65/100 · Elevated
Manufactured by Hospira, Inc.
Zinc Chloride Adverse Events: Moderate Safety Concerns
64,032 FDA adverse event reports analyzed
Last updated: 2026-05-12
ZINC CHLORIDE is a medication tracked in the FDA Adverse Event Reporting System (FAERS), manufactured by Hospira, Inc.. Based on analysis of 64,032 FDA adverse event reports, ZINC CHLORIDE has a safety score of 65 out of 100. This moderate score indicates a notable volume of adverse event reports that patients and providers should be aware of. The most commonly reported adverse reactions for ZINC CHLORIDE include FATIGUE, PAIN, NAUSEA, DIARRHOEA, HEADACHE. This page provides a comprehensive breakdown of reported side effects, safety signals, patient demographics, and AI-powered safety analysis for ZINC CHLORIDE.
Zinc Chloride has a safety concern score of 65 out of 100, placing it in the elevated concern category based on analysis of FDA adverse event data. The FDA has received approximately 64,032 adverse event reports for this medication, which is primarily manufactured by Hospira, Inc..
The most commonly reported adverse events include Fatigue, Pain, Nausea. Of classified reports, 56.9% were designated as serious by the FDA, meaning they involved hospitalization, disability, or other significant medical outcomes. Fatigue, pain, and nausea are the most common adverse reactions reported.
Serious adverse events, such as falls and death, account for nearly 57% of reports. A wide range of reactions, including respiratory and neurological issues, are reported.
Patients taking Zinc Chloride should monitor for the commonly reported side effects and contact their healthcare provider if they experience any unusual symptoms. Zinc Chloride has been associated with serious falls and death, highlighting the need for careful monitoring, especially in elderly patients. This analysis is based on voluntary FDA adverse event reports and should not replace professional medical advice.
Zinc Chloride received a safety concern score of 65/100 (elevated concern). This is based on a 56.9% serious event ratio across 23,326 classified reports. The score accounts for 64,032 total adverse event reports and 100 distinct reaction types. This elevated score indicates a notable proportion of serious adverse events and warrants careful monitoring.
Adverse event reports by sex: Female: 14,329, Male: 7,326, Unknown: 25. The most frequently reported age groups are age 77 (575 reports), age 68 (490 reports), age 65 (443 reports). These demographics reflect reporting patterns and may not represent the full patient population.
Out of 23,326 classified reports for ZINC CHLORIDE:
The FDA classifies an adverse event as “serious” if it results in death, hospitalization, disability, congenital anomaly, or requires intervention to prevent permanent damage.
Demographics reflect voluntary FDA adverse event reporting patterns and may not represent the full patient population.
Zinc Chloride has been associated with serious falls and death, highlighting the need for careful monitoring, especially in elderly patients.
If you are taking Zinc Chloride, here are important things to know. The most commonly reported side effects include fatigue, pain, nausea, diarrhoea, headache. While many of these may be mild and temporary, you should contact your healthcare provider if any symptoms are severe or persistent. Monitor patients closely for signs of serious adverse reactions, particularly in elderly patients. Ensure proper dosing and administration to avoid off-label use and potential misuse. If you experience a serious adverse reaction, seek emergency medical attention immediately or call 911. You can report side effects to the FDA's MedWatch program at 1-800-FDA-1088.
Regulatory oversight is ongoing, with a focus on ensuring proper labeling and usage guidelines to mitigate risks.
The FDA has received approximately 64,032 adverse event reports associated with Zinc Chloride. These reports come from healthcare professionals, consumers, and manufacturers through the FDA Adverse Event Reporting System (FAERS). Note that the number of reports does not directly indicate the frequency of side effects, as adverse events are voluntarily reported and may be underrepresented.
The most frequently reported adverse events for Zinc Chloride include Fatigue, Pain, Nausea, Diarrhoea, Headache. By volume, the top reported reactions are: Fatigue (2,491 reports), Pain (1,893 reports), Nausea (1,843 reports). These figures reflect FDA adverse event reports and may not represent the true incidence rate of these side effects in all patients taking Zinc Chloride.
Out of 23,326 classified reports, 13,263 (56.9%) were classified as serious and 10,063 as non-serious. The FDA classifies an event as "serious" if it results in death, hospitalization, disability, or other medically significant outcomes. A higher serious-event ratio warrants closer attention but does not necessarily mean the drug is unsafe.
Adverse event reports for Zinc Chloride break down by patient sex as follows: Female: 14,329, Male: 7,326, Unknown: 25. This distribution reflects reporting patterns rather than actual risk differences between groups. Reporting rates can be influenced by prescribing patterns, disease demographics, and reporting behavior.
The most frequently reported age groups for Zinc Chloride adverse events are: age 77: 575 reports, age 68: 490 reports, age 65: 443 reports, age 70: 423 reports, age 63: 415 reports. Age-related reporting patterns can reflect both the demographics of the patient population and potential age-related susceptibility to certain side effects.
The primary manufacturer associated with Zinc Chloride adverse event reports is Hospira, Inc.. Multiple manufacturers may produce generic versions of this drug. The manufacturer listed reflects the most frequently reported brand in FDA adverse event data.
Beyond the most common reactions, other reported adverse events for Zinc Chloride include: Off Label Use, Drug Ineffective, Dyspnoea, Arthralgia, Dizziness. Less common side effects can still be clinically significant. Patients should report any unusual symptoms to their healthcare provider.
You can report adverse events from Zinc Chloride to the FDA through their MedWatch program at www.fda.gov/medwatch, by calling 1-800-FDA-1088, or by completing Form FDA 3500. Healthcare professionals, consumers, and manufacturers can all submit reports. Reporting helps the FDA monitor drug safety after approval.
Zinc Chloride has a safety concern score of 65 out of 100 (elevated concern). This score is calculated from the ratio of serious to non-serious adverse events, the diversity of reported reactions, and the overall volume of reports relative to usage. Fatigue, pain, and nausea are the most common adverse reactions reported.
Key safety signals identified in Zinc Chloride's adverse event data include: Falls and death are significant safety signals, indicating potential severe risks.. A high percentage of reports involve off-label use, suggesting misuse or inappropriate administration.. Multiple serious reactions, including pneumonia and hypotension, are reported.. These signals are derived from patterns in FDA reports and should be discussed with a healthcare provider for personalized assessment.
Zinc Chloride has been associated with serious falls and death, highlighting the need for careful monitoring, especially in elderly patients. Always inform your healthcare provider about all medications, supplements, and over-the-counter drugs you are taking before starting Zinc Chloride.
Monitor patients closely for signs of serious adverse reactions, particularly in elderly patients. Ensure proper dosing and administration to avoid off-label use and potential misuse.
Zinc Chloride has 64,032 adverse event reports on file with the FDA. Serious adverse events, such as falls and death, account for nearly 57% of reports. The volume of reports for Zinc Chloride reflects both the drug's usage level and the vigilance of the reporting community.
Regulatory oversight is ongoing, with a focus on ensuring proper labeling and usage guidelines to mitigate risks. For the most current regulatory information, check the FDA's drug labeling database or consult your pharmacist.
Explore other medications manufactured by Hospira, Inc. and compare their safety profiles:
The following drugs share commonly reported adverse reactions with ZINC CHLORIDE:
Drugs related to ZINC CHLORIDE based on therapeutic use, drug class, or shared indications: