usage. Frequent reports of serious adverse events such as falls, respiratory issues, and cardiovascular events.

What are the key safety signals for Tamsulosin Hydrochloride?

Key safety signals identified in Tamsulosin Hydrochloride's adverse event data include: Falls and syncope are common, indicating potential for falls and dizziness.. Respiratory issues like pneumonia and wheezing are reported frequently.. Cardiovascular events such as atrial fibrillation and hypertension are notable.. Serious adverse events like death and sepsis are reported, though less frequently.. Drug interactions and ineffectiveness are significant concerns.. These signals are derived from patterns in FDA reports and should be discussed with a healthcare provider for personalized assessment.

Does Tamsulosin Hydrochloride interact with other drugs?

Tamsulosin Hydrochloride can interact with other medications, potentially leading to adverse effects. Patients should inform their healthcare provider of all medications they are taking. Always inform your healthcare provider about all medications, supplements, and over-the-counter drugs you are taking before starting Tamsulosin Hydrochloride.

What should patients know before taking Tamsulosin Hydrochloride?

Patients should report any new or worsening symptoms to their healthcare provider immediately. Follow prescribed dosing instructions carefully to avoid drug ineffectiveness or adverse events.

Are Tamsulosin Hydrochloride side effects well-documented?

Tamsulosin Hydrochloride has 41,649 adverse event reports on file with the FDA. Significant number of drug interactions and ineffective drug reports. The volume of reports for Tamsulosin Hydrochloride reflects both the drug's usage level and the vigilance of the reporting community.

What is the FDA's position on Tamsulosin Hydrochloride?

The FDA continues to monitor the safety of Tamsulosin Hydrochloride. Healthcare providers should be vigilant in monitoring patients for serious adverse events and drug interactions. For the most current regulatory information, check the FDA's drug labeling database or consult your pharmacist.

Related Drugs

Drugs related to TAMSULOSIN HYDROCHLORIDE based on therapeutic use, drug class, or shared indications:

Amneal Pharmaceuticals of New York LLCOther manufacturersHealthcare providersPharmacistsRegulatory agencies
Important Disclaimer: This content is generated by AI analysis of FDA adverse event reports and is provided for informational purposes only. It is not medical advice. Adverse event reports submitted to the FDA do not prove that a medication caused the reported side effect. Always consult your healthcare provider before starting, stopping, or changing any medication. If you experience a serious side effect, contact your doctor or call 911 immediately.