CABERGOLINE

78/100 · Elevated

Manufactured by Amneal Pharmaceuticals NY LLC

CABERGOLINE Adverse Events: High Serious Reaction Rate and Diverse Safety Profile

10,212 FDA adverse event reports analyzed

Last updated: 2026-05-12

About CABERGOLINE

CABERGOLINE is a medication tracked in the FDA Adverse Event Reporting System (FAERS), manufactured by Amneal Pharmaceuticals NY LLC. Based on analysis of 10,212 FDA adverse event reports, CABERGOLINE has a safety score of 78 out of 100. This score indicates a relatively favorable safety profile, with fewer or less severe adverse events compared to many other tracked medications. The most commonly reported adverse reactions for CABERGOLINE include DRUG INEFFECTIVE, OFF LABEL USE, HEADACHE, FATIGUE, NAUSEA. This page provides a comprehensive breakdown of reported side effects, safety signals, patient demographics, and AI-powered safety analysis for CABERGOLINE.

AI Safety Analysis

Cabergoline has a safety concern score of 78 out of 100, placing it in the high concern category based on analysis of FDA adverse event data. The FDA has received approximately 10,212 adverse event reports for this medication, which is primarily manufactured by Amneal Pharmaceuticals Ny Llc.

The most commonly reported adverse events include Drug Ineffective, Off Label Use, Headache. Of classified reports, 81.9% were designated as serious by the FDA, meaning they involved hospitalization, disability, or other significant medical outcomes. High percentage of serious adverse events (81.9%) indicates significant safety concerns.

Diverse range of reactions suggests potential for multiple side effects. Common reactions include headache, fatigue, and nausea, with some reports of serious cardiovascular and respiratory issues.

Patients taking Cabergoline should monitor for the commonly reported side effects and contact their healthcare provider if they experience any unusual symptoms. CABERGOLINE has warnings for drug interactions and misuse, including potential for increased blood pressure and respiratory issues. This analysis is based on voluntary FDA adverse event reports and should not replace professional medical advice.

Safety Score: 78/100

Cabergoline received a safety concern score of 78/100 (high concern). This is based on a 81.9% serious event ratio across 4,669 classified reports. The score accounts for 10,212 total adverse event reports and 100 distinct reaction types. This high score reflects a significant proportion of serious adverse events in the reporting data.

Top Adverse Reactions

DRUG INEFFECTIVE390 reports
OFF LABEL USE351 reports
HEADACHE319 reports
FATIGUE275 reports
NAUSEA274 reports
DIZZINESS224 reports
MALAISE209 reports
PAIN195 reports
DIARRHOEA175 reports
CONDITION AGGRAVATED170 reports
ANXIETY158 reports
RASH155 reports
VOMITING154 reports
PRODUCT DOSE OMISSION ISSUE152 reports
FALL150 reports
ABDOMINAL DISCOMFORT148 reports
DRUG INTERACTION142 reports
WEIGHT DECREASED137 reports
ASTHENIA133 reports
ARTHRALGIA128 reports
DYSPNOEA125 reports
BLOOD PRESSURE INCREASED121 reports
ARTHROPATHY119 reports
DRUG ABUSE114 reports
PAIN IN EXTREMITY113 reports
ABDOMINAL PAIN UPPER109 reports
GAIT DISTURBANCE109 reports
INTENTIONAL PRODUCT MISUSE104 reports
ABDOMINAL PAIN103 reports
FEELING ABNORMAL103 reports
HYPERTENSION103 reports
LOWER RESPIRATORY TRACT INFECTION103 reports
MITRAL VALVE INCOMPETENCE101 reports
OVERDOSE101 reports
PULMONARY PAIN100 reports
PERIPHERAL SWELLING99 reports
DECREASED APPETITE98 reports
DEPRESSION98 reports
INJECTION SITE PAIN98 reports
WEIGHT INCREASED92 reports
CEREBROSPINAL FLUID LEAKAGE91 reports
COVID 1990 reports
AORTIC VALVE INCOMPETENCE89 reports
MATERNAL EXPOSURE DURING PREGNANCY89 reports
INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION88 reports
INSOMNIA88 reports
INSULIN LIKE GROWTH FACTOR INCREASED85 reports
SOMNOLENCE85 reports
MEMORY IMPAIRMENT83 reports
BACK PAIN81 reports
CONSTIPATION81 reports
COUGH79 reports
PRURITUS78 reports
BLOOD GROWTH HORMONE INCREASED77 reports
CHEST PAIN77 reports
DRUG INTOLERANCE77 reports
NEOPLASM PROGRESSION77 reports
PYREXIA77 reports
BLOOD GLUCOSE INCREASED76 reports
BLOOD PROLACTIN INCREASED76 reports
KNEE ARTHROPLASTY76 reports
PLEURAL EFFUSION76 reports
PRODUCT USE IN UNAPPROVED INDICATION76 reports
CONFUSIONAL STATE75 reports
DIABETES MELLITUS74 reports
CHOLELITHIASIS71 reports
OEDEMA PERIPHERAL69 reports
HALLUCINATION68 reports
HYPERHIDROSIS68 reports
HYPOAESTHESIA67 reports
ALOPECIA65 reports
BALANCE DISORDER64 reports
PARAESTHESIA64 reports
ANAEMIA63 reports
CARDIAC VALVE DISEASE63 reports
DISEASE PROGRESSION63 reports
DRUG RESISTANCE61 reports
VISUAL IMPAIRMENT61 reports
MUSCLE SPASMS60 reports
HYPOTENSION59 reports
OBESITY59 reports
ERYTHEMA58 reports
INFLAMMATION58 reports
MUSCULAR WEAKNESS57 reports
CARDIAC FAILURE56 reports
NASOPHARYNGITIS56 reports
TREMOR56 reports
ILLNESS55 reports
PNEUMONIA55 reports
HYPOGLYCAEMIA54 reports
MYALGIA54 reports
BLOOD PRESSURE SYSTOLIC INCREASED53 reports
HYPERGLYCAEMIA53 reports
PATHOLOGICAL GAMBLING52 reports
TRICUSPID VALVE INCOMPETENCE52 reports
BLOOD PRESSURE DECREASED50 reports
HYPERSENSITIVITY50 reports
DEPRESSED MOOD49 reports
LUNG NEOPLASM MALIGNANT48 reports
SLEEP APNOEA SYNDROME48 reports

