NORETHINDRONE ACETATE AND ETHINYL ESTRADIOL AND FERROUS FUMARATE

65/100 · Elevated

Manufactured by Teva Pharmaceuticals USA, Inc.

Safety Profile for NORETHINDRONE ACETATE AND ETHINYL ESTRADIOL AND FERROUS FUMARATE

4,509 FDA adverse event reports analyzed

Last updated: 2026-05-12

About NORETHINDRONE ACETATE AND ETHINYL ESTRADIOL AND FERROUS FUMARATE

NORETHINDRONE ACETATE AND ETHINYL ESTRADIOL AND FERROUS FUMARATE is a medication tracked in the FDA Adverse Event Reporting System (FAERS), manufactured by Teva Pharmaceuticals USA, Inc.. Based on analysis of 4,509 FDA adverse event reports, NORETHINDRONE ACETATE AND ETHINYL ESTRADIOL AND FERROUS FUMARATE has a safety score of 65 out of 100. This moderate score indicates a notable volume of adverse event reports that patients and providers should be aware of. The most commonly reported adverse reactions for NORETHINDRONE ACETATE AND ETHINYL ESTRADIOL AND FERROUS FUMARATE include NAUSEA, HEADACHE, DRUG INEFFECTIVE, FATIGUE, PAIN. This page provides a comprehensive breakdown of reported side effects, safety signals, patient demographics, and AI-powered safety analysis for NORETHINDRONE ACETATE AND ETHINYL ESTRADIOL AND FERROUS FUMARATE.

AI Safety Analysis

Norethindrone Acetate And Ethinyl Estradiol And Ferrous Fumarate has a safety concern score of 65 out of 100, placing it in the elevated concern category based on analysis of FDA adverse event data. The FDA has received approximately 4,509 adverse event reports for this medication, which is primarily manufactured by Teva Pharmaceuticals Usa, Inc..

The most commonly reported adverse events include Nausea, Headache, Drug Ineffective. Of classified reports, 37.6% were designated as serious by the FDA, meaning they involved hospitalization, disability, or other significant medical outcomes. The most common adverse reactions include nausea, headache, and fatigue, with a significant number of reports involving serious conditions like pulmonary embolism and deep vein thrombosis.

A diverse range of reactions were reported, indicating potential for multiple side effects. The majority of reports were non-serious, but the serious condition reports were concerning, particularly for cardiovascular issues. The drug is primarily used in females, with the majority of reports coming from young adults.

Patients taking Norethindrone Acetate And Ethinyl Estradiol And Ferrous Fumarate should monitor for the commonly reported side effects and contact their healthcare provider if they experience any unusual symptoms. Drug interactions and warnings include the potential for serious cardiovascular events, and patients should be monitored for signs of pulmonary embolism and deep vein thrombosis. Injection site reactions and pain are also common and should be managed This analysis is based on voluntary FDA adverse event reports and should not replace professional medical advice.

Safety Score: 65/100

Norethindrone Acetate And Ethinyl Estradiol And Ferrous Fumarate received a safety concern score of 65/100 (elevated concern). This is based on a 37.6% serious event ratio across 2,456 classified reports. The score accounts for 4,509 total adverse event reports and 100 distinct reaction types. This elevated score indicates a notable proportion of serious adverse events and warrants careful monitoring.

Top Adverse Reactions

NAUSEA205 reports
HEADACHE173 reports
DRUG INEFFECTIVE150 reports
FATIGUE136 reports
PAIN109 reports
VOMITING106 reports
ANXIETY99 reports
DIARRHOEA98 reports
DIZZINESS92 reports
RASH87 reports
PRURITUS82 reports
OFF LABEL USE81 reports
DEPRESSION76 reports
PRODUCT DOSE OMISSION ISSUE76 reports
INJECTION SITE PAIN68 reports
CONDITION AGGRAVATED67 reports
ABDOMINAL PAIN66 reports
ARTHRALGIA65 reports
DYSPNOEA64 reports
MALAISE62 reports
FEELING ABNORMAL60 reports
INSOMNIA57 reports
MIGRAINE56 reports
COVID 1954 reports
ABDOMINAL PAIN UPPER53 reports
DERMATITIS ATOPIC53 reports
URTICARIA50 reports
PRODUCT USE IN UNAPPROVED INDICATION48 reports
VAGINAL HAEMORRHAGE48 reports
MUSCLE SPASMS46 reports
PYREXIA46 reports
WEIGHT DECREASED44 reports
MENSTRUATION IRREGULAR41 reports
NASOPHARYNGITIS41 reports
PULMONARY EMBOLISM40 reports
SOMNOLENCE39 reports
WEIGHT INCREASED39 reports
INJURY38 reports
SINUSITIS38 reports
COUGH37 reports
PAIN IN EXTREMITY37 reports
PRODUCT SUBSTITUTION ISSUE37 reports
ABDOMINAL DISTENSION36 reports
PARAESTHESIA36 reports
ABDOMINAL DISCOMFORT35 reports
ALOPECIA35 reports
METRORRHAGIA35 reports
INJECTION SITE ERYTHEMA34 reports
BACK PAIN33 reports
CHEST PAIN33 reports
MYALGIA33 reports
PRODUCT QUALITY ISSUE33 reports
CONSTIPATION32 reports
HYPERHIDROSIS32 reports
HYPERSENSITIVITY31 reports
HYPOAESTHESIA31 reports
SUICIDAL IDEATION31 reports
URINARY TRACT INFECTION31 reports
DRY SKIN30 reports
ASTHMA29 reports
PSORIASIS29 reports
STRESS29 reports
INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION28 reports
INFECTION27 reports
DEEP VEIN THROMBOSIS26 reports
FALL26 reports
FLUSHING26 reports
PNEUMONIA26 reports
THROMBOSIS26 reports
TREMOR26 reports
ASTHENIA25 reports
COELIAC DISEASE25 reports
INJECTION SITE BRUISING25 reports
MENORRHAGIA25 reports
PRODUCT DOSE OMISSION25 reports
ACNE24 reports
DECREASED APPETITE24 reports
HYPERTENSION24 reports
INJECTION SITE SWELLING24 reports
SEIZURE24 reports
SURGERY24 reports
DRUG DOSE OMISSION23 reports
DYSMENORRHOEA23 reports
EMOTIONAL DISTRESS23 reports
INJECTION SITE REACTION23 reports
BLOOD PRESSURE INCREASED22 reports
BRONCHITIS22 reports
CROHN^S DISEASE22 reports
DEHYDRATION22 reports
DISCOMFORT22 reports
DYSPEPSIA22 reports
ERYTHEMA22 reports
ILLNESS22 reports
INCORRECT DOSE ADMINISTERED22 reports
UPPER RESPIRATORY TRACT INFECTION22 reports
AMENORRHOEA21 reports
DISTURBANCE IN ATTENTION21 reports
ECZEMA21 reports
HEART RATE INCREASED21 reports
INJECTION SITE PRURITUS21 reports

Key Safety Signals

  • Pulmonary embolism and deep vein thrombosis were reported as serious conditions.
  • A significant number of reports involved drug dose omission issues.
  • There were multiple reports of injection site reactions and pain.

Patient Demographics

Adverse event reports by sex: Female: 2,302, Unknown: 8, Male: 7. The most frequently reported age groups are age 24 (66 reports), age 30 (64 reports), age 28 (57 reports). These demographics reflect reporting patterns and may not represent the full patient population.

Report Outcomes

Out of 2,456 classified reports for NORETHINDRONE ACETATE AND ETHINYL ESTRADIOL AND FERROUS FUMARATE:

  • Serious: 923 reports (37.6%) — includes hospitalization, disability, life-threatening events, or death
  • Non-Serious: 1,533 reports (62.4%)
Serious 37.6%Non-Serious 62.4%

The FDA classifies an adverse event as “serious” if it results in death, hospitalization, disability, congenital anomaly, or requires intervention to prevent permanent damage.

Demographics Breakdown

Reports by Sex

Female2,302 (99.4%)
Unknown8 (0.3%)
Male7 (0.3%)

Reports by Age

Age 2466 reports
Age 3064 reports
Age 2857 reports
Age 1956 reports
Age 2155 reports
Age 2054 reports
Age 2253 reports
Age 2753 reports
Age 2351 reports
Age 2951 reports
Age 1749 reports
Age 2649 reports
Age 2548 reports
Age 3446 reports
Age 3145 reports
Age 3644 reports
Age 3542 reports
Age 3842 reports
Age 3241 reports
Age 1840 reports

Demographics reflect voluntary FDA adverse event reporting patterns and may not represent the full patient population.

Drug Interactions & Warnings

Drug interactions and warnings include the potential for serious cardiovascular events, and patients should be monitored for signs of pulmonary embolism and deep vein thrombosis. Injection site reactions and pain are also common and should be managed

What You Should Know

If you are taking Norethindrone Acetate And Ethinyl Estradiol And Ferrous Fumarate, here are important things to know. The most commonly reported side effects include nausea, headache, drug ineffective, fatigue, pain. While many of these may be mild and temporary, you should contact your healthcare provider if any symptoms are severe or persistent. Monitor for signs of serious cardiovascular events such as pulmonary embolism and deep vein thrombosis. Report any injection site reactions or pain to your healthcare provider. If you experience a serious adverse reaction, seek emergency medical attention immediately or call 911. You can report side effects to the FDA's MedWatch program at 1-800-FDA-1088.

Regulatory Context

The FDA continues to monitor the safety of this drug, and healthcare providers should report any serious adverse events to the FDA's MedWatch program. Patients should be informed about the potential for serious side effects and should follow prescrib

Frequently Asked Questions

How many adverse event reports has the FDA received for Norethindrone Acetate And Ethinyl Estradiol And Ferrous Fumarate?

The FDA has received approximately 4,509 adverse event reports associated with Norethindrone Acetate And Ethinyl Estradiol And Ferrous Fumarate. These reports come from healthcare professionals, consumers, and manufacturers through the FDA Adverse Event Reporting System (FAERS). Note that the number of reports does not directly indicate the frequency of side effects, as adverse events are voluntarily reported and may be underrepresented.

What are the most commonly reported side effects of Norethindrone Acetate And Ethinyl Estradiol And Ferrous Fumarate?

The most frequently reported adverse events for Norethindrone Acetate And Ethinyl Estradiol And Ferrous Fumarate include Nausea, Headache, Drug Ineffective, Fatigue, Pain. By volume, the top reported reactions are: Nausea (205 reports), Headache (173 reports), Drug Ineffective (150 reports). These figures reflect FDA adverse event reports and may not represent the true incidence rate of these side effects in all patients taking Norethindrone Acetate And Ethinyl Estradiol And Ferrous Fumarate.

What percentage of Norethindrone Acetate And Ethinyl Estradiol And Ferrous Fumarate adverse event reports are serious?

Out of 2,456 classified reports, 923 (37.6%) were classified as serious and 1,533 as non-serious. The FDA classifies an event as "serious" if it results in death, hospitalization, disability, or other medically significant outcomes. A higher serious-event ratio warrants closer attention but does not necessarily mean the drug is unsafe.

Who reports adverse events for Norethindrone Acetate And Ethinyl Estradiol And Ferrous Fumarate (by sex)?

Adverse event reports for Norethindrone Acetate And Ethinyl Estradiol And Ferrous Fumarate break down by patient sex as follows: Female: 2,302, Unknown: 8, Male: 7. This distribution reflects reporting patterns rather than actual risk differences between groups. Reporting rates can be influenced by prescribing patterns, disease demographics, and reporting behavior.

What age groups report the most side effects for Norethindrone Acetate And Ethinyl Estradiol And Ferrous Fumarate?

The most frequently reported age groups for Norethindrone Acetate And Ethinyl Estradiol And Ferrous Fumarate adverse events are: age 24: 66 reports, age 30: 64 reports, age 28: 57 reports, age 19: 56 reports, age 21: 55 reports. Age-related reporting patterns can reflect both the demographics of the patient population and potential age-related susceptibility to certain side effects.

Who manufactures Norethindrone Acetate And Ethinyl Estradiol And Ferrous Fumarate?

The primary manufacturer associated with Norethindrone Acetate And Ethinyl Estradiol And Ferrous Fumarate adverse event reports is Teva Pharmaceuticals Usa, Inc.. Multiple manufacturers may produce generic versions of this drug. The manufacturer listed reflects the most frequently reported brand in FDA adverse event data.

What other side effects have been reported for Norethindrone Acetate And Ethinyl Estradiol And Ferrous Fumarate?

Beyond the most common reactions, other reported adverse events for Norethindrone Acetate And Ethinyl Estradiol And Ferrous Fumarate include: Vomiting, Anxiety, Diarrhoea, Dizziness, Rash. Less common side effects can still be clinically significant. Patients should report any unusual symptoms to their healthcare provider.

How do I report a side effect from Norethindrone Acetate And Ethinyl Estradiol And Ferrous Fumarate?

You can report adverse events from Norethindrone Acetate And Ethinyl Estradiol And Ferrous Fumarate to the FDA through their MedWatch program at www.fda.gov/medwatch, by calling 1-800-FDA-1088, or by completing Form FDA 3500. Healthcare professionals, consumers, and manufacturers can all submit reports. Reporting helps the FDA monitor drug safety after approval.

What is Norethindrone Acetate And Ethinyl Estradiol And Ferrous Fumarate's safety score and what does it mean?

Norethindrone Acetate And Ethinyl Estradiol And Ferrous Fumarate has a safety concern score of 65 out of 100 (elevated concern). This score is calculated from the ratio of serious to non-serious adverse events, the diversity of reported reactions, and the overall volume of reports relative to usage. The most common adverse reactions include nausea, headache, and fatigue, with a significant number of reports involving serious conditions like pulmonary embolism and deep vein thrombosis.

What are the key safety signals for Norethindrone Acetate And Ethinyl Estradiol And Ferrous Fumarate?

Key safety signals identified in Norethindrone Acetate And Ethinyl Estradiol And Ferrous Fumarate's adverse event data include: Pulmonary embolism and deep vein thrombosis were reported as serious conditions.. A significant number of reports involved drug dose omission issues.. There were multiple reports of injection site reactions and pain.. These signals are derived from patterns in FDA reports and should be discussed with a healthcare provider for personalized assessment.

Does Norethindrone Acetate And Ethinyl Estradiol And Ferrous Fumarate interact with other drugs?

Drug interactions and warnings include the potential for serious cardiovascular events, and patients should be monitored for signs of pulmonary embolism and deep vein thrombosis. Injection site reactions and pain are also common and should be managed Always inform your healthcare provider about all medications, supplements, and over-the-counter drugs you are taking before starting Norethindrone Acetate And Ethinyl Estradiol And Ferrous Fumarate.

What should patients know before taking Norethindrone Acetate And Ethinyl Estradiol And Ferrous Fumarate?

Monitor for signs of serious cardiovascular events such as pulmonary embolism and deep vein thrombosis. Report any injection site reactions or pain to your healthcare provider.

Are Norethindrone Acetate And Ethinyl Estradiol And Ferrous Fumarate side effects well-documented?

Norethindrone Acetate And Ethinyl Estradiol And Ferrous Fumarate has 4,509 adverse event reports on file with the FDA. A diverse range of reactions were reported, indicating potential for multiple side effects. The volume of reports for Norethindrone Acetate And Ethinyl Estradiol And Ferrous Fumarate reflects both the drug's usage level and the vigilance of the reporting community.

What is the FDA's position on Norethindrone Acetate And Ethinyl Estradiol And Ferrous Fumarate?

The FDA continues to monitor the safety of this drug, and healthcare providers should report any serious adverse events to the FDA's MedWatch program. Patients should be informed about the potential for serious side effects and should follow prescrib For the most current regulatory information, check the FDA's drug labeling database or consult your pharmacist.

Related Drugs

Drugs related to NORETHINDRONE ACETATE AND ETHINYL ESTRADIOL AND FERROUS FUMARATE based on therapeutic use, drug class, or shared indications:

NORETHINDRONE ACETATE AND ETHINYL ESTRADIOL AND FERROUS FUMARATENoneNoneNoneNone
Important Disclaimer: This content is generated by AI analysis of FDA adverse event reports and is provided for informational purposes only. It is not medical advice. Adverse event reports submitted to the FDA do not prove that a medication caused the reported side effect. Always consult your healthcare provider before starting, stopping, or changing any medication. If you experience a serious side effect, contact your doctor or call 911 immediately.