Trulicity

N/A

Manufactured by Eli Lilly and Company

154,428 FDA adverse event reports analyzed

Last updated: 2026-05-19

About Trulicity

Trulicity is a medication tracked in the FDA Adverse Event Reporting System (FAERS), manufactured by Eli Lilly and Company. The most commonly reported adverse reactions for Trulicity include NAUSEA, INJECTION SITE PAIN, BLOOD GLUCOSE INCREASED, DIARRHOEA, VOMITING. This page provides a comprehensive breakdown of reported side effects, safety signals, patient demographics, and AI-powered safety analysis for Trulicity.

Top Adverse Reactions

NAUSEA10,199 reports
INJECTION SITE PAIN9,872 reports
BLOOD GLUCOSE INCREASED9,831 reports
DIARRHOEA5,948 reports
VOMITING5,608 reports
INCORRECT DOSE ADMINISTERED5,535 reports
INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION3,831 reports
DRUG INEFFECTIVE3,602 reports
WEIGHT DECREASED3,390 reports
DECREASED APPETITE3,227 reports
INJECTION SITE HAEMORRHAGE3,145 reports
EXTRA DOSE ADMINISTERED3,140 reports
GLYCOSYLATED HAEMOGLOBIN INCREASED2,932 reports
FATIGUE2,441 reports
ABDOMINAL PAIN UPPER2,428 reports
ACCIDENTAL UNDERDOSE2,360 reports
PRODUCT DOSE OMISSION ISSUE2,252 reports
CONSTIPATION2,246 reports
ABDOMINAL PAIN2,211 reports
MALAISE2,062 reports
INJECTION SITE BRUISING1,930 reports
ACCIDENTAL OVERDOSE1,872 reports
DIZZINESS1,859 reports
BLOOD GLUCOSE DECREASED1,834 reports
OFF LABEL USE1,797 reports
ABDOMINAL DISCOMFORT1,761 reports
HEADACHE1,715 reports
INJECTION SITE ERYTHEMA1,634 reports
IMPAIRED GASTRIC EMPTYING1,593 reports
PANCREATITIS1,512 reports
DYSPEPSIA1,484 reports
INJECTION SITE MASS1,413 reports
ILLNESS1,406 reports
VISUAL IMPAIRMENT1,374 reports
DRUG DOSE OMISSION1,353 reports
ASTHENIA1,315 reports
FEELING ABNORMAL1,315 reports
WEIGHT INCREASED1,296 reports
INJECTION SITE PRURITUS1,254 reports
PAIN1,178 reports
DEHYDRATION1,174 reports
ABDOMINAL DISTENSION1,152 reports
ERUCTATION1,094 reports
UNDERDOSE1,075 reports
BLOOD GLUCOSE ABNORMAL1,011 reports
DYSPNOEA963 reports
OVERDOSE953 reports
RASH890 reports
FALL889 reports
COVID 19850 reports
FLATULENCE836 reports
PRURITUS814 reports
INJECTION SITE SWELLING809 reports
GASTROINTESTINAL DISORDER782 reports
ACUTE KIDNEY INJURY750 reports
DEATH744 reports
PRODUCT DOSE OMISSION728 reports
GASTROOESOPHAGEAL REFLUX DISEASE707 reports
ANXIETY673 reports
PAIN IN EXTREMITY665 reports
MEMORY IMPAIRMENT662 reports
ARTHRALGIA657 reports
WRONG TECHNIQUE IN PRODUCT USAGE PROCESS657 reports
PRODUCT STORAGE ERROR653 reports
BACK PAIN629 reports
VISION BLURRED629 reports
CEREBROVASCULAR ACCIDENT569 reports
DRUG HYPERSENSITIVITY550 reports
HYPOGLYCAEMIA547 reports
DEPRESSION546 reports
GAIT DISTURBANCE541 reports
COUGH538 reports
INJECTION SITE RASH521 reports
INJURY ASSOCIATED WITH DEVICE508 reports
GASTROINTESTINAL HYPOMOTILITY506 reports
PRODUCT ADMINISTERED AT INAPPROPRIATE SITE499 reports
TREMOR499 reports
URINARY TRACT INFECTION493 reports
INAPPROPRIATE SCHEDULE OF DRUG ADMINISTRATION482 reports
DIABETES MELLITUS INADEQUATE CONTROL476 reports
INJECTION SITE URTICARIA473 reports
FEEDING DISORDER471 reports
INSOMNIA470 reports
BLOOD PRESSURE INCREASED469 reports
MUSCLE SPASMS469 reports
HYPOACUSIS455 reports
DIABETIC KETOACIDOSIS437 reports
SOMNOLENCE432 reports
HYPERSENSITIVITY430 reports
PNEUMONIA424 reports
HYPERTENSION423 reports
PERIPHERAL SWELLING422 reports
ALOPECIA421 reports
CATARACT414 reports
NASOPHARYNGITIS413 reports
URTICARIA404 reports
MYOCARDIAL INFARCTION387 reports
HYPERHIDROSIS383 reports
INJECTION SITE DISCOMFORT382 reports
RENAL FAILURE373 reports

Report Outcomes

Out of 86,757 classified reports for Trulicity:

  • Serious: 22,179 reports (25.6%) — includes hospitalization, disability, life-threatening events, or death
  • Non-Serious: 64,578 reports (74.4%)
Serious 25.6%Non-Serious 74.4%

The FDA classifies an adverse event as “serious” if it results in death, hospitalization, disability, congenital anomaly, or requires intervention to prevent permanent damage.

Demographics Breakdown

Reports by Sex

Female45,048 (57.9%)
Male32,779 (42.1%)
Unknown11 (0.0%)

Reports by Age

Age 651,475 reports
Age 601,309 reports
Age 621,267 reports
Age 661,259 reports
Age 641,240 reports
Age 701,230 reports
Age 631,223 reports
Age 611,214 reports
Age 691,212 reports
Age 551,204 reports
Age 681,177 reports
Age 671,164 reports
Age 591,114 reports
Age 581,106 reports
Age 711,066 reports
Age 571,006 reports
Age 72995 reports
Age 73948 reports
Age 75936 reports
Age 56913 reports

Demographics reflect voluntary FDA adverse event reporting patterns and may not represent the full patient population.

Frequently Asked Questions

How many FDA adverse event reports are associated with Trulicity?

This profile reflects 154,428 FDA FAERS reports that mention Trulicity. Reporting is voluntary and does not prove that the drug caused any listed event.

Which adverse reactions are most often listed for Trulicity?

Frequently reported terms in FAERS include NAUSEA, INJECTION SITE PAIN, BLOOD GLUCOSE INCREASED, DIARRHOEA, VOMITING, INCORRECT DOSE ADMINISTERED. Rankings reflect reporting volume in this dataset, not confirmed side effect rates in the general population.

Who manufactures Trulicity?

Labeling and FAERS entries often list Eli Lilly and Company in connection with Trulicity. Always verify the specific product and NDC with your pharmacist.

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Drugs Also Linked to NAUSEA

The following drugs share commonly reported adverse reactions with Trulicity:

0XYGEN (75/100)ABACAVIR SULFATE (85/100)ABALOPARATIDE (35/100)ABEMACICLIB (78/100)Abilify MaintenaABIRATERONE ACETATE (72/100)ACALABRUTINIB (78/100)ACETAMINOPHEN (35/100)ACETAMINOPHEN 325 MG (65/100)ACETAMINOPHEN 325MG (65/100)ACETAMINOPHEN 500 MG (65/100)ACETAMINOPHEN 500MG (85/100)

View all drugs reporting NAUSEA →

Explore More

Safety RankingsSearch All DrugsCompare DrugsEli Lilly and Company PortfolioNAUSEA in Other DrugsINJECTION SITE PAIN in Other DrugsBLOOD GLUCOSE INCREASED in Other Drugs
Important Disclaimer: This content is generated by AI analysis of FDA adverse event reports and is provided for informational purposes only. It is not medical advice. Adverse event reports submitted to the FDA do not prove that a medication caused the reported side effect. Always consult your healthcare provider before starting, stopping, or changing any medication. If you experience a serious side effect, contact your doctor or call 911 immediately.