TRIAMCINOLONE ACETONIDE

65/100 · Elevated

Manufactured by Chattem, Inc.

Triamcinolone Acetonide Adverse Events: Moderate Safety Concerns

105,327 FDA adverse event reports analyzed

Last updated: 2026-05-12

About TRIAMCINOLONE ACETONIDE

TRIAMCINOLONE ACETONIDE is a medication tracked in the FDA Adverse Event Reporting System (FAERS), manufactured by Chattem, Inc.. Based on analysis of 105,327 FDA adverse event reports, TRIAMCINOLONE ACETONIDE has a safety score of 65 out of 100. This moderate score indicates a notable volume of adverse event reports that patients and providers should be aware of. The most commonly reported adverse reactions for TRIAMCINOLONE ACETONIDE include DRUG INEFFECTIVE, OFF LABEL USE, PRURITUS, RASH, PAIN. This page provides a comprehensive breakdown of reported side effects, safety signals, patient demographics, and AI-powered safety analysis for TRIAMCINOLONE ACETONIDE.

AI Safety Analysis

Triamcinolone Acetonide has a safety concern score of 65 out of 100, placing it in the elevated concern category based on analysis of FDA adverse event data. The FDA has received approximately 105,327 adverse event reports for this medication, which is primarily manufactured by Chattem, Inc..

The most commonly reported adverse events include Drug Ineffective, Off Label Use, Pruritus. Of classified reports, 46.7% were designated as serious by the FDA, meaning they involved hospitalization, disability, or other significant medical outcomes. Triamcinolone Acetonide reports include a high number of serious adverse events, particularly infections and gastrointestinal issues.

The drug is frequently reported to be ineffective or used off-label, indicating potential misuse or lack of efficacy. Skin-related reactions, such as rash and pruritus, are common, suggesting a significant dermatological safety profile.

Patients taking Triamcinolone Acetonide should monitor for the commonly reported side effects and contact their healthcare provider if they experience any unusual symptoms. Triamcinolone Acetonide can cause various side effects, including infections and gastrointestinal issues. It should be used with caution, especially in patients with a history of these conditions. This analysis is based on voluntary FDA adverse event reports and should not replace professional medical advice.

Safety Score: 65/100

Triamcinolone Acetonide received a safety concern score of 65/100 (elevated concern). This is based on a 46.7% serious event ratio across 28,292 classified reports. The score accounts for 105,327 total adverse event reports and 100 distinct reaction types. This elevated score indicates a notable proportion of serious adverse events and warrants careful monitoring.

Top Adverse Reactions

DRUG INEFFECTIVE4,954 reports
OFF LABEL USE2,641 reports
PRURITUS2,231 reports
RASH2,205 reports
PAIN2,009 reports
FATIGUE1,944 reports
NAUSEA1,895 reports
HEADACHE1,724 reports
CONDITION AGGRAVATED1,615 reports
PRODUCT USE IN UNAPPROVED INDICATION1,574 reports
DIARRHOEA1,572 reports
VOMITING1,563 reports
DIZZINESS1,458 reports
ARTHRALGIA1,365 reports
MALAISE1,314 reports
PYREXIA1,261 reports
DYSPNOEA1,241 reports
INFUSION RELATED REACTION1,221 reports
URTICARIA1,215 reports
SYNOVITIS1,210 reports
WEIGHT INCREASED1,206 reports
RHEUMATOID ARTHRITIS1,194 reports
HYPERTENSION1,183 reports
HYPOAESTHESIA1,176 reports
JOINT SWELLING1,142 reports
HYPERSENSITIVITY1,113 reports
SWELLING1,110 reports
SYSTEMIC LUPUS ERYTHEMATOSUS1,099 reports
WOUND1,075 reports
INSOMNIA1,061 reports
NASOPHARYNGITIS1,040 reports
ALOPECIA1,020 reports
GLOSSODYNIA1,019 reports
PERIPHERAL SWELLING1,019 reports
MOBILITY DECREASED1,012 reports
PSORIATIC ARTHROPATHY997 reports
HAND DEFORMITY996 reports
TYPE 2 DIABETES MELLITUS990 reports
DRUG INTOLERANCE982 reports
WHEEZING977 reports
PAIN IN EXTREMITY975 reports
INFECTION959 reports
FOLLICULITIS951 reports
ABDOMINAL DISCOMFORT949 reports
IMPAIRED HEALING948 reports
PRODUCT USE ISSUE936 reports
STOMATITIS930 reports
FIBROMYALGIA928 reports
PSORIASIS919 reports
DRUG HYPERSENSITIVITY916 reports
IRRITABLE BOWEL SYNDROME907 reports
PNEUMONIA902 reports
PEMPHIGUS901 reports
GENERAL PHYSICAL HEALTH DETERIORATION895 reports
SLEEP DISORDER893 reports
INTENTIONAL PRODUCT USE ISSUE883 reports
ASTHENIA878 reports
CONFUSIONAL STATE877 reports
ARTHROPATHY874 reports
HEPATIC ENZYME INCREASED869 reports
WEIGHT DECREASED862 reports
HELICOBACTER INFECTION850 reports
DUODENAL ULCER PERFORATION838 reports
JOINT RANGE OF MOTION DECREASED828 reports
INJURY822 reports
INFLAMMATION818 reports
DRY SKIN814 reports
PERICARDITIS805 reports
DRY MOUTH798 reports
ABDOMINAL PAIN UPPER793 reports
SINUSITIS792 reports
BLISTER789 reports
MACULAR DEGENERATION779 reports
DEPRESSION771 reports
OBESITY769 reports
ILL DEFINED DISORDER757 reports
C REACTIVE PROTEIN INCREASED756 reports
PARAESTHESIA731 reports
THERAPEUTIC PRODUCT EFFECT INCOMPLETE725 reports
ANTI CYCLIC CITRULLINATED PEPTIDE ANTIBODY POSITIVE718 reports
DYSPEPSIA718 reports
OSTEOARTHRITIS716 reports
RHEUMATIC FEVER708 reports
DECREASED APPETITE705 reports
MUSCLE SPASMS703 reports
MEMORY IMPAIRMENT701 reports
ERYTHEMA700 reports
TREATMENT FAILURE693 reports
ABDOMINAL PAIN684 reports
BLOOD CHOLESTEROL INCREASED683 reports
THERAPEUTIC PRODUCT EFFECT DECREASED680 reports
DERMATITIS ATOPIC679 reports
MUSCLE INJURY669 reports
ANXIETY668 reports
LIP DRY655 reports
LIVER INJURY654 reports
FACET JOINT SYNDROME650 reports
MUSCULOSKELETAL STIFFNESS646 reports
MATERNAL EXPOSURE DURING PREGNANCY645 reports
RHEUMATOID FACTOR POSITIVE642 reports

Key Safety Signals

  • High incidence of serious adverse events (46.7%) including infections and gastrointestinal issues.
  • Frequent reports of drug ineffectiveness and off-label use.
  • Common skin-related reactions like rash and pruritus.

Patient Demographics

Adverse event reports by sex: Female: 15,964, Male: 8,391, Unknown: 16. The most frequently reported age groups are age 44 (828 reports), age 40 (648 reports), age 43 (588 reports). These demographics reflect reporting patterns and may not represent the full patient population.

Report Outcomes

Out of 28,292 classified reports for TRIAMCINOLONE ACETONIDE:

  • Serious: 13,219 reports (46.7%) — includes hospitalization, disability, life-threatening events, or death
  • Non-Serious: 15,073 reports (53.3%)
Serious 46.7%Non-Serious 53.3%

The FDA classifies an adverse event as “serious” if it results in death, hospitalization, disability, congenital anomaly, or requires intervention to prevent permanent damage.

Demographics Breakdown

Reports by Sex

Female15,964 (65.5%)
Male8,391 (34.4%)
Unknown16 (0.1%)

Reports by Age

Age 44828 reports
Age 40648 reports
Age 43588 reports
Age 71417 reports
Age 65386 reports
Age 60359 reports
Age 53331 reports
Age 68330 reports
Age 62326 reports
Age 56314 reports
Age 67308 reports
Age 63307 reports
Age 75302 reports
Age 69301 reports
Age 64293 reports
Age 59287 reports
Age 66284 reports
Age 58279 reports
Age 76274 reports
Age 70273 reports

Demographics reflect voluntary FDA adverse event reporting patterns and may not represent the full patient population.

Drug Interactions & Warnings

Triamcinolone Acetonide can cause various side effects, including infections and gastrointestinal issues. It should be used with caution, especially in patients with a history of these conditions.

What You Should Know

If you are taking Triamcinolone Acetonide, here are important things to know. The most commonly reported side effects include drug ineffective, off label use, pruritus, rash, pain. While many of these may be mild and temporary, you should contact your healthcare provider if any symptoms are severe or persistent. Follow prescribed dosages and use only as directed by a healthcare provider to minimize the risk of adverse effects. Report any unusual symptoms or side effects to your healthcare provider immediately. If you experience a serious adverse reaction, seek emergency medical attention immediately or call 911. You can report side effects to the FDA's MedWatch program at 1-800-FDA-1088.

Regulatory Context

The FDA continues to monitor the safety of Triamcinolone Acetonide, and regulatory actions may be taken based on ongoing safety data.

Frequently Asked Questions

How many adverse event reports has the FDA received for Triamcinolone Acetonide?

The FDA has received approximately 105,327 adverse event reports associated with Triamcinolone Acetonide. These reports come from healthcare professionals, consumers, and manufacturers through the FDA Adverse Event Reporting System (FAERS). Note that the number of reports does not directly indicate the frequency of side effects, as adverse events are voluntarily reported and may be underrepresented.

What are the most commonly reported side effects of Triamcinolone Acetonide?

The most frequently reported adverse events for Triamcinolone Acetonide include Drug Ineffective, Off Label Use, Pruritus, Rash, Pain. By volume, the top reported reactions are: Drug Ineffective (4,954 reports), Off Label Use (2,641 reports), Pruritus (2,231 reports). These figures reflect FDA adverse event reports and may not represent the true incidence rate of these side effects in all patients taking Triamcinolone Acetonide.

What percentage of Triamcinolone Acetonide adverse event reports are serious?

Out of 28,292 classified reports, 13,219 (46.7%) were classified as serious and 15,073 as non-serious. The FDA classifies an event as "serious" if it results in death, hospitalization, disability, or other medically significant outcomes. A higher serious-event ratio warrants closer attention but does not necessarily mean the drug is unsafe.

Who reports adverse events for Triamcinolone Acetonide (by sex)?

Adverse event reports for Triamcinolone Acetonide break down by patient sex as follows: Female: 15,964, Male: 8,391, Unknown: 16. This distribution reflects reporting patterns rather than actual risk differences between groups. Reporting rates can be influenced by prescribing patterns, disease demographics, and reporting behavior.

What age groups report the most side effects for Triamcinolone Acetonide?

The most frequently reported age groups for Triamcinolone Acetonide adverse events are: age 44: 828 reports, age 40: 648 reports, age 43: 588 reports, age 71: 417 reports, age 65: 386 reports. Age-related reporting patterns can reflect both the demographics of the patient population and potential age-related susceptibility to certain side effects.

Who manufactures Triamcinolone Acetonide?

The primary manufacturer associated with Triamcinolone Acetonide adverse event reports is Chattem, Inc.. Multiple manufacturers may produce generic versions of this drug. The manufacturer listed reflects the most frequently reported brand in FDA adverse event data.

What other side effects have been reported for Triamcinolone Acetonide?

Beyond the most common reactions, other reported adverse events for Triamcinolone Acetonide include: Fatigue, Nausea, Headache, Condition Aggravated, Product Use In Unapproved Indication. Less common side effects can still be clinically significant. Patients should report any unusual symptoms to their healthcare provider.

How do I report a side effect from Triamcinolone Acetonide?

You can report adverse events from Triamcinolone Acetonide to the FDA through their MedWatch program at www.fda.gov/medwatch, by calling 1-800-FDA-1088, or by completing Form FDA 3500. Healthcare professionals, consumers, and manufacturers can all submit reports. Reporting helps the FDA monitor drug safety after approval.

What is Triamcinolone Acetonide's safety score and what does it mean?

Triamcinolone Acetonide has a safety concern score of 65 out of 100 (elevated concern). This score is calculated from the ratio of serious to non-serious adverse events, the diversity of reported reactions, and the overall volume of reports relative to usage. Triamcinolone Acetonide reports include a high number of serious adverse events, particularly infections and gastrointestinal issues.

What are the key safety signals for Triamcinolone Acetonide?

Key safety signals identified in Triamcinolone Acetonide's adverse event data include: High incidence of serious adverse events (46.7%) including infections and gastrointestinal issues.. Frequent reports of drug ineffectiveness and off-label use.. Common skin-related reactions like rash and pruritus.. These signals are derived from patterns in FDA reports and should be discussed with a healthcare provider for personalized assessment.

Does Triamcinolone Acetonide interact with other drugs?

Triamcinolone Acetonide can cause various side effects, including infections and gastrointestinal issues. It should be used with caution, especially in patients with a history of these conditions. Always inform your healthcare provider about all medications, supplements, and over-the-counter drugs you are taking before starting Triamcinolone Acetonide.

What should patients know before taking Triamcinolone Acetonide?

Follow prescribed dosages and use only as directed by a healthcare provider to minimize the risk of adverse effects. Report any unusual symptoms or side effects to your healthcare provider immediately.

Are Triamcinolone Acetonide side effects well-documented?

Triamcinolone Acetonide has 105,327 adverse event reports on file with the FDA. The drug is frequently reported to be ineffective or used off-label, indicating potential misuse or lack of efficacy. The volume of reports for Triamcinolone Acetonide reflects both the drug's usage level and the vigilance of the reporting community.

What is the FDA's position on Triamcinolone Acetonide?

The FDA continues to monitor the safety of Triamcinolone Acetonide, and regulatory actions may be taken based on ongoing safety data. For the most current regulatory information, check the FDA's drug labeling database or consult your pharmacist.

Related Drugs

Drugs related to TRIAMCINOLONE ACETONIDE based on therapeutic use, drug class, or shared indications:

AmoxicillinIbuprofenMetformin
Important Disclaimer: This content is generated by AI analysis of FDA adverse event reports and is provided for informational purposes only. It is not medical advice. Adverse event reports submitted to the FDA do not prove that a medication caused the reported side effect. Always consult your healthcare provider before starting, stopping, or changing any medication. If you experience a serious side effect, contact your doctor or call 911 immediately.