Atorvastatin

38/100 · Moderate

Manufactured by Pfizer

Leading cholesterol drug with muscle pain as the primary concern

167,200 FDA adverse event reports analyzed

About Atorvastatin

Atorvastatin is a medication tracked in the FDA Adverse Event Reporting System (FAERS), manufactured by Pfizer. Based on analysis of 167,200 FDA adverse event reports, Atorvastatin has a safety score of 38 out of 100. This lower score reflects a significant number of adverse event reports, suggesting that patients should discuss potential risks carefully with their healthcare provider. The most commonly reported adverse reactions for Atorvastatin include Myalgia, Liver Enzyme Elevation, Rhabdomyolysis, Headache. This page provides a comprehensive breakdown of reported side effects, safety signals, patient demographics, and AI-powered safety analysis for Atorvastatin.

AI Safety Analysis

Atorvastatin (brand name Lipitor) is the most prescribed statin worldwide for cholesterol management. Muscle-related complaints are the most frequently reported adverse events, ranging from mild myalgia to rare but serious rhabdomyolysis.

Liver enzyme elevations require monitoring but rarely lead to significant liver damage. The drug's safety profile is well-characterized after decades of widespread use.

Top Adverse Reactions

Myalgia28,400 reports
Liver Enzyme Elevation12,100 reports
Rhabdomyolysis3,200 reports
Headache9,800 reports

Frequently Asked Questions

Can Atorvastatin cause muscle pain?

Yes, muscle pain (myalgia) is the most commonly reported side effect. It ranges from mild discomfort to rarely, serious muscle breakdown. Report any unexplained muscle pain to your doctor.

How many FDA adverse event reports are associated with Atorvastatin?

This profile reflects 167,200 FDA FAERS reports that mention Atorvastatin. Reporting is voluntary and does not prove that the drug caused any listed event.

Which adverse reactions are most often listed for Atorvastatin?

Frequently reported terms in FAERS include Myalgia, Liver Enzyme Elevation, Rhabdomyolysis, Headache. Rankings reflect reporting volume in this dataset, not confirmed side effect rates in the general population.

How should I interpret Atorvastatin's safety score?

Atorvastatin has a score of 38 out of 100 in our model (higher suggests more reporting-related concern). Use it alongside the official prescribing information and advice from your clinician.

Who manufactures Atorvastatin?

Labeling and FAERS entries often list Pfizer in connection with Atorvastatin. Always verify the specific product and NDC with your pharmacist.

Related Drugs

Drugs related to Atorvastatin based on therapeutic use, drug class, or shared indications:

RosuvastatinSimvastatinPravastatinEzetimibe
Important Disclaimer: This content is generated by AI analysis of FDA adverse event reports and is provided for informational purposes only. It is not medical advice. Adverse event reports submitted to the FDA do not prove that a medication caused the reported side effect. Always consult your healthcare provider before starting, stopping, or changing any medication. If you experience a serious side effect, contact your doctor or call 911 immediately.