BIMATOPROST

45/100 · Moderate

Manufactured by Allergan, Inc.

Bimatoprost Adverse Events: Ocular and Mild Systemic Reactions Predominate

44,865 FDA adverse event reports analyzed

Last updated: 2026-05-12

About BIMATOPROST

BIMATOPROST is a medication tracked in the FDA Adverse Event Reporting System (FAERS), manufactured by Allergan, Inc.. Based on analysis of 44,865 FDA adverse event reports, BIMATOPROST has a safety score of 45 out of 100. This moderate score indicates a notable volume of adverse event reports that patients and providers should be aware of. The most commonly reported adverse reactions for BIMATOPROST include DRUG INEFFECTIVE, TREATMENT FAILURE, OCULAR HYPERAEMIA, EYE IRRITATION, MADAROSIS. This page provides a comprehensive breakdown of reported side effects, safety signals, patient demographics, and AI-powered safety analysis for BIMATOPROST.

AI Safety Analysis

Bimatoprost has a safety concern score of 45 out of 100, placing it in the moderate concern category based on analysis of FDA adverse event data. The FDA has received approximately 44,865 adverse event reports for this medication, which is primarily manufactured by Allergan, Inc..

The most commonly reported adverse events include Drug Ineffective, Treatment Failure, Ocular Hyperaemia. Of classified reports, 26.9% were designated as serious by the FDA, meaning they involved hospitalization, disability, or other significant medical outcomes. The majority of adverse events are ocular in nature, with ocular hyperaemia and eye irritation being the most common.

Serious adverse events account for 26.9% of total reports, indicating a moderate risk. The most frequent reactions include ocular hyperaemia, eye irritation, and madarosis, suggesting a notable impact on ocular health.

Patients taking Bimatoprost should monitor for the commonly reported side effects and contact their healthcare provider if they experience any unusual symptoms. Bimatoprost should be used with caution in patients with pre-existing ocular conditions, and its use may interact with other ocular medications. Patients should be advised to follow the prescribed dosing schedule and technique. This analysis is based on voluntary FDA adverse event reports and should not replace professional medical advice.

Safety Score: 45/100

Bimatoprost received a safety concern score of 45/100 (moderate concern). This is based on a 26.9% serious event ratio across 28,129 classified reports. The score accounts for 44,865 total adverse event reports and 100 distinct reaction types. This moderate score is typical for widely prescribed medications with established safety profiles.

Top Adverse Reactions

DRUG INEFFECTIVE4,071 reports
TREATMENT FAILURE3,077 reports
OCULAR HYPERAEMIA2,333 reports
EYE IRRITATION1,841 reports
MADAROSIS1,386 reports
EYE PRURITUS1,320 reports
ERYTHEMA OF EYELID1,012 reports
EYE PAIN937 reports
HYPERSENSITIVITY851 reports
VISION BLURRED834 reports
INTRAOCULAR PRESSURE INCREASED715 reports
FATIGUE705 reports
OFF LABEL USE701 reports
HEADACHE674 reports
DRY EYE647 reports
EYE SWELLING646 reports
WRONG TECHNIQUE IN PRODUCT USAGE PROCESS583 reports
DYSPNOEA543 reports
INAPPROPRIATE SCHEDULE OF DRUG ADMINISTRATION539 reports
EYELIDS PRURITUS530 reports
DIZZINESS517 reports
ERYTHEMA510 reports
NAUSEA506 reports
DIARRHOEA496 reports
INCORRECT DOSE ADMINISTERED494 reports
SKIN HYPERPIGMENTATION480 reports
FALL467 reports
VISUAL IMPAIRMENT459 reports
ASTHENIA444 reports
PRURITUS422 reports
EYELID OEDEMA419 reports
WRONG TECHNIQUE IN DRUG USAGE PROCESS404 reports
PAIN398 reports
DEATH378 reports
LACRIMATION INCREASED376 reports
EYELID IRRITATION373 reports
PRODUCT DOSE OMISSION ISSUE357 reports
RASH351 reports
CATARACT337 reports
INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION329 reports
GLAUCOMA324 reports
MALAISE320 reports
EYE DISCHARGE305 reports
THERAPEUTIC RESPONSE DECREASED300 reports
GROWTH OF EYELASHES295 reports
SKIN DISCOLOURATION291 reports
PNEUMONIA287 reports
VISUAL ACUITY REDUCED285 reports
TRICHORRHEXIS281 reports
BLEPHARAL PIGMENTATION279 reports
ARTHRALGIA277 reports
VOMITING273 reports
DRUG DOSE OMISSION272 reports
PAIN IN EXTREMITY266 reports
COUGH264 reports
DRUG HYPERSENSITIVITY264 reports
WEIGHT DECREASED259 reports
ACCIDENTAL EXPOSURE TO PRODUCT250 reports
INSOMNIA245 reports
PRODUCT QUALITY ISSUE239 reports
HYPERTENSION235 reports
EYE DISORDER223 reports
FOREIGN BODY SENSATION IN EYES213 reports
DECREASED APPETITE206 reports
BLOOD PRESSURE INCREASED201 reports
CONSTIPATION200 reports
OCULAR DISCOMFORT195 reports
PRODUCT PACKAGING QUANTITY ISSUE195 reports
BACK PAIN193 reports
GAIT DISTURBANCE189 reports
ANAEMIA188 reports
HAIR GROWTH ABNORMAL188 reports
ANXIETY187 reports
HYPOTENSION184 reports
CONDITION AGGRAVATED179 reports
PYREXIA175 reports
URINARY TRACT INFECTION175 reports
PHOTOPHOBIA173 reports
FEELING ABNORMAL170 reports
DEPRESSION159 reports
PERIPHERAL SWELLING159 reports
SWELLING OF EYELID158 reports
BLINDNESS157 reports
CONFUSIONAL STATE157 reports
MYALGIA155 reports
SOMNOLENCE154 reports
EXPIRED PRODUCT ADMINISTERED153 reports
ABDOMINAL DISCOMFORT152 reports
CHEST PAIN150 reports
ATRIAL FIBRILLATION149 reports
DRUG ADMINISTERED AT INAPPROPRIATE SITE148 reports
EYELID PAIN148 reports
NASOPHARYNGITIS148 reports
CEREBROVASCULAR ACCIDENT147 reports
OEDEMA PERIPHERAL147 reports
NO ADVERSE EVENT146 reports
ALOPECIA144 reports
BLOOD GLUCOSE INCREASED143 reports
WEIGHT INCREASED143 reports
BURNING SENSATION141 reports

Key Safety Signals

  • Ocular hyperaemia and eye irritation are the most reported reactions, indicating potential ocular irritation.
  • Serious adverse events such as vision blurring and increased intraocular pressure are reported, though less frequently.
  • Skin hyperpigmentation and eyelid oedema are also notable, suggesting potential systemic effects.

Patient Demographics

Adverse event reports by sex: Female: 19,553, Male: 6,868, Unknown: 42. The most frequently reported age groups are age 70 (346 reports), age 75 (337 reports), age 68 (335 reports). These demographics reflect reporting patterns and may not represent the full patient population.

Report Outcomes

Out of 28,129 classified reports for BIMATOPROST:

  • Serious: 7,576 reports (26.9%) — includes hospitalization, disability, life-threatening events, or death
  • Non-Serious: 20,553 reports (73.1%)
Serious 26.9%Non-Serious 73.1%

The FDA classifies an adverse event as “serious” if it results in death, hospitalization, disability, congenital anomaly, or requires intervention to prevent permanent damage.

Demographics Breakdown

Reports by Sex

Female19,553 (73.9%)
Male6,868 (26.0%)
Unknown42 (0.2%)

Reports by Age

Age 70346 reports
Age 75337 reports
Age 68335 reports
Age 72333 reports
Age 66331 reports
Age 74312 reports
Age 69311 reports
Age 79307 reports
Age 67295 reports
Age 78295 reports
Age 71292 reports
Age 76292 reports
Age 65287 reports
Age 73287 reports
Age 60284 reports
Age 62278 reports
Age 77271 reports
Age 63266 reports
Age 64257 reports
Age 80255 reports

Demographics reflect voluntary FDA adverse event reporting patterns and may not represent the full patient population.

Drug Interactions & Warnings

Bimatoprost should be used with caution in patients with pre-existing ocular conditions, and its use may interact with other ocular medications. Patients should be advised to follow the prescribed dosing schedule and technique.

What You Should Know

If you are taking Bimatoprost, here are important things to know. The most commonly reported side effects include drug ineffective, treatment failure, ocular hyperaemia, eye irritation, madarosis. While many of these may be mild and temporary, you should contact your healthcare provider if any symptoms are severe or persistent. Follow the prescribed dosing schedule and technique to minimize the risk of adverse events. Report any vision changes or ocular discomfort to your healthcare provider promptly. If you experience a serious adverse reaction, seek emergency medical attention immediately or call 911. You can report side effects to the FDA's MedWatch program at 1-800-FDA-1088.

Regulatory Context

The FDA continues to monitor Bimatoprost for safety, and updates will be provided as necessary. Healthcare providers should report any adverse events to the FDA's MedWatch program.

Frequently Asked Questions

How many adverse event reports has the FDA received for Bimatoprost?

The FDA has received approximately 44,865 adverse event reports associated with Bimatoprost. These reports come from healthcare professionals, consumers, and manufacturers through the FDA Adverse Event Reporting System (FAERS). Note that the number of reports does not directly indicate the frequency of side effects, as adverse events are voluntarily reported and may be underrepresented.

What are the most commonly reported side effects of Bimatoprost?

The most frequently reported adverse events for Bimatoprost include Drug Ineffective, Treatment Failure, Ocular Hyperaemia, Eye Irritation, Madarosis. By volume, the top reported reactions are: Drug Ineffective (4,071 reports), Treatment Failure (3,077 reports), Ocular Hyperaemia (2,333 reports). These figures reflect FDA adverse event reports and may not represent the true incidence rate of these side effects in all patients taking Bimatoprost.

What percentage of Bimatoprost adverse event reports are serious?

Out of 28,129 classified reports, 7,576 (26.9%) were classified as serious and 20,553 as non-serious. The FDA classifies an event as "serious" if it results in death, hospitalization, disability, or other medically significant outcomes. A higher serious-event ratio warrants closer attention but does not necessarily mean the drug is unsafe.

Who reports adverse events for Bimatoprost (by sex)?

Adverse event reports for Bimatoprost break down by patient sex as follows: Female: 19,553, Male: 6,868, Unknown: 42. This distribution reflects reporting patterns rather than actual risk differences between groups. Reporting rates can be influenced by prescribing patterns, disease demographics, and reporting behavior.

What age groups report the most side effects for Bimatoprost?

The most frequently reported age groups for Bimatoprost adverse events are: age 70: 346 reports, age 75: 337 reports, age 68: 335 reports, age 72: 333 reports, age 66: 331 reports. Age-related reporting patterns can reflect both the demographics of the patient population and potential age-related susceptibility to certain side effects.

Who manufactures Bimatoprost?

The primary manufacturer associated with Bimatoprost adverse event reports is Allergan, Inc.. Multiple manufacturers may produce generic versions of this drug. The manufacturer listed reflects the most frequently reported brand in FDA adverse event data.

What other side effects have been reported for Bimatoprost?

Beyond the most common reactions, other reported adverse events for Bimatoprost include: Eye Pruritus, Erythema Of Eyelid, Eye Pain, Hypersensitivity, Vision Blurred. Less common side effects can still be clinically significant. Patients should report any unusual symptoms to their healthcare provider.

How do I report a side effect from Bimatoprost?

You can report adverse events from Bimatoprost to the FDA through their MedWatch program at www.fda.gov/medwatch, by calling 1-800-FDA-1088, or by completing Form FDA 3500. Healthcare professionals, consumers, and manufacturers can all submit reports. Reporting helps the FDA monitor drug safety after approval.

What is Bimatoprost's safety score and what does it mean?

Bimatoprost has a safety concern score of 45 out of 100 (moderate concern). This score is calculated from the ratio of serious to non-serious adverse events, the diversity of reported reactions, and the overall volume of reports relative to usage. The majority of adverse events are ocular in nature, with ocular hyperaemia and eye irritation being the most common.

What are the key safety signals for Bimatoprost?

Key safety signals identified in Bimatoprost's adverse event data include: Ocular hyperaemia and eye irritation are the most reported reactions, indicating potential ocular irritation.. Serious adverse events such as vision blurring and increased intraocular pressure are reported, though less frequently.. Skin hyperpigmentation and eyelid oedema are also notable, suggesting potential systemic effects.. These signals are derived from patterns in FDA reports and should be discussed with a healthcare provider for personalized assessment.

Does Bimatoprost interact with other drugs?

Bimatoprost should be used with caution in patients with pre-existing ocular conditions, and its use may interact with other ocular medications. Patients should be advised to follow the prescribed dosing schedule and technique. Always inform your healthcare provider about all medications, supplements, and over-the-counter drugs you are taking before starting Bimatoprost.

What should patients know before taking Bimatoprost?

Follow the prescribed dosing schedule and technique to minimize the risk of adverse events. Report any vision changes or ocular discomfort to your healthcare provider promptly.

Are Bimatoprost side effects well-documented?

Bimatoprost has 44,865 adverse event reports on file with the FDA. Serious adverse events account for 26.9% of total reports, indicating a moderate risk. The volume of reports for Bimatoprost reflects both the drug's usage level and the vigilance of the reporting community.

What is the FDA's position on Bimatoprost?

The FDA continues to monitor Bimatoprost for safety, and updates will be provided as necessary. Healthcare providers should report any adverse events to the FDA's MedWatch program. For the most current regulatory information, check the FDA's drug labeling database or consult your pharmacist.

Related Drugs

Drugs related to BIMATOPROST based on therapeutic use, drug class, or shared indications:

TimololBetaxololMetipranololBrinzolamideBrimonidine
Important Disclaimer: This content is generated by AI analysis of FDA adverse event reports and is provided for informational purposes only. It is not medical advice. Adverse event reports submitted to the FDA do not prove that a medication caused the reported side effect. Always consult your healthcare provider before starting, stopping, or changing any medication. If you experience a serious side effect, contact your doctor or call 911 immediately.