Key Safety Signals

  • High number of serious adverse events (3822 out of 4669, 81.9%)
  • Multiple cardiovascular and respiratory issues reported, including hypertension, dyspnea, and pneumonia
  • Significant drug interactions and misuse reported, with 142 cases of drug interaction and 104 cases of overdose

Patient Demographics

Adverse event reports by sex: Female: 2,447, Male: 1,693, Unknown: 32. The most frequently reported age groups are age 56 (115 reports), age 68 (99 reports), age 65 (79 reports). These demographics reflect reporting patterns and may not represent the full patient population.

Report Outcomes

Out of 4,669 classified reports for CABERGOLINE:

  • Serious: 3,822 reports (81.9%) — includes hospitalization, disability, life-threatening events, or death
  • Non-Serious: 847 reports (18.1%)
Serious 81.9%Non-Serious 18.1%

The FDA classifies an adverse event as “serious” if it results in death, hospitalization, disability, congenital anomaly, or requires intervention to prevent permanent damage.

Demographics Breakdown

Reports by Sex

Female2,447 (58.7%)
Male1,693 (40.6%)
Unknown32 (0.8%)

Reports by Age

Age 56115 reports
Age 6899 reports
Age 6579 reports
Age 3874 reports
Age 3472 reports
Age 3568 reports
Age 4268 reports
Age 6968 reports
Age 3366 reports
Age 4564 reports
Age 6163 reports
Age 4061 reports
Age 2760 reports
Age 2960 reports
Age 3260 reports
Age 5460 reports
Age 5059 reports
Age 3658 reports
Age 4858 reports
Age 4957 reports

Demographics reflect voluntary FDA adverse event reporting patterns and may not represent the full patient population.

Drug Interactions & Warnings

CABERGOLINE has warnings for drug interactions and misuse, including potential for increased blood pressure and respiratory issues.

What You Should Know

If you are taking Cabergoline, here are important things to know. The most commonly reported side effects include drug ineffective, off label use, headache, fatigue, nausea. While many of these may be mild and temporary, you should contact your healthcare provider if any symptoms are severe or persistent. Patients should report any serious side effects to their healthcare provider immediately. Follow prescribed dosing instructions and avoid misuse or overdose. If you experience a serious adverse reaction, seek emergency medical attention immediately or call 911. You can report side effects to the FDA's MedWatch program at 1-800-FDA-1088.

Regulatory Context

The FDA closely monitors CABERGOLINE for serious adverse events, particularly in patients with pre-existing cardiovascular or respiratory conditions.

Frequently Asked Questions

How many adverse event reports has the FDA received for Cabergoline?

The FDA has received approximately 10,212 adverse event reports associated with Cabergoline. These reports come from healthcare professionals, consumers, and manufacturers through the FDA Adverse Event Reporting System (FAERS). Note that the number of reports does not directly indicate the frequency of side effects, as adverse events are voluntarily reported and may be underrepresented.

What are the most commonly reported side effects of Cabergoline?

The most frequently reported adverse events for Cabergoline include Drug Ineffective, Off Label Use, Headache, Fatigue, Nausea. By volume, the top reported reactions are: Drug Ineffective (390 reports), Off Label Use (351 reports), Headache (319 reports). These figures reflect FDA adverse event reports and may not represent the true incidence rate of these side effects in all patients taking Cabergoline.

What percentage of Cabergoline adverse event reports are serious?

Out of 4,669 classified reports, 3,822 (81.9%) were classified as serious and 847 as non-serious. The FDA classifies an event as "serious" if it results in death, hospitalization, disability, or other medically significant outcomes. A higher serious-event ratio warrants closer attention but does not necessarily mean the drug is unsafe.

Who reports adverse events for Cabergoline (by sex)?

Adverse event reports for Cabergoline break down by patient sex as follows: Female: 2,447, Male: 1,693, Unknown: 32. This distribution reflects reporting patterns rather than actual risk differences between groups. Reporting rates can be influenced by prescribing patterns, disease demographics, and reporting behavior.

What age groups report the most side effects for Cabergoline?

The most frequently reported age groups for Cabergoline adverse events are: age 56: 115 reports, age 68: 99 reports, age 65: 79 reports, age 38: 74 reports, age 34: 72 reports. Age-related reporting patterns can reflect both the demographics of the patient population and potential age-related susceptibility to certain side effects.

Who manufactures Cabergoline?

The primary manufacturer associated with Cabergoline adverse event reports is Amneal Pharmaceuticals Ny Llc. Multiple manufacturers may produce generic versions of this drug. The manufacturer listed reflects the most frequently reported brand in FDA adverse event data.

What other side effects have been reported for Cabergoline?

Beyond the most common reactions, other reported adverse events for Cabergoline include: Dizziness, Malaise, Pain, Diarrhoea, Condition Aggravated. Less common side effects can still be clinically significant. Patients should report any unusual symptoms to their healthcare provider.

How do I report a side effect from Cabergoline?

You can report adverse events from Cabergoline to the FDA through their MedWatch program at www.fda.gov/medwatch, by calling 1-800-FDA-1088, or by completing Form FDA 3500. Healthcare professionals, consumers, and manufacturers can all submit reports. Reporting helps the FDA monitor drug safety after approval.

What is Cabergoline's safety score and what does it mean?

Cabergoline has a safety concern score of 78 out of 100 (high concern). This score is calculated from the ratio of serious to non-serious adverse events, the diversity of reported reactions, and the overall volume of reports relative to usage. High percentage of serious adverse events (81.9%) indicates significant safety concerns.

What are the key safety signals for Cabergoline?

Key safety signals identified in Cabergoline's adverse event data include: High number of serious adverse events (3822 out of 4669, 81.9%). Multiple cardiovascular and respiratory issues reported, including hypertension, dyspnea, and pneumonia. Significant drug interactions and misuse reported, with 142 cases of drug interaction and 104 cases of overdose. These signals are derived from patterns in FDA reports and should be discussed with a healthcare provider for personalized assessment.

Does Cabergoline interact with other drugs?

CABERGOLINE has warnings for drug interactions and misuse, including potential for increased blood pressure and respiratory issues. Always inform your healthcare provider about all medications, supplements, and over-the-counter drugs you are taking before starting Cabergoline.

What should patients know before taking Cabergoline?

Patients should report any serious side effects to their healthcare provider immediately. Follow prescribed dosing instructions and avoid misuse or overdose.

Are Cabergoline side effects well-documented?

Cabergoline has 10,212 adverse event reports on file with the FDA. Diverse range of reactions suggests potential for multiple side effects. The volume of reports for Cabergoline reflects both the drug's usage level and the vigilance of the reporting community.

What is the FDA's position on Cabergoline?

The FDA closely monitors CABERGOLINE for serious adverse events, particularly in patients with pre-existing cardiovascular or respiratory conditions. For the most current regulatory information, check the FDA's drug labeling database or consult your pharmacist.

Related Drugs

Drugs related to CABERGOLINE based on therapeutic use, drug class, or shared indications:

Amneal Pharmaceuticals NY LLCNovartis Pharmaceuticals CorporationSandoz Inc.Alkermes plcMylan Pharmaceuticals Inc.
Important Disclaimer: This content is generated by AI analysis of FDA adverse event reports and is provided for informational purposes only. It is not medical advice. Adverse event reports submitted to the FDA do not prove that a medication caused the reported side effect. Always consult your healthcare provider before starting, stopping, or changing any medication. If you experience a serious side effect, contact your doctor or call 911 immediately